Antibody News and Research

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An antibody is a blood protein that is produced in response to and counteracts an antigen. Antibodies are produced in response to disease and help the body fight against the particular disease. In this way, antibodies help the body develop an immunity to disease.

Compounds secreted by frog skin are potent blockers of HIV infection

The findings could lead to topical treatments for preventing HIV transmission, and they reinforce the value of preserving the Earth's biodiversity.

3 Oct 2005

Discovery of mechanism in the body that could lead to autoimmune diseases

Researchers at National Jewish Medical and Research Center have discovered a mechanism in the body that could lead to autoimmune diseases, such as lupus, rheumatoid arthritis, or diabetes.

3 Oct 2005

First identification of the genetic basis of disease in a patient with a complex I assembly defect

Mitochondrial complex I deficiency is one of the most common defects in patients with mitochondrial disease. The deficiency results from a failure to assemble the enzyme properly, but the nature of the molecular chaperones that are necessary for this process in mammals have remained obscure.

3 Oct 2005

Possible new therapy for lymphoma and leukemia patients

Marty Holmes, a landscaper from Stockton, Calif., had never heard of a regulatory T cell before his doctor suggested that it could be the key to helping him survive his cancer.

28 Sep 2005

Dengue and other viruses may have developed tricks that let them reproduce inside macrophages

A monoclonal antibody that can effectively treat mice infected with West Nile virus has an intriguing secret: Contrary to scientists' expectations, it does not block the virus's ability to attach to host cells. Instead, the antibody somehow stops the infectious process at a later point.

28 Sep 2005

Pursuit of potential drugs and small molecules that target the IGF-1 receptor

Pharmaceutical companies around the world still come knocking on Renato Baserga, M.D.,'s door. And for good reason.

27 Sep 2005

Researchers at Johns Hopkins have identified three new genetic mutations in brain tumors

...a discovery that could pave the way for more effective cancer treatments.

27 Sep 2005

Antibody in humans that quickly fights the smallpox virus

Researchers at the La Jolla Institute for Allergy & Immunology (LIAI) have made a major advancement toward protecting society against a smallpox outbreak by identifying an antibody in humans that quickly fights the smallpox virus.

26 Sep 2005

Mutations in receptor tyrosine kinases provide potential for highly-targeted cancer therapies

Scientists from J. Craig Venter Institute, Ludwig Institute for Cancer Research, and The Johns Hopkins University School of Medicine identified three novel mutations in two receptor tyrosine kinases in glioblastoma tumors using high throughput sequencing.

26 Sep 2005

Vaccine candidate? Researchers synthesize oligosaccharide from anthrax pathogen

For weeks a white powder caused fear and shock for the American population: a few days after the attacks on September 11th, 2001, four innocent people became the victims of letters that contained the powder - spores of the anthrax pathogen. German researchers have now synthesized a molecule characteristic of anthrax in the laboratory which may be the basis for a new anthrax vaccine.

26 Sep 2005

Aquaporin-4 is the first specific molecule to be defined as a target for the autoimmune response in any form of MS

Researchers have identified a molecular suspect in a disorder similar to multiple sclerosis (MS) that attacks the optic nerve and spinal cord, according to a report presented at the 130th annual meeting of the American Neurological Association in San Diego. The protein, called aquaporin-4, is a channel protein that allows water to move in and out of cells.

26 Sep 2005

Mutations in the gene, called PIG-A may help identify individuals at high risk for cancer

A new study to detect an elevated rate of mutations in a gene on the X chromosome holds promise for developing a test that could identify individuals at risk for developing cancer.

26 Sep 2005

Polymorphisms in a receptor called CD32 influence the response to antibody therapy in cancer

In a paper appearing online in advance of print publication of the October 1 issue of the Journal of Clinical Investigation, Adam Boruchov and colleagues from Memorial Sloan Kettering Cancer Center dissect the contributions of CD32 isoforms in human dendritic cell (DC) activation and function.

26 Sep 2005

Dilute bleach neutralizes the mold allergens that cause most mold-related health complaints

Researchers at National Jewish Medical and Research Center have demonstrated that dilute bleach not only kills common household mold, but may also neutralize the mold allergens that cause most mold-related health complaints.

22 Sep 2005

22 biomarkers that provide a more accurate screening for prostate

Researchers at the University of Michigan Comprehensive Cancer Center have identified a panel of 22 biomarkers that together provide a more accurate screening for prostate cancer than the current prostate specific antigen, or PSA, test.

22 Sep 2005

Simple organism can produce 10 trillion varieties of a single protein

A team led by University of California, San Diego biochemists has discovered the mechanism by which a simple organism can produce 10 trillion varieties of a single protein, a finding that provides a new tool to develop novel drugs.

21 Sep 2005

Vaccine against group B streptococcus

Common bacteria that live harmlessly in the gastrointestinal tract and vagina of 25 percent of women can become lethal if a newborn gets exposed to them during birth.

20 Sep 2005

Researchers identify three rapid diagnostic methods that can target antibodies commonly found in multiple sclerosis

Yale School of Medicine researchers have identified three rapid diagnostic methods that can target antibodies commonly found in multiple sclerosis (MS) patients, greatly improving potential diagnosis and treatment.

20 Sep 2005

O-GlcNAc sugar is a critical regulator of cells' natural life cycle

The discovery reveals that, when disturbed, this process could contribute to cancer or other diseases by failing to properly control the steps and timing of cell division, the researchers say. The findings are described in the Sept. 23 issue of the Journal of Biological Chemistry, available online now.

20 Sep 2005

SARS can infiltrate brain tissue

Severe acute respiratory syndrome (SARS), by its very name, indicates a disease of the respiratory tract. But SARS can also infiltrate brain tissue, causing significant central nervous system problems, according to an article in the Oct. 15 issue of Clinical Infectious Diseases, now available online.

20 Sep 2005

Antibody News and Research

Further Reading

Compounds secreted by frog skin are potent blockers of HIV infection

Discovery of mechanism in the body that could lead to autoimmune diseases

First identification of the genetic basis of disease in a patient with a complex I assembly defect

Possible new therapy for lymphoma and leukemia patients

Dengue and other viruses may have developed tricks that let them reproduce inside macrophages

Pursuit of potential drugs and small molecules that target the IGF-1 receptor

Researchers at Johns Hopkins have identified three new genetic mutations in brain tumors

Antibody in humans that quickly fights the smallpox virus

Mutations in receptor tyrosine kinases provide potential for highly-targeted cancer therapies

Vaccine candidate? Researchers synthesize oligosaccharide from anthrax pathogen

Aquaporin-4 is the first specific molecule to be defined as a target for the autoimmune response in any form of MS

Mutations in the gene, called PIG-A may help identify individuals at high risk for cancer

Polymorphisms in a receptor called CD32 influence the response to antibody therapy in cancer

Dilute bleach neutralizes the mold allergens that cause most mold-related health complaints

22 biomarkers that provide a more accurate screening for prostate

Simple organism can produce 10 trillion varieties of a single protein

Vaccine against group B streptococcus

Researchers identify three rapid diagnostic methods that can target antibodies commonly found in multiple sclerosis

O-GlcNAc sugar is a critical regulator of cells' natural life cycle

SARS can infiltrate brain tissue

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