Drugs News and Research

RSS

Municipal solid waste treatment systems could be a reservoir of antibiotic-resistance genes

Municipal solid waste is trash -- such as plastic, food scraps and lawn clippings -- that goes into garbage bins and doesn't get recycled.

25 Mar 2020

New molecular probes to study the behavior of opioid receptors

It could be an important step forward in the improvement of pain therapy: Thanks to newly developed molecular probes, the behavior of individual opioid receptors can now be studied in detail.

25 Mar 2020

Researchers uncover molecular link between trans fats and variety of disorders

Tohoku University researchers in Japan have uncovered a molecular link between some trans fats and a variety of disorders, including cardiovascular and neurodegenerative diseases.

25 Mar 2020

Why hoarding of hydroxychloroquine needs to stop

A family of old antimalarial drugs — including one that some patients rely on to treat their lupus or rheumatoid arthritis — is becoming harder to get in the United States, pharmacists say, partly because of remarks President Donald Trump has made, highlighting the drugs as a potential treatment for COVID-19.

25 Mar 2020

YAP signal pathway plays a vital role in the onset of head-and-neck cancer

Joint research between Kobe University and National Hospital Organization Kyushu Cancer Center has revealed that mice with mutations in the YAP signal pathway develop head-and-neck cancer over an extremely short period of time (world's fastest cancer onset mouse model), indicating that this pathway plays a crucial role in the onset of these cancers.

25 Mar 2020

New recommendations to tackle tuberculosis amid coronavirus crisis

The World Health Organization has today issued new recommendations to tackle tuberculosis, a respiratory disease, in the wake of coronavirus spreading across continents.

25 Mar 2020

Changes in surface sugarlike molecules help cancer cells to spread

Changes in a specific type of sugarlike molecule, or glycan, on the surface of cancer cells help them to spread into other tissues, according to researchers at the University of California, Davis. Published March 23 in Proceedings of the National Academy of Sciences, the work could lead to diagnostic tests and new therapies to slow or stop the spread of cancers.

25 Mar 2020

Researchers propose a stopgap measure to help Covid-19 patients in respiratory distress

Researchers at MIT and the University of Colorado at Denver have proposed a stopgap measure that they believe could help Covid-19 patients who are in acute respiratory distress.

24 Mar 2020

Clinical trial launched to investigate safety and efficacy of antiviral drug for COVID-19

Physician-scientists at four University of California Health medical centers -- UC San Diego Health, UC San Francisco, UC Irvine Health and UC Davis Health -- have begun recruiting participants for a Phase II clinical trial to investigate the safety and efficacy of treating adult patients with COVID-19 with remdesivir, an antiviral drug that has shown activity in animal models and human clinical trials of SARS-CoV, MERS-CoV, Ebola, Marburg and other viruses.

24 Mar 2020

OHDSI hosts COVID-19 virtual study-a-thon to generate real-world evidence

The Observational Health Data Sciences and Informatics international community will host a COVID-19 virtual study-a-thon this week (March 26-29) to inform healthcare decision-making in response to the current global pandemic.

24 Mar 2020

Multi-corneal barrier-on-a-chip device could help improve ophthalmic drug development

Researchers at Kyoto University's Institute for Integrated Cell-Material Sciences have developed a device that moves fluids over corneal cells similarly to the movement of tears over a blinking eye.

24 Mar 2020

Penn State engineers model genetic mutations causing drug resistance

Whether it is a drug-resistant strain of bacteria, or cancer cells that no longer react to the drugs intended to kill them, diverse mutations make cells resistant to chemicals, and "second generation" approaches are needed.

24 Mar 2020

Drebrin autoantibodies trigger epilepsy

Certain forms of epilepsy are accompanied by inflammation of important brain regions. Researchers at the University of Bonn have now identified a mechanism that explains this link.

24 Mar 2020

Senators who led pharma-friendly patent reform also prime targets for pharma cash

Early last year, as lawmakers vowed to curb rising drug prices, Sen. Thom Tillis was named chairman of the Senate Judiciary Committee's subcommittee on intellectual property rights, a committee that had not met since 2007.

24 Mar 2020

Projects to develop COVID-19 vaccines receive U.K. gov’t funding

The U.K. government backs six projects aimed to fight the coronavirus outbreak, promising $23 million (£20 million) in funding. The projects, including two focused on vaccination trials, will help fast track the development of a vaccine to stop the spread of the coronavirus, leading to the death of more than 16,500 people across the globe.

24 Mar 2020

Coronavirus cases approaching the 400,000 mark

Recent updates show a rapidly spiking incidence rate for the novel coronavirus disease COVID-19 that has already affected well over 380,000 people the world over, killing well over 16,000 of them. In a bid to arrest viral spread in its tracks, shops and other establishments have stopped their physical operations, but deaths continue to increase.

24 Mar 2020

Huge WHO trial of COVID-19 therapies begins

As the world reels from the devastating impact and the looming threat of the novel coronavirus COVID-19, researchers around the globe are racing to find a cure that will reduce symptom severity and reverse the course of the disease, freeing up more hospital space and making it possible to treat more of the severely affected cases.

24 Mar 2020