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Getting back to normal in Germany after coronavirus pandemic

The coronavirus disease (COVID-19) global pandemic is wreaking havoc across the globe, affecting 1.85 million people and has killed more than 114,000 people. The respiratory illness, akin to the SARS and MERS epidemics in the past, is infectious and dangerous to vulnerable populations, such as older adults and those with underlying health conditions.

13 Apr 2020

Promising COVID-19 drug treatments identified with new screening strategies

As scientists across the world race to find a pharmacological cure for coronavirus disease (COVID-19), an international research group has analyzed more than 10 thousand different compounds and identified six potential candidates, publishing their results in the leading scientific journal Nature.

12 Apr 2020

Unraveling interactions between metal ions and peptides may lead to new therapies for diseases

Copper ions could play a key role when peptide folding goes wrong and leads to harmful aggregates.

12 Apr 2020

New computer model can screen drugs for unintended cardiac side effects

UC Davis Health researchers have developed a computer model to screen drugs for unintended cardiac side effects, especially arrhythmia risk.

12 Apr 2020

PARP inhibitor drugs can be structurally modified to better kill tumor cells

A prospective "PARP inhibitor" drug that has struggled to show effectiveness in clinical trials against cancers can be structurally modified to greatly increase its power to kill tumor cells, researchers from Penn Medicine report this week in Science.

12 Apr 2020

Hair surface engineering using functional nano containers

"Hair surface engineering: modification of fibrous materials of biological origin using functional ceramic nano containers", a project headed by Rawil Fakhrullin, is supported by the Russian Science Foundation.

12 Apr 2020

Where cancers spread can give specific insights on disease traits

Kidney cancers that metastasize to the pancreas have a fundamentally different biology from those that metastasize elsewhere, with characteristics that can influence successful treatment, a study led by investigators with the UT Southwestern Kidney Cancer Program suggests.

12 Apr 2020

Many of Washington State’s illicit drug users want to reduce use

A new survey of people who inject illicit drugs in the state of Washington yields positive and important findings for policy makers as the world struggles to deal with the COVID-19 pandemic, said authors of the survey by the University of Washington and Public Health-Seattle & King County.

11 Apr 2020

Study: Bangladesh’s surface waters have high levels of antibiotic residues, chemicals

High levels of antibiotic residues, other medicines and chemicals present in Bangladesh's ponds, canals, lakes, rivers and other surface waters are contributing to a spike in antibiotic resistance in the country, says a new study.

11 Apr 2020

UofL researchers use computers in schools across Kentucky to identify drugs for COVID-19

The novel coronavirus may have K-12 students in Kentucky's school districts learning at home, but researchers at the University of Louisville are using the computing power of thousands of computers in classrooms across the state to identify drugs to treat COVID-19.

10 Apr 2020

Researchers design simple, cost-effective oxygen concentrators

The new virus is conquering the world. The more people who become infected with Sars-CoV-2, the more cases there will be in which severe illness will occur.

10 Apr 2020

Researchers identify COVID-19 drug lead treatments

An international team of researchers has tested more than 10,000 compounds to identify six drug candidates that may help treat COVID-19.

9 Apr 2020

Novel clinical trial fast tracks testing of COVID-19 therapies

A novel clinical trial developed by researchers at the University of Pittsburgh School of Medicine launched today at UPMC to address one of the most important debates during the COVID-19 pandemic:

9 Apr 2020

Researchers pinpoint genetic variation responsible for development of IBD

Researchers at Children's Hospital of Philadelphia have pinpointed a genetic variation responsible for driving the development of inflammatory bowel disease.

9 Apr 2020

Microneedle patches for potential COVID-19 vaccines or therapeutics

The COVID-19 pandemic is spreading over the world, causing panic and illness on a scale unprecedented in one hundred years. Even while the death toll nears 100,000, with over 1.5 million confirmed cases worldwide, public health experts and medical professionals are battling it using all the weapons available. Unfortunately, these are all too few.

9 Apr 2020

Hypertensive patients on ACE inhibitors and angiotensin receptor blockers may have improved COVID-19 prognosis

Emerging concerns that common antihypertensive treatment approaches with angiotensin-converting enzyme inhibitors (ACEIs) and angiotensin receptor blockers (ARBs) – jointly known as renin-angiotensin-aldosterone system (RAAS) inhibitors – may exert a negative effect in COVID-19 patients are not grounded in scientific evidence, as reported by researchers in a recent review article published in Mayo Clinic Proceedings journal.

9 Apr 2020

Swedish care for bipolar disorder shows inequalities

In Sweden, care for bipolar disorder shows inequalities. They are associated both with socioeconomic factors and with gender, according to research from the University of Gothenburg. For instance, lithium — the treatment deemed to have the most stabilizing effect on the disorder — is administered to men more often than to women.

9 Apr 2020

University of Utah Health, Intermountain Healthcare launch two clinical trials to treat COVID-19 patients

Researchers from Intermountain Healthcare and University of Utah Health in Salt Lake City have launched two vital clinical trials to test the effectiveness and safety of two drugs -hydroxychloroquine (HCQ) and azithromycin - to treat patients with COVID-19 (infection with the novel coronavirus).

9 Apr 2020

Clinical trial to investigate effectiveness of antimalarial drugs for COVID-19 treatment

Washington University School of Medicine in St. Louis is launching a clinical trial for patients hospitalized with COVID-19 at Barnes-Jewish Hospital.

9 Apr 2020

Researchers identify protein that plays critical role in cancer treatment-related heart damage

Many cancers can be successfully treated, but treatment itself often comes with risks as well. Cancer therapy that uses anthracyclines--a class of commonly used chemotherapy drugs--has been associated with heart damage that can eventually result in heart failure. It is thought to be the reason why heart disease is a leading cause of death in cancer survivors, immediately following cancer recurrence.

9 Apr 2020