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New CRISPR genome-editing technology helps scientists to explore many cancer-linked mutations

Genomic studies of cancer patients have revealed thousands of mutations linked to tumor development.

11 May 2023

Targeting uncontrolled inflammation may make tumors more responsive to treatment

Van Andel Institute scientists have pinpointed how a specific gene mutation triggers an inflammatory cascade that may drive development of treatment-resistant cancers.

11 May 2023

Scarring to the collagen framework causes dysfunction in Duchenne muscular dystrophy

Muscles that ache after a hard workout usually don't hurt for long, thanks to stem cells that rush to the injured site along "collagen highways" within the muscle and repair the damaged tissue.

11 May 2023

'Normal looking' skin may still carry sun-damaged DNA mutations that can trigger cancer

A University of Queensland study has found skin with few visible freckles or blemishes may still carry sun-damaged DNA mutations that can trigger cancer.

10 May 2023

Silenced p16 gene can drive colorectal cancer progression

Colorectal cancer is the fourth most common and second deadliest cancer. How colorectal cancer develops is not well understood, but a team led by researchers at Baylor College of Medicine reports in the Journal of Experimental & Clinical Cancer Research that silencing the gene p16, even though the DNA itself does not change, can drive colorectal cancer progression in animal models.

10 May 2023

Study explores the role of dynamin protein DYN-1 in regenerative axonal fusion

A study explores the role of the dynamin protein DYN-1 in axonal fusion. The axon is a long, thin protrusion of nerve cells that carries electrical impulses.

9 May 2023

Wistar scientists uncover a key mechanism as to how p53 suppresses tumors

The p53 gene is one of the most important in the human genome: the only role of the p53 protein that this gene encodes is to sense when a tumor is forming and to kill it.

5 May 2023

Advancing the development of vaccines through recombinant technology

In this interview, News-Medical talks to Dr. Amy Sheng, the head of CRO at Sino Biological, about current developments in the field of vaccine development through recombinant techniques.

From Sino Biological Inc. 4 May 2023

Organoid models provide new scientific insights into a rare childhood liver cancer

Scientists of the Princess Máxima Center for pediatric oncology and Hubrecht Institute in the Netherlands have revealed new scientific insights into the features of fibrolamellar carcinoma (FLC), a rare type of childhood liver cancer

3 May 2023

Finnish mitochondrial disease of newborns shows cancer-like changes in proliferating cells

A study found that a mitochondrial disease of newborns shows cancer-like changes in proliferating cells, causing tissues to age prematurely.

3 May 2023

Study examines the reinfection of SARS-CoV-2 variants in children

Researchers characterized the children with severe acute respiratory syndrome coronavirus 2 reinfection.

3 May 2023

Melanoma research unveils landscape of DNA and RNA alterations across multiple organs of metastasis

In a new translational study from UCLA Jonsson Comprehensive Cancer Center, researchers analyzed genetic changes in the organs of recently deceased patients to understand how metastatic cutaneous melanoma spreads in those who had initially benefited from precision therapies.

27 Apr 2023

Mutation News and Research

New CRISPR genome-editing technology helps scientists to explore many cancer-linked mutations

Targeting uncontrolled inflammation may make tumors more responsive to treatment

Scarring to the collagen framework causes dysfunction in Duchenne muscular dystrophy

'Normal looking' skin may still carry sun-damaged DNA mutations that can trigger cancer

Silenced p16 gene can drive colorectal cancer progression

Study explores the role of dynamin protein DYN-1 in regenerative axonal fusion

Wistar scientists uncover a key mechanism as to how p53 suppresses tumors

Advancing the development of vaccines through recombinant technology

Organoid models provide new scientific insights into a rare childhood liver cancer

Finnish mitochondrial disease of newborns shows cancer-like changes in proliferating cells

Study examines the reinfection of SARS-CoV-2 variants in children

Melanoma research unveils landscape of DNA and RNA alterations across multiple organs of metastasis

Do ketogenic diets elevate low-density lipoprotein cholesterol levels?

Researchers take key step toward developing a gene therapy for Usher syndrome type 1F

Colchicine therapy benefits pediatric long COVID patients suffering from recurring fever

New tool offers high accuracy in the interpretation of genetic mutations in disease genes

Using a gene signature to predict cancer patient's response to chemotherapy agent cisplatin

Newly discovered genetic variant increases risk of developing perianal Crohn's disease

Preclinical study reveals a potential new therapeutic approach to treating common lung cancer

Omicron spike N679K mutation acts as a loss-of-function mutation attenuating SARS-CoV-2 in vitro & in vivo

Improving healthcare sustainability through carbon data

A New Approach to Preventing Bladder Cancer Recurrence

Bringing real-time analytics to downstream bioprocess monitoring

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