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New MRI approach can be important tool for diagnosing, tracking MS progression

New imaging research from Western University (London, Canada) has demonstrated that a magnetic resonance imaging approach called quantitative susceptibility mapping can be an important tool for diagnosing and tracking the progression of Multiple Sclerosis and other neurological diseases.

20 Dec 2013

New research assesses nanomedicine-based approaches for treating cancer

As cancer maintains its standing as the second leading cause of death in the U.S., researchers have continued their quest for safer and more effective treatments. Among the most promising advances has been the rise of nanomedicine, the application of tiny materials and devices whose sizes are measured in the billionths of a meter to detect, diagnose and treat disease.

20 Dec 2013

Researchers receive 3 Patient-Centered Outcomes Research Institute awards from PCORI

Research teams at Group Health Research Institute have been approved for funding awards by the Patient-Centered Outcomes Research Institute (PCORI) to study opioid therapy and asthma-and to help expand a health data network that will be part of PCORnet: the National Patient-Centered National Clinical Research Network.

20 Dec 2013

Australian Therapeutic Goods Administration approves Genzyme's Lemtrada for multiple sclerosis

Genzyme, a Sanofi company, announced today that the Australian Therapeutic Goods Administration has approved Lemtrada (alemtuzumab) for the treatment of relapsing forms of multiple sclerosis for patients with active disease defined by clinical or imaging features to slow the accumulation of physical disability and reduce the frequency of clinical relapses.

19 Dec 2013

Blaze Bioscience to initiate first Phase 1 clinical study of BLZ-100 in patients with skin tumors

Blaze Bioscience, Inc. and its subsidiary, Blaze Bioscience Australia Pty Ltd, today announced the initiation of the first Phase 1 clinical study of the first Tumor Paint product candidate, BLZ-100. The study, titled "A Phase I Dose Escalation/Expansion Study of BLZ-100 Administered by Intravenous Injection in Adult Subjects with Skin Cancer," will enroll up to 30 patients with basal cell carcinoma, squamous cell carcinoma, or amelanotic melanoma.

19 Dec 2013

Royal Philips gets FDA approval for Spectral Breast Density Measurement Application

As breast density becomes a more recognized risk factor for breast cancer, Royal Philips today announced 510(k) clearance from the U.S. Food and Drug Administration for the Spectral Breast Density Measurement Application for its MicroDose SI full-field digital mammography system. The application is the first spectral Breast Density Measurement tool, meaning adipose (fat) and glandular tissue can be differentiated to accurately measure volumetric breast density.

19 Dec 2013

Neurocognitive abnormalities ‘fundamental’ to schizophrenia

Rare copy-number variants that confer a high risk for schizophrenia or autism are associated with impaired cognition in carriers without psychiatric disorders, researchers report in Nature.

19 Dec 2013

Researchers investigate several non-invasive methods for measuring intracranial pressure

Do you ever turn your world upside down by standing on your head? After a few minutes you might feel some pressure in your face and around your skull. This is because headstands invert the body's blood flow, pushing more blood toward your head.

19 Dec 2013

NUS scientists open possible new route for treatment of spinal muscular atrophy

A recent study led by scientists from the National University of Singapore (NUS) opens a possible new route for treatment of Spinal Muscular Atrophy (SMA), a devastating disease that is the most common genetic cause of infant death and also affects young adults.

18 Dec 2013

Brain's primary cortex generates efficiently compressed sensory information

Ten million bits - that's the information volume transmitted every second with every quick eye movement from the eye to the cerebrum. Researchers from the Ruhr-Universit-t Bochum (RUB) and the University of Osnabr-ck describe the way those data are processed by the primary visual cortex, the entry point for the visual information into the brain, in the journal "Cerebral Cortex".

18 Dec 2013

Studies suggest that stress-related disorders may be associated with hippocampal volume loss

Depression has been associated with reduced volume of the hippocampus in magnetic resonance imaging studies in humans. A new study just published in Biological Psychiatry now clarifies the cellular basis of these volumetric changes, which have been unclear until now.

18 Dec 2013

Navidea seeks FDA approval for marketing Lymphoseek Injection for SLN detection

Navidea Biopharmaceuticals, Inc., a biopharmaceutical company focused on precision diagnostic radiopharmaceuticals, announced today that it has submitted a Supplemental New Drug Application with the U.S. Food and Drug Administration seeking approval for the marketing and sale of Lymphoseek (technetium 99m tilmanocept) Injection for sentinel lymph node detection in patients with head and neck cancer, an indication for which Lymphoseek was also granted Fast Track designation earlier this month.

17 Dec 2013

Rich club disconnectivity may be ‘core’ schizophrenia feature

The impaired “rich club” connectivity observed in the brains of patients with schizophrenia is also present in their unaffected siblings, report researchers.

17 Dec 2013

Researchers use ATX-Red AR-2 as new imaging agent to illuminate tumors

Researchers from Echelon Biosciences, Inc. and collaborators from the University of Utah report the use of ATX-Red AR-2 as a new imaging agent that effectively illuminates tumors.

17 Dec 2013

Researchers confirm link between contrast agent and abnormalities on brain MRI

For the first time, researchers have confirmed an association between a common magnetic resonance imaging (MRI) contrast agent and abnormalities on brain MRI, according to a new study published online in the journal Radiology. The new study raises the possibility that a toxic component of the contrast agent may remain in the body long after administration.

17 Dec 2013

Alnylam initiates Phase II study with ALN-TTRsc for treatment of ATTR

Alnylam Pharmaceuticals, Inc., a leading RNAi therapeutics company, announced today that it has initiated a pilot Phase II study with ALN-TTRsc, a subcutaneously delivered RNAi therapeutic targeting the transthyretin gene in development for the treatment of TTR-mediated amyloidosis.

17 Dec 2013

New comprehensive edition for neurologists provides invaluable source of reference

A new comprehensive edition of a standard work, detailing and illustrating the organization, structure, function and connectivity of all individual brainstem nuclei. For neuroscientists and neurologists this atlas provides an invaluable and complete source of reference for both their scientific research and everyday clinical practice.

17 Dec 2013

Researchers identify potential biomarker to predict developmental problems in premature infants

Researchers have identified a potential biomarker for predicting whether a premature infant is at high risk for motor development problems, according to a study published online in the journal Radiology.

17 Dec 2013

New study aims to better understand brain aging and AD in adults with Down syndrome

To many, Down syndrome is a childhood condition. But improved health care means that individuals with DS now routinely reach age 50 or 60 years of age, sometimes beyond. However, if they live long enough, people with Down syndrome are almost certain to develop Alzheimer's disease.

17 Dec 2013

Researchers discover that unresponsive patients' brains may recognize photographs of their family, friends

Patients in a vegetative state are awake, breathe on their own, and seem to go in and out of sleep. But they do not respond to what is happening around them and exhibit no signs of conscious awareness. With communication impossible, friends and family are left wondering if the patients even know they are there.

17 Dec 2013

Imaging News and Research

New MRI approach can be important tool for diagnosing, tracking MS progression

New research assesses nanomedicine-based approaches for treating cancer

Researchers receive 3 Patient-Centered Outcomes Research Institute awards from PCORI

Australian Therapeutic Goods Administration approves Genzyme's Lemtrada for multiple sclerosis

Blaze Bioscience to initiate first Phase 1 clinical study of BLZ-100 in patients with skin tumors

Royal Philips gets FDA approval for Spectral Breast Density Measurement Application

Neurocognitive abnormalities ‘fundamental’ to schizophrenia

Researchers investigate several non-invasive methods for measuring intracranial pressure

NUS scientists open possible new route for treatment of spinal muscular atrophy

Brain's primary cortex generates efficiently compressed sensory information

Studies suggest that stress-related disorders may be associated with hippocampal volume loss

Navidea seeks FDA approval for marketing Lymphoseek Injection for SLN detection

Rich club disconnectivity may be ‘core’ schizophrenia feature

Researchers use ATX-Red AR-2 as new imaging agent to illuminate tumors

Researchers confirm link between contrast agent and abnormalities on brain MRI

Alnylam initiates Phase II study with ALN-TTRsc for treatment of ATTR

New comprehensive edition for neurologists provides invaluable source of reference

Researchers identify potential biomarker to predict developmental problems in premature infants

New study aims to better understand brain aging and AD in adults with Down syndrome

Researchers discover that unresponsive patients' brains may recognize photographs of their family, friends

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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