Fibrosis News and Research

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Fibrosis is the growth of fibrous tissue.

Novel low molecular weight dextran-sulphate could play a key role in glaucoma treatment

Scientists at the University of Birmingham, UK, have shown that a novel low molecular weight dextran-sulphate, ILB® could play a key role in treating open angle glaucoma (OAG), a neurodegenerative disease that affects over 70 million people worldwide and causes irreversible blindness.

7 Jan 2021

ACE2 receptor is responsible for the wide host range of SARS-CoV-2

The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is thought to have a zoonotic origin, perhaps originating in a bat coronavirus with an unknown intermediate host. It is not only very infectious but has been found to infect a wide range of mammals, including dogs, cats, ferrets, hamsters, and minks, besides non-human primates. This range may be still higher, claims a recent preprint that appeared in January 2021 on the bioRxiv server.

6 Jan 2021

RedHill Biopharma: RHB-204 receives FDA Fast Track designation for treatment of NTM disease

RedHill Biopharma Ltd., a specialty biopharmaceutical company, today announced that RHB-204 has been granted Fast Track designation by the U.S. Food and Drug Administration for its development as a potential first-line, stand-alone, oral treatment of pulmonary nontuberculous mycobacteria (NTM) disease caused by Mycobacterium avium Complex (MAC) - a rare disease for which there is no FDA-approved first-line therapy.

6 Jan 2021

High altitude experts explain pneumolysis caused by COVID-19

The current COVID-19 pandemic has caused over 1 million deaths which can be attributed to its severe progressive pulmonary compromise.

21 Dec 2020

CN Bio and University of Melbourne announce partnership focused on respiratory therapies for recovering COVID-19 patients

CN Bio, a leading cell culture company, that has developed single and multi-organ microphysiological systems (MPS) to improve the accuracy and efficiency of drug discovery, today announced a collaboration with the University of Melbourne, focused on respiratory therapies for recovering COVID-19 patients.

18 Dec 2020

Research examines processes of lung scarring and chronic rejection of organ after transplantation

Two new papers examine the processes of lung scarring and chronic rejection of the organ after transplantation, and potential therapies to stop the graft, or transplanted organ and its tissue, from failing.

17 Dec 2020

Antifungal drug improves key biomarkers in the noses of patients with cystic fibrosis

A drug widely used to treat fungal infections improved key biomarkers in lung tissue cultures as well as in the noses of patients with cystic fibrosis, a clinical study by researchers at the University of Illinois Urbana-Champaign and the University of Iowa found.

17 Dec 2020

A protein may be responsible for triggering lung scarring in scleroderma patients

Systemic sclerosis is an autoimmune disease associated with inflammation and fibrosis, or scarring, that affects organs including the skin, heart, kidney and lungs.

17 Dec 2020

BU researchers awarded $2.4 million NIH grant to study idiopathic pulmonary fibrosis

Idiopathic pulmonary fibrosis (IPF) is a serious chronic disease that affects the tissue surrounding the air sacs in the lungs.

17 Dec 2020

Regulating a protein channel responsible for transporting chloride across cell membranes

Laboratory cell experiments and computer simulations have revealed molecular mechanisms regulating a protein channel responsible for transporting chloride and other charged molecules across cell membranes.

16 Dec 2020

CN Bio and the University of Melbourne collaborate to advance therapies for respiratory complications in recovered COVID-19 patients

From AXT Pty Ltd 16 Dec 2020

Novel MRI contrast agent shows strong potential as safer alternative to current products

Adding a contrast-enhancing agent to magnetic resonance imaging (MRI) significantly improves image quality and allows radiologists who interpret MRI scans to pick up subtle anatomic details and abnormalities that might otherwise be missed.

15 Dec 2020

New collaborative study to address key questions about COVID-19

A new nationwide study of more than 50,000 individuals is underway to determine factors that predict disease severity and long-term health impacts of COVID-19.

11 Dec 2020

Beta-blockers show anti-inflammatory effects in cirrhosis

Approximately 170,000 people die every year in Europe from the direct consequences of advanced chronic liver disease (cirrhosis).

10 Dec 2020

Study links insulin resistance and ozone exposure to interstitial lung disease

People with pre-diabetes or diabetes who live in ozone-polluted areas may have an increased risk for an irreversible disease with a high mortality rate.

9 Dec 2020

Researchers identify new way to disrupt process that promotes the growth of pancreatic cancers

Researchers say they've identified a way to disrupt a process that promotes the growth of pancreatic cancers -- one of the most difficult and deadly cancers to treat.

9 Dec 2020

Possible new antibiotic developed for drug-resistant pulmonary pathogen

Scientists from Johns Hopkins University and Medicine have developed a possible new antibiotic for a pathogen that is notoriously resistant to medications and frequently lethal for people with cystic fibrosis and other lung ailments.

8 Dec 2020

Research sheds light on the mystery cause of idiopathic pulmonary fibrosis

New research could shed light on the mystery cause of a lung disease that is a major killer, and potentially unlock new treatments.

8 Dec 2020

Lipid storm in severe COVID-19 linked to high COX/LOX pathway activity

A potentially valuable new study discusses the role of lipids in the hyper-inflammatory phenomena that take place within the lungs of patients with severe or critical COVID-19. Involving a large variety of specialized lipids with biological activity, this process includes the generation and release of pro and anti-inflammatory lipids.

8 Dec 2020

Researchers use novel technology to prevent destruction of specific proteins inside cells

Columbia researchers have created a new technology using synthetic llama antibodies to prevent specific proteins from being destroyed inside cells.

8 Dec 2020

Fibrosis News and Research

Further Reading

Novel low molecular weight dextran-sulphate could play a key role in glaucoma treatment

ACE2 receptor is responsible for the wide host range of SARS-CoV-2

RedHill Biopharma: RHB-204 receives FDA Fast Track designation for treatment of NTM disease

High altitude experts explain pneumolysis caused by COVID-19

CN Bio and University of Melbourne announce partnership focused on respiratory therapies for recovering COVID-19 patients

Research examines processes of lung scarring and chronic rejection of organ after transplantation

Antifungal drug improves key biomarkers in the noses of patients with cystic fibrosis

A protein may be responsible for triggering lung scarring in scleroderma patients

BU researchers awarded $2.4 million NIH grant to study idiopathic pulmonary fibrosis

Regulating a protein channel responsible for transporting chloride across cell membranes

CN Bio and the University of Melbourne collaborate to advance therapies for respiratory complications in recovered COVID-19 patients

Novel MRI contrast agent shows strong potential as safer alternative to current products

New collaborative study to address key questions about COVID-19

Beta-blockers show anti-inflammatory effects in cirrhosis

Study links insulin resistance and ozone exposure to interstitial lung disease

Researchers identify new way to disrupt process that promotes the growth of pancreatic cancers

Possible new antibiotic developed for drug-resistant pulmonary pathogen

Research sheds light on the mystery cause of idiopathic pulmonary fibrosis

Lipid storm in severe COVID-19 linked to high COX/LOX pathway activity

Researchers use novel technology to prevent destruction of specific proteins inside cells

Event guide: 4th Extra-Hepatic Lipid-Based Nanoparticles Delivery Summit eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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