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Tumors use unique mechanism to switch on regulatory T cells for protection

Immunologists at St. Jude Children's Research Hospital have discovered that tumors use a unique mechanism to switch on regulatory T cells to protect themselves from attack by the immune system.

24 Feb 2021

SARS-CoV-2 does not infect the entire body in the same way, finds study

COVID-19, the disease caused by the pandemic coronavirus SARS-CoV-2, is primarily regarded as a respiratory infection. Yet the virus has also become known for affecting other parts of the body in ways not as well understood, sometimes with longer-term consequences, such as heart arrhythmia, fatigue and "brain fog."

24 Feb 2021

High-throughput genetic analysis can help dissect the mechanism of disease inheritance

Many genetic variants have been found to have a linkage with genetic diseases, but the understanding of their functional roles in causing diseases are still limited.

24 Feb 2021

AI-based 3D holographic microscopy found to be better at analyzing cancer immunotherapy

Live tracking and analyzing of the dynamics of chimeric antigen receptor (CAR) T-cells targeting cancer cells can open new avenues for the development of cancer immunotherapy.

24 Feb 2021

Study lays the groundwork for developing novel strategies to treat neurological diseases

A research team from the School of Life Sciences at The Chinese University of Hong Kong has recently discovered that SOX9 protein is an essential regulatory factor of choroid plexus function that ensures the correct composition of cerebrospinal fluid (CSF).

24 Feb 2021

Household odorant smell tests could help detect COVID-19, say study

Researchers at the Weizmann Institute of Science and other institutions developed a new tool to help detect COVID-19 infection. The team developed and tested a real-time tool to measure olfactory perception impairment by asking the participants to smell household odorants.

24 Feb 2021

GW team to play a role in Sanofi COVID-19 vaccine clinical trial

The George Washington University announced today its participation in a Sanofi COVID-19 vaccine clinical trial. GW was selected as one of approximately 25 sites in the United States to launch a phase 2 study for its adjuvanted recombinant protein-based COVID-19 vaccine candidate.

24 Feb 2021

Understanding Absolute Stoichiometry of Oligomeric Protein Complexes Using SEC-MALS

News-Med interviews .... about using SEC-MALS to characterize the native oligomeric state of Nap proteins and their complexes.

24 Feb 2021

In Vivo Probes for Detecting Inflammation Markers in Humans and Animals

News-Medical talks to Parry Hashemi about research on in vivo probes for detecting inflammation markers in humans and animals she will present at Pittcon.

From Pittcon 24 Feb 2021

Basigin does not facilitate SARS-CoV-2 entry, say researchers

Researchers investigated the significance of a transmembrane glycoprotein basigin, or CD147, as a host cell co-receptor required for the entry of SARS-CoV-2. The findings reveal that recombinant human basigin does not interact with full-length spike protein or spike RBD of SARS-CoV-2.

24 Feb 2021

A practical guide to critical parameters in acute care testing

The acute care testing handbook is a practical guide to critical parameters in acute care testing such as pO2, lactate and troponin.

From Radiometer Medical 24 Feb 2021

UK and South African SARS-CoV-2 variants show higher binding affinity to host cell receptor

New research by a team of scientists at Stanford University School of Medicine in the U.S. found that both the UK and South African SARS-CoV-2 variants display tighter binding to the ACE2 receptor.

24 Feb 2021

Researchers explore how N501Y mutation in SARS-CoV-2 increases viral transmissibility

Researchers at Erasmus University Medical Center in The Netherlands have explored how and why new variants of SARS-CoV-2 have exhibited heightened infectivity.

24 Feb 2021

Corticosteroid receptor inhibitor shows anti-SARS-CoV-2 activity in vivo

A team of researchers examined PT150, which is an allosteric modulator of androgen and glucocorticoid receptors, to assess whether it had any antiviral activity or immunomodulatory activity to decrease the hyperinflammatory response of SARS-CoV-2 infection.

24 Feb 2021

Study identifies another reason to add mushrooms to American diet

The second study published in as many months has identified another reason to add more mushrooms to the recommended American diet.

24 Feb 2021

Hyperactive immune system contributes to COVID-19 severity, lung damage

Researchers have pinpointed a helper T cell population in the lungs of patients with severe COVID-19 that may be central to the development of hyperinflammation, lung injury, and subsequent acute respiratory distress syndrome (ARDS) during disease.

24 Feb 2021

Study reveals how cancer cells escape death by lymphocytes

Immunotherapy continues to show exciting promise in more effectively combating several tumor types. Many current strategies focus on ensuring the efficient delivery of active cytotoxic cells directly to tumors.

24 Feb 2021

Microfluidic chip and AI-powered automated microscope help measure hemoglobin levels

One of the most performed medical diagnostic tests to ascertain the health of patients is a complete blood count, which typically includes an estimate of the hemoglobin concentration.

24 Feb 2021

Study: Abundance of iron can drive cancer cell death in neuroblastoma

Neuroblastoma is a cancer that develops in nerve tissue, most commonly in the glands around the kidneys. The gene MYCN is overexpressed in 20-25% of neuroblastoma, and MYCN-amplified neuroblastoma contributes to a considerable percentage of pediatric cancer-related deaths.

24 Feb 2021

New platform can help treat neurodegenerative diseases through regenerative medicine

Imagine if surgeons could transplant healthy neurons into patients living with neurodegenerative diseases or brain and spinal cord injuries.

24 Feb 2021

Protein C News and Research

Tumors use unique mechanism to switch on regulatory T cells for protection

SARS-CoV-2 does not infect the entire body in the same way, finds study

High-throughput genetic analysis can help dissect the mechanism of disease inheritance

AI-based 3D holographic microscopy found to be better at analyzing cancer immunotherapy

Study lays the groundwork for developing novel strategies to treat neurological diseases

Household odorant smell tests could help detect COVID-19, say study

GW team to play a role in Sanofi COVID-19 vaccine clinical trial

Understanding Absolute Stoichiometry of Oligomeric Protein Complexes Using SEC-MALS

In Vivo Probes for Detecting Inflammation Markers in Humans and Animals

Basigin does not facilitate SARS-CoV-2 entry, say researchers

A practical guide to critical parameters in acute care testing

UK and South African SARS-CoV-2 variants show higher binding affinity to host cell receptor

Researchers explore how N501Y mutation in SARS-CoV-2 increases viral transmissibility

Corticosteroid receptor inhibitor shows anti-SARS-CoV-2 activity in vivo

Study identifies another reason to add mushrooms to American diet

Hyperactive immune system contributes to COVID-19 severity, lung damage

Study reveals how cancer cells escape death by lymphocytes

Microfluidic chip and AI-powered automated microscope help measure hemoglobin levels

Study: Abundance of iron can drive cancer cell death in neuroblastoma

New platform can help treat neurodegenerative diseases through regenerative medicine

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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