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SARS-CoV-2 UK variant may induce more inflammation, study suggests

Since COVID-19 was first detected in December 2019 in Wuhan, China, many different variants of its causative virus – SARS-CoV-2 – have emerged. Through increased viral fitness, some of these have risen to predominance over earlier variants in a remarkably short period of time. New research, by a team of scientists at major institutions in France, examines the reasons behind this phenomenon in one such variant of concern (VOC), the so-called UK variant.

25 May 2021

Researchers take steps to standardize correlates of protection against SARS-CoV-2

Antibodies, Antibody, Assay, Coronavirus, Efficacy, Healthcare, Pandemic, Protein, Receptor, Research, Vaccine, Virus, Coronavirus Disease COVID-19,

24 May 2021

Researchers identify aluminum hydroxide/TLR9 agonist as potential adjuvant to improve RBD-based COVID-19 vaccine efficacy

The study findings reveal that RBD-based vaccines adjuvanted with the formulation can induce strong anti-SARS-CoV-2 neutralizing immunity in young and aged mice. The study is currently available on the bioRxiv* preprint server.

24 May 2021

Research suggests Garcinia kola extract might suppress severe COVID-19 cytokine storms

Researchers in the UK and Nigeria have conducted a study showing that Garcinia kola seed extract and garcinoic acid may provide therapeutic benefits in the late stage of severe coronavirus disease 2019 (COVID-19) and other coronavirus infections.

24 May 2021

Researchers define immune determinants of protection against SARS-CoV-2 in mice

Researchers in the United States have conducted a preclinical study defining the roles that different arms of the immune system play in fighting primary infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), as well as reinfection and infection following SARS-CoV-2 vaccination.

21 May 2021

Dupilumab considerably reduced asthma exacerbations in young children, shows VOYAGE trial

Results from the VOYAGE study of dupilumab (Dupixent) showed that the monoclonal antibody significantly reduced exacerbations in children ages 6-11 with uncontrolled moderate-to-severe asthma, compared to placebo, according to research presented at the ATS 2021 International Conference. VOYAGE (NCT02948959) is a recently completed randomized, placebo-controlled double-blind multicenter phase 3 clinical trial, that took place in a number of countries.

20 May 2021

Study identifies mechanism behind SARS-CoV-2 fusion of host cells

The spread of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is mediated by the fusion of the spike protein to nearby healthy cells. New research by German researchers sheds light on how this happens.

19 May 2021

Researchers use special "micro-grid" recording device to measure hippocampus activity

Researchers at UC San Francisco have observed a new feature of neural activity in the hippocampus - the brain's memory hub - that may explain how this vital brain region combines a diverse range of inputs into a multi-layered memories that can later be recalled.

17 May 2021

Enhanced version of CureVac’s COVID-19 vaccine could help address supply shortages

Researchers in Germany have demonstrated the preclinical effectiveness of a next-generation coronavirus disease 2019 (COVID-19) vaccine at enhancing antibody responses against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

16 May 2021

A magnetofluidic platform for SARS-CoV-2 variant and respiratory pathogen detection

Recent research published on the medRxiv* server has developed a portable, magnetofluidic cartridge platform, for automated PCR testing in <30 min, for rapid multiplexed screening of pathogens. A multidisciplinary team of researchers at Johns Hopkins University and the Johns Hopkins University School of Medicine developed these cartridges for multiplexed detection of SARS-CoV-2 with distinctive variant mutations or with Influenza A and B.

13 May 2021

Phosphatidic acid is a key common substrate for hepatitis C and SARS-CoV-2 replication

A new study, released as a preprint on the bioRxiv* server, focuses on the lipid molecule called phosphatidic acid (PA), showing its crucial role in the replication of this virus, and thus its potential as a target for therapeutic intervention.

13 May 2021

LLNL-developed thin-film electrodes generate never-before-seen recordings of brain activity

Thin-film electrodes developed at Lawrence Livermore National Laboratory have been used in human patients at the University of California, San Francisco, generating never-before-seen recordings of brain activity in the hippocampus, a region responsible for memory and other cognitive functions.

12 May 2021

Nanoscope presents optical gene delivery, OCT-guided electrophysiology platforms at ARVO annual meeting

Nanoscope Technologies LLC, a biotechnology company developing gene therapies for treatment of retinal diseases, is featuring multiple scientific presentations highlighting its groundbreaking research on optical gene delivery for vision restoration and OCT-guided electrophysiology platforms for characterization of retinal degeneration and assessment of efficacy of cell-gene therapy at the 2021 ARVO annual (virtual) meeting, May 1-7.

5 May 2021

The FDA expands collaboration with CN Bio to investigate lung-on-a-chip model for inhaled drug evaluation applications

CN Bio today announced the U.S. Food and Drug Administration (FDA) has extended their research collaboration, for a further three years.

From CN Bio 5 May 2021

Disposable face masks release potentially dangerous chemical pollutants

Swansea University scientists have uncovered potentially dangerous chemical pollutants that are released from disposable face masks when submerged in water.

5 May 2021

Rapid and sensitive SARS-CoV-2 detection from saliva using CRISPR

In a paper recently uploaded to the preprint server medRxiv by Edward Málaga Trillo et al. (April 29th, 2021), these methods are tested in combination with CRISPR-Cas detection in the field, demonstrating a sensitivity and specificity of 93.8% and 99%, respectively.

4 May 2021

Chemotherapy drugs delivered via nanoparticles could improve bowel cancer survival rates

Bowel cancer survival rates could be improved if chemotherapy drugs were delivered via tiny nanoparticles to the diseased organs rather than oral treatment.

3 May 2021

Monitoring O2 and CO2 Using Benchtop Bioreactors

Discover how to monitor O2 and CO2 Using Benchtop Bioreactors.

From Thermo Fisher Scientific – Pharmaceutical and Biopharmaceutical Solutions 30 Apr 2021

Using light-activated 3D printing to manufacture self-healing hydrogels with complex architectures

The scientific community is focusing its research into the multiple applications of Hydrogels, polymeric materials which contains a large amount of water, that have the potential to reproduce the features of biological tissues.

29 Apr 2021

New European research network addresses the effects of plastic particles on human health

Researching the effects of plastic particles on the human body and developing a health policy strategy for assessing the resulting risks is the goal of the new European research network PlasticsFatE. The University of Bayreuth, together with 26 other universities, institutes, and organizations from ten EU member states, is participating in the project.

29 Apr 2021

micro News and Research

SARS-CoV-2 UK variant may induce more inflammation, study suggests

Researchers take steps to standardize correlates of protection against SARS-CoV-2

Researchers identify aluminum hydroxide/TLR9 agonist as potential adjuvant to improve RBD-based COVID-19 vaccine efficacy

Research suggests Garcinia kola extract might suppress severe COVID-19 cytokine storms

Researchers define immune determinants of protection against SARS-CoV-2 in mice

Dupilumab considerably reduced asthma exacerbations in young children, shows VOYAGE trial

Study identifies mechanism behind SARS-CoV-2 fusion of host cells

Researchers use special "micro-grid" recording device to measure hippocampus activity

Enhanced version of CureVac’s COVID-19 vaccine could help address supply shortages

A magnetofluidic platform for SARS-CoV-2 variant and respiratory pathogen detection

Phosphatidic acid is a key common substrate for hepatitis C and SARS-CoV-2 replication

LLNL-developed thin-film electrodes generate never-before-seen recordings of brain activity

Nanoscope presents optical gene delivery, OCT-guided electrophysiology platforms at ARVO annual meeting

The FDA expands collaboration with CN Bio to investigate lung-on-a-chip model for inhaled drug evaluation applications

Disposable face masks release potentially dangerous chemical pollutants

Rapid and sensitive SARS-CoV-2 detection from saliva using CRISPR

Chemotherapy drugs delivered via nanoparticles could improve bowel cancer survival rates

Monitoring O2 and CO2 Using Benchtop Bioreactors

Using light-activated 3D printing to manufacture self-healing hydrogels with complex architectures

New European research network addresses the effects of plastic particles on human health

Event guide: 4th Extra-Hepatic Lipid-Based Nanoparticles Delivery Summit eBook

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

How Omics Technologies Are Transforming Biological Research and Drug Discovery

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