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Researchers study the role of CHRNA3 and CHRNA5 genes in lung cancer

A recent study published in the October 2009 issue of the Journal of Thoracic Oncology determined that variations of specific genetic markers identified in previous research, or SNPs, may indicate a greater lung cancer risk in African Americans than in whites. The genes CHRNA3 and CHRNA5 may contribute to lung cancer risk due directly or through their association with nicotine dependence.

3 Oct 2009

Researchers screen decades-old frozen infant stool samples to detect norovirus

A search through decades-old frozen infant stool samples has yielded rich dividends for scientists from the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health.

3 Oct 2009

Grand Opportunity grant to pursue "whole-genome" sequencing of patients with autism

Children's Hospital Boston, with the Broad Institute and Harvard Medical School, has been awarded a Grand Opportunity grant from the National Institute of Mental Health as part of the federal stimulus package, to pursue "whole-genome" sequencing of patients with autism, using new technologies for rapid DNA sequencing to better understand autism's causes.

1 Oct 2009

Rush University receives grants to study how epigenomic changes define cognitive decline

The National Institutes of Health has awarded Rush University Medical Center approximately $5.5 million in grants to study how epigenetic changes - chemical modifications to genes that result from diet, aging, stress, or environmental exposures - define and contribute to memory formation and cognitive decline. Results from the studies could profoundly alter the way the medical community understands, diagnoses, and treats Alzheimer's disease, according to the researchers.

1 Oct 2009

OICR completes evaluation of NEB's new reagents for use with the Illumina Genome Analyzer

Dr. John McPherson, Platform Leader, Cancer Genomics and High-Throughput Screening, and Dr. Kamran Shazand, Project Manager, of the Ontario Institute for Cancer Research (OICR) led a team of scientists who have completed a thorough evaluation of the NEBNext(TM) DNA Sample Prep Reagents for use with OICR's Illumina® Genome Analyzer II.

From New England Biolabs 1 Oct 2009

Social environment plays vital role in breast cancer

Social environment can play an important role in the biology of disease, including breast cancer, and lead to significant differences in health outcome, according to results of a study published in Cancer Prevention Research, a journal of the American Association for Cancer Research.

1 Oct 2009

Biology and geography scientists explain the spread of HIV-1 epidemic in Africa

Scientists studying biology and geography may seem worlds apart, but together they have answered a question that has defied explanation about the spread of the HIV-1 epidemic in Africa.

1 Oct 2009

NCI and NHGRI collaborate to characterize genetic and genomic changes that occur in cancers

The University of North Carolina at Chapel Hill is one of twelve centers announced today by President Obama as part of an unprecedented large-scale, collaborative effort by the National Cancer Institute (NCI) and the National Human Genome Research Institute (NHGRI) to systematically characterize the genomic changes that occur in cancer.

1 Oct 2009

The Replikin Count of H1N1 virus’s infectivity gene shows continued elevation

The latest H1N1 genomic data shows a 50% drop in the Replikin CountTM of the virus’s replikins lethality gene since its recorded highs in April 2009. In contrast, the Replikin Count of the virus’s infectivity gene showed a continued elevation.

30 Sep 2009

Expression Analysis announces grants for research into complex diseases

Expression Analysis, Inc., the industry’s leading provider of genomic services for clinical trials and research, announced today a family of grants focused on one unifying purpose: To accelerate research into complex diseases and aid researchers in unlocking biological mysteries.

30 Sep 2009

IDRI and Academia Sinica sign Memorandum of Understanding

On behalf of The Lilly TB Drug Discovery Initiative, the Infectious Disease Research Institute (IDRI) today signed a Memorandum of Understanding (MOU) with Academia Sinica, a research institution based in Taiwan, to collaborate in target-based screening for the discovery of new tuberculosis (TB) drugs.

30 Sep 2009

NuGEN launches the Ovation WGA System for genome amplification

NuGEN Technologies Inc, a pace-setter in nucleic acid sample preparation, announces its entrance into the DNA market today with the Ovation WGA System, a linear, remarkably reliable, and more robust solution to whole genome amplification.

30 Sep 2009

Genetic factors play an important role in the development of type 1 diabetes

Under the direction of Prof. Dr. Anette Ziegler, scientists of the Diabetes Research Group at Helmholtz Zentrum München and Technische Universität München investigated the formation of antibodies to a zinc transporter in children with elevated risk for type 1 diabetes. The study provided indications of an early onset of the disease when specific antibodies in the blood and specific variants of the associated zinc transporter are present in the genome.

30 Sep 2009

Scientists use new techniques to explore vocal learning at molecular level

You can learn a lot from an animal. By manipulating the DNA of mice, flies, frogs and worms, scientists have discovered a great deal about the genes and molecules behind many of life's essential processes. These basic functions often work about the same in people as they do in "model" animals.

30 Sep 2009

SAIC-Frederick and Roche collaborate on technology advancements in sequencing cancer genes

National Cancer Institute contractor SAIC-Frederick, Inc., a wholly owned subsidiary of Science Applications International Corporation, and Roche Applied Science, a division of Roche Diagnostics Corporation, have signed a collaboration agreement to assess Roche’s advanced technologies to sequence the genomes of cancer research samples.

From Roche Sequencing and Life Science 29 Sep 2009

Scarab Genomics releases new E. Coli strain

ScarabXpress is the latest strain in the multiple-deletion series (MDS) of Scarab Genomics Clean Genome® E. coli. Based on the MDS™42 strain, ScarabXpress T7lac contains a chromosomal copy of the T7 RNA polymerase gene expressed from a unique, tightly controlled lac promoter.

29 Sep 2009

NHGRI and NIMH fund $45 million to establish Centers of Excellence in Genomic Science

The National Human Genome Research Institute (NHGRI) and National Institute of Mental Health (NIMH), both part of the National Institutes of Health, today announced grants expected to total approximately $45 million to establish new Centers of Excellence in Genomic Science at the Medical College of Wisconsin and University of North Carolina, Chapel Hill as well as to continue support of existing centers at Johns Hopkins University and the University of Southern California.

29 Sep 2009

NIH awards Johns Hopkins Epigenetic Center $16.8M to advance genomics research

Johns Hopkins' Center for the Epigenetics of Common Human Disease has been chosen as one of four recipients of a $45 million National Institutes of Health (NIH) grant for Centers of Excellence to advance genomics research. The Hopkins Center will receive $16.8 million over five years.

29 Sep 2009

NHGRI announces grant to establish Wisconsin Center of Excellence in Genomics Science

The National Human Genome Research Institute (NHGRI) of the National Institutes of Health today announced an $8 million, three-year grant to establish a Wisconsin Center of Excellence in Genomics Science.

29 Sep 2009

UNC awarded $8.6M for a new Center for Integrated Systems Genetics

Autism, depression, anxiety. Antipsychotic drug side effects. What are the genetic and environmental factors that underlie and contribute to these complex problems? And how do genes and environment interact to shape them?

28 Sep 2009

Genome News and Research

Researchers study the role of CHRNA3 and CHRNA5 genes in lung cancer

Researchers screen decades-old frozen infant stool samples to detect norovirus

Grand Opportunity grant to pursue "whole-genome" sequencing of patients with autism

Rush University receives grants to study how epigenomic changes define cognitive decline

OICR completes evaluation of NEB's new reagents for use with the Illumina Genome Analyzer

Social environment plays vital role in breast cancer

Biology and geography scientists explain the spread of HIV-1 epidemic in Africa

NCI and NHGRI collaborate to characterize genetic and genomic changes that occur in cancers

The Replikin Count of H1N1 virus’s infectivity gene shows continued elevation

Expression Analysis announces grants for research into complex diseases

IDRI and Academia Sinica sign Memorandum of Understanding

NuGEN launches the Ovation WGA System for genome amplification

Genetic factors play an important role in the development of type 1 diabetes

Scientists use new techniques to explore vocal learning at molecular level

SAIC-Frederick and Roche collaborate on technology advancements in sequencing cancer genes

Scarab Genomics releases new E. Coli strain

NHGRI and NIMH fund $45 million to establish Centers of Excellence in Genomic Science

NIH awards Johns Hopkins Epigenetic Center $16.8M to advance genomics research

NHGRI announces grant to establish Wisconsin Center of Excellence in Genomics Science

UNC awarded $8.6M for a new Center for Integrated Systems Genetics

The art of CRISPR: The power and promise of gene editing eBook

Lab Matters host Harriet Gould on building a more connected lab community

The Critical Role of Sample Storage in Drug Discovery and Development

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

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