Antibody News and Research

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An antibody is a blood protein that is produced in response to and counteracts an antigen. Antibodies are produced in response to disease and help the body fight against the particular disease. In this way, antibodies help the body develop an immunity to disease.

New laboratory method for quickly detecting active anthrax proteins

A new laboratory method for quickly detecting active anthrax proteins within an infected blood sample at extremely low levels has been developed by researchers at the National Institute of Standards and Technology (NIST), the U.S. Army Medical Research Institute of Infectious Diseases and the National Cancer Institute.

29 Aug 2005

Carbohydrate-based vaccine against cancer?

Couldn't we be immunized against cancer? This sounds like a dream, but is in fact a thoroughly realistic research goal. American researchers have now taken an important step forward in the development of a cancer vaccine.

29 Aug 2005

New strategy to turn off the function of a special group of T cells to suppress immune response to tumors

A special stretch of genetic material may turn off the immune suppression that stymies attempts to fight cancer with a vaccine, said researchers at Baylor College of Medicine (BCM) at Houston.

26 Aug 2005

First clinical trial of a biologic nanoparticle designed to give back to cancer patients the tumor-busting gene they have lost

The phase I clinical study will enroll 20 patients with advanced solid cancers (including most common tumor types), and is the culmination of more than a decade of work by a team of researchers led by Professor Esther H. Chang, Ph.D. at the Lombardi Comprehensive Cancer Center.

25 Aug 2005

Susceptibility to Hepatitis A in patients with chronic liver disease due to Hepatitis C virus infection: missed opportunities for vaccination

A new study examining whether patients with chronic Hepatitis C virus (HCV) were routinely vaccinated against Hepatitis A virus (HAV) found that vaccination rates were low, even though HAV vaccination is recommended for patients with chronic liver disease.

23 Aug 2005

Study examines the incidence and risk factors associated with Hepatitis C infection in rural Egypt

The prevalence of antibodies to Hepatitis C Virus (HCV) in Egypt is among the highest in the world. From the 1950s until 1982 hundreds of thousands were infected during mass campaigns to control schistosomiasis (a parasitic disease) using mass therapy with intravenous antimony compounds, but little is known about current risk factors and rates of transmission.

23 Aug 2005

Gene therapy advance shows potential for developing improved treatment for hemophilia

A virus that typically infects insects could help with the development of gene therapy treatment for Hemophilia A, a condition in which even a bump on the knee can cause serious internal bleeding in people.

22 Aug 2005

Experimental vaccine can prime the immune system to help fight an aggressive form of lymphoma

Researchers at The University of Texas M. D. Anderson Cancer Center and the National Cancer Institute have found that an experimental vaccine can prime the immune system to help fight an aggressive form of lymphoma, even though prior therapy had eliminated virtually all of the B cells thought necessary to mount such a defense.

22 Aug 2005

Mutations in the targets of designer drugs critically influence their effectiveness

Two designer cancer drugs differed dramatically in a laboratory test comparing their ability to shut down a mutant, overactive growth signal in lung cancer cells, reports a team headed by scientists at the Dana-Farber Cancer Institute.

18 Aug 2005

Reasons for complications with kidney failure patients

Mayo Clinic researchers searching for explanations of high mortality rates among kidney failure patients undergoing hemodialysis are focusing their attention on the use of heparin, a drug used to reduce clotting of the blood.

18 Aug 2005

New hope for those deaf from immune system attack

A new study may one day help those deafened by immune system attack, and possibly also lead to a test that could show which patients may be helped by immediate steroid treatment.

16 Aug 2005

Pfizer acquires antibody discovery company Bioren

Pfizer and Bioren today announced the completion of a transaction in which Pfizer purchased all outstanding stock of Bioren for an undisclosed amount.

15 Aug 2005

Infusion nurses examine need for standards of practice in immunoglobulin therapy

A review article published in the July/August 2005 Journal of Infusion Nursing examines the need for established treatment guidelines to support doctors and nurses in correctly dosing and administering intravenous immunoglobulin (IVIG) as replacement therapy in patients with primary immunodeficiency (PI) disorders, who do not produce adequate levels of antibodies essential in fighting infectious diseases.

13 Aug 2005

Plasma exchange treatment shown most helpful for severe attacks in subtype of MS patients

A Mayo Clinic study demonstrates that only those multiple sclerosis (MS) patients with evidence for antibody deposition or complement activation -- immune cells that can cause tissue destruction -- in their lesions are likely to respond to plasma exchange, a treatment for acute MS attacks.

11 Aug 2005

Nasal vaccination with a proteosome-based adjuvant and glatiramer acetate clears beta-amyloid in a mouse model of Alzheimer's disease

Alzheimer disease (AD) is the most common form of senile dementia, with no effective treatment available. In a study appearing online on August 11 in advance of print publication of the September 1 issue of the Journal of Clinical Investigation, Howard Weiner and colleagues from Harvard describe a novel immunologic approach for the treatment of AD.

11 Aug 2005

Ground-breaking discoveries that provide hope of an alternative treatment option for haemophilia sufferers

Haemophilia is a hereditary blood disease, primarily affecting males, where the blood fails to clot causing potentially life-threatening 'bleeds'. About one in 6000 Australian males is born with haemophilia in severe, moderate or mild form. People with haemophilia rely on intravenous infusion of recombinant Factor VIII clotting protein.

11 Aug 2005

Researchers develop new diagnostic methods to better detect future monkeypox or smallpox outbreaks

The research also sheds new light on the 2003 monkeypox outbreak in the Midwest - monkeypox is closely related to smallpox. This new information suggests that the 2003 outbreak was larger than the 72 cases reported by the Centers for Disease Control and Prevention (CDC).

9 Aug 2005

U.S. company wants to commercialise breast milk

It has long been acknowledged that breast milk, with its minerals, digestive enzymes and antibodies, keeps babies healthy and boosts their intelligence.

7 Aug 2005

More than fifty percent of the U.S. population tested positive to one or more allergens

The new findings, based on data from the third National Health and Nutrition Examination Survey (NHANES III), shows that 54.3% of individuals aged 6-59 years old had a positive skin test response to at least one of the 10 allergens tested.

4 Aug 2005

Discovery may lead to new diagnostic tests for immunoglobulin A (IgA) deficiency and common variable immunodeficiency (CVID)

Defects in a single gene can result in two immune system disorders that leave affected individuals vulnerable to frequent or unusually severe infections, according to new findings reported in the August issue of Nature Genetics.

4 Aug 2005

Antibody News and Research

Further Reading

New laboratory method for quickly detecting active anthrax proteins

Carbohydrate-based vaccine against cancer?

New strategy to turn off the function of a special group of T cells to suppress immune response to tumors

First clinical trial of a biologic nanoparticle designed to give back to cancer patients the tumor-busting gene they have lost

Susceptibility to Hepatitis A in patients with chronic liver disease due to Hepatitis C virus infection: missed opportunities for vaccination

Study examines the incidence and risk factors associated with Hepatitis C infection in rural Egypt

Gene therapy advance shows potential for developing improved treatment for hemophilia

Experimental vaccine can prime the immune system to help fight an aggressive form of lymphoma

Mutations in the targets of designer drugs critically influence their effectiveness

Reasons for complications with kidney failure patients

New hope for those deaf from immune system attack

Pfizer acquires antibody discovery company Bioren

Infusion nurses examine need for standards of practice in immunoglobulin therapy

Plasma exchange treatment shown most helpful for severe attacks in subtype of MS patients

Nasal vaccination with a proteosome-based adjuvant and glatiramer acetate clears beta-amyloid in a mouse model of Alzheimer's disease

Ground-breaking discoveries that provide hope of an alternative treatment option for haemophilia sufferers

Researchers develop new diagnostic methods to better detect future monkeypox or smallpox outbreaks

U.S. company wants to commercialise breast milk

More than fifty percent of the U.S. population tested positive to one or more allergens

Discovery may lead to new diagnostic tests for immunoglobulin A (IgA) deficiency and common variable immunodeficiency (CVID)

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