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Metrion Biosciences and International Scientific Consortium publish data and new recommendations for in vitro risk assessment of the cardiac safety of new medicines

Metrion today announced it has contributed to two new peer-reviewed papers under the U.S. FDA CiPA (Comprehensive in vitro Proarrhythmia Assay) initiative.

From Metrion Biosciences Limited 7 Apr 2020

Researchers gain new insight into how lipids function within tears

New understandings of how lipids function within tears could lead to better drugs for treating dry eye disease.

7 Apr 2020

Research reveals a potential 'chink in the armor' of SARS-CoV-2

The scientists from Scripps Research, reveal a likely vulnerability or weakness of the coronavirus. An antibody, called CR3022, recovered from a survivor of the SARS outbreak in 2002, has shown a potential vulnerability of the novel coronavirus.

6 Apr 2020

Brown fat cells can translate energy into heat in an unexpected way

When we are exposed to sufficient cold or exercise, small clusters of brown fat cells in our bodies begin to burn up energy.

6 Apr 2020

Rush participates in clinical trial to test remdesivir as potential treatment for COVID-19

Rush University Medical Center is participating in a new clinical trial to test the effectiveness of the drug remdesivir in the treatment of coronavirus disease 2019 (COVID-19). This disease currently has no approved treatment.

6 Apr 2020

Texas A&M chemists focus on searching for drugs to treat COVID-19

In the wake of the novel coronavirus pandemic, Texas A&M University chemist Wenshe Ray Liu and his research team have focused their lab solely on searching for drugs to treat COVID-19.

6 Apr 2020

New antiviral drug could change the way doctors treat COVID-19

Scientists are hopeful that a new drug -- called EIDD-2801 -- could change the way doctors treat COVID-19. The drug shows promise in reducing lung damage, has finished testing in mice and will soon move to human clinical trials.

6 Apr 2020

Scientist proposes geroprotective strategies to reduce lethality of COVID-19 in the elderly

The Biogerontology Research Foundation, a registered UK charity supporting and promoting aging and longevity research worldwide since 2008, today announced the publication of a paper titled "Geroprotective and senoremediative strategies to reduce the comorbidity, infection rates, severity, and lethality in gerophilic and gerolavic infections" in the leading journal Aging.

6 Apr 2020

Experimental drug APN01 prevents COVID-19 infection in the lab

With the world gripped with the COVID-19 pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), there is a frantic rush to find an effective drug that can be used to treat the disease.

6 Apr 2020

DsbA-L gene may play a role in protecting respiratory function of the elderly

The lungs are constantly exposed to the external environment and maintain homeostasis by adapting to stress and tissue damage.

6 Apr 2020

Researchers uncover genetic mutation responsible for aggressive head and neck, lung cancers

Researchers from the Cancer Science Institute of Singapore at the National University of Singapore have uncovered a genetic variant in a gene called MET that is responsible for more aggressive growth of head and neck, and lung cancers.

6 Apr 2020

Nanopore reveals shape-shifting enzyme linked to catalysis

Scientists observed characteristics of an enzyme inside a nanopore, revealing that it can exist in four different folded states.

6 Apr 2020

‘You pray that you got the drug.’ Ailing couple gambles on trial for COVID-19 cure

For 10 days last month, they lay in side-by-side isolation units in a Seattle-area hospital, tethered to oxygen and struggling to breathe as the coronavirus ravaged their lungs.

6 Apr 2020

Mysterious heart damage, not just lung troubles, befalling COVID-19 patients

While the focus of the COVID-19 pandemic has been on respiratory problems and securing enough ventilators, doctors on the front lines are grappling with a new medical mystery.

6 Apr 2020

Using marine natural product to inhibit cervical cancer

A sponge found in Manado Bay, Indonesia, makes a molecule called manzamine A, which stops the growth of cervical cancer cells, according to a recent publication in the Journal of Natural Products submitted by researchers at the Medical University of South Carolina and their collaborators.

6 Apr 2020

Asthma and coronavirus disease - COVID-19

On the 11th of March 2020, the World Health Organization (WHO) declared COVID-19, caused by severe acute respiratory syndrome SARS CoV-2, a pandemic.

5 Apr 2020

COVID-19 and renin-angiotensin system inhibitors

A new viewpoint article published in the journal JAMA Network in April 2020 deals with the use of a widely used category of cardiovascular medications in COVID-19 patients with hypertension, diabetes, and cardiovascular disease (CVD). These are the most common medical conditions that are found in COVID-19 patients and contribute disproportionately to mortality.

5 Apr 2020

Antibody recovered from SARS survivor reveals potential vulnerability of new coronavirus

An antibody recovered from a survivor of the SARS epidemic in the early 2000s has revealed a potential vulnerability of the new coronavirus at the root of COVID-19, according to a study from scientists at Scripps Research.

3 Apr 2020

IRB Barcelona and Amazon join forces to develop computational tool in the fight against COVID-19

There are currently more than 10,000 scientific articles related to coronavirus infections. In fact, in recent weeks, research to combat COVID-19 has accelerated, and more than 4,000 new academic papers have been published on potential vaccines, therapies, and treatments.

3 Apr 2020

First genome sequences of SARS-CoV-2 viruses in Austria openly available

The first 21 SARS-CoV-2 genomes in Austria have now been completed and published within the scope of the “Mutational Dynamics of SARS-CoV-2” project recently launched by CeMM, the Research Center for Molecular Medicine of the Austrian Academy of Sciences, in close collaboration with the Medical University of Vienna.

3 Apr 2020