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Avantor launches new single-use, closed-system sampling solution to reduce contamination risks during bioprocessing

Avantor, Inc., a leading global provider of mission-critical products and services to customers in the life sciences and advanced technologies and applied materials industries, launched its new OmniTop Sample Tubes Adjustable Volume Sampling System that lowers contamination risk and greatly reduces volume loss by enabling technicians to collect an exact amount of media needed to perform routine sampling in bioprocessing operations.

From Avantor 5 May 2020

Scientists receive $12-million grant to explore molecular mechanisms of heart injury and repair

Heart disease is a leading cause of death worldwide. But significant disparities exist in the incidence and severity of heart disease, particularly between men and women, and major barriers remain for the successful long-term care of heart disease patients.

5 May 2020

Hydroxychloroquine shown to slow recovery for COVID-19 patients

As researchers try to piece together a therapeutic strategy against the ongoing COVID-19 pandemic, a recent retrospective study from Cleveland Clinic Abu Dhabi, assessed the Hydroxychloroquine's efficacy in increasing SARS-CoV-2 viral clearance, finding that it appeared to significantly slow viral clearance in mild to moderately ill COVID-19 patients.

5 May 2020

COVID-19 progression linked to B cell activation

The disease course of COVID-19 is diverse, ranging from asymptomatic to fatal respiratory failure. Scientists have been working to uncover the immunological reasons behind this heterogeneity. A recent study on B cells, published on the preprint server medRxiv in April 2020, shows that extrafollicular B cells could be a marker of severe infection in the early stages, predicting the need for earlier immunomodulatory therapy.

4 May 2020

Activation of estrogen receptor can impede growth of pancreatic cancer cells

Activating the G protein-coupled estrogen receptor - a receptor found on the surface of many normal and cancer tissues - has been shown to stop pancreatic cancer from growing, but may also make tumors more visible to the immune system and thus more susceptible to modern immunotherapy.

4 May 2020

New recommendations for treating the most critical COVID-19 patients

As the number of coronavirus cases continues to rise and the deaths mount, the American Society for Artificial Internal Organs has drafted a set of recommendations for health care workers on the front lines, to help them make decisions on how to treat the most critical patients, those with severe lung or heart failure

4 May 2020

Wyss Institute and Cytosurge collaborate to improve CRISPR multiplexing

Today, the Wyss Institute for Biologically Inspired Engineering at Harvard University and Cytosurge AG, a company manufacturing unique high-precision nanotechnology instruments, announced that they will collaboratively investigate CRISPR-based approaches to more effectively introduce multiple edits into the genome of single cells, while minimizing CRISPR-related toxicity.

4 May 2020

Study defines new starting points for therapy and vaccine research on coronavirus

The SARS coronavirus 2 (SARS-CoV-2) infects lung cells and is responsible for the COVID-19 pandemic. The viral spike protein mediates entry of the virus into host cells and harbors an unusual activation sequence.

4 May 2020

AHA calls for specialized care for pregnant women with cardiovascular conditions

Women with cardiovascular conditions should be cared for during pregnancy by a cardio-obstetrics team or health care providers experienced in high-risk pregnancies to provide specialized maternity care for the mother and fetus, according to a new American Heart Association scientific statement, Cardiovascular Considerations in Caring for Pregnant Patients, published today in the Association's flagship journal Circulation.

4 May 2020

FDA approves SFU professor's invention to wean COVID-19 patients from ventilators

Simon Fraser University professor Andy Hoffer hopes the SFU spinoff company he founded, Lungpacer Medical Inc., will help save the lives of COVID-19 patients using mechanical ventilators--and get them off more quickly, so that more ventilators can be available for all critically ill patients.

4 May 2020

RA patients enrolled in Medicare plan face significant cost exposure on specialty drugs

After a sharp drop in out-of-pocket costs between 2010 and 2011, Medicare patients who use specialty biologic medications for rheumatoid arthritis have seen higher out-of-pocket spending for those same drugs because of gradual price increases, a new study in the Journal of the American Medical Association Open finds.

4 May 2020

Study: Unique glucose-sensing neurons in the brain prevent severe hypoglycemia

Low blood sugar levels, known as hypoglycemia, can be a life-threatening situation, especially for people with type 1 diabetes who rely on intensive insulin therapy to prevent blood sugar from going too high.

4 May 2020

Hydroxychloroquine combined with azithromycin and abnormal heart rhythms in COVID-19 patients

A new study shows that the initially lauded combination of drugs against COVID-19 - Hydroxychloroquine and Chloroquine combined with azithromycin, could lead to abnormal and life-threatening heart rhythms. In patients hospitalized with the novel coronavirus infection or SARS CoV-2, this combination can lead to prolonged QT interval as can be detected on ECG.

3 May 2020

Anti-malarial drug use for COVID-19 associated with increased risk of cardiac arrhythmias

Since the World Health Organization declared COVID-19 a Public Health Concern of Global Interest on January 30, more than one million have tested positive for the illness in the United States, and more than 62,000 have died.

3 May 2020

Real-time monitoring of biochemical processes on DNA using infrared spectroscopy

DNA damage in general and DNA strand breaks in particular occur every day in all cells of the human body.

3 May 2020

Research reveals mechanism underlying Parkinson's dyskinesia

Many people with Parkinson's disease eventually develop debilitating movements called dyskinesia, a side effect of their much-needed dopamine replacement medication.

3 May 2020

Cancer patients with COVID-19 more likely to die from the disease

People with cancer who develop COVID-19 are much more likely to die from the disease than those without cancer, according to physician-researchers at Montefiore Health System and Albert Einstein College of Medicine.

2 May 2020

Lipo-ImmunoTech receives grant to develop novel adoptive cell therapy technology for cancer

Lipo-ImmunoTech, LLC, a startup based in Charleston, South Carolina, recently received a Phase I Small Business Technology Transfer grant of just over $224,000 to continue to develop its novel adoptive cell therapy technology for cancer.

2 May 2020

Study finds Lin28 as promising therapeutic target for central nervous system injuries

Like power lines in an electrical grid, long wiry projections that grow outward from neurons - structures known as axons - form interconnected communication networks that run from the brain to all parts of the body.

2 May 2020

Combination of schizophrenia drug and radiation shows promise in treating glioblastoma

Researchers at the UCLA Jonsson Comprehensive Cancer Center and colleagues have found that adding a drug once commonly used to treat schizophrenia to traditional radiation therapy helped improve overall survival in mice with glioblastoma, one of the deadliest and most difficult-to-treat brain tumors.

2 May 2020

Therapy News and Research

Avantor launches new single-use, closed-system sampling solution to reduce contamination risks during bioprocessing

Scientists receive $12-million grant to explore molecular mechanisms of heart injury and repair

Hydroxychloroquine shown to slow recovery for COVID-19 patients

COVID-19 progression linked to B cell activation

Activation of estrogen receptor can impede growth of pancreatic cancer cells

New recommendations for treating the most critical COVID-19 patients

Wyss Institute and Cytosurge collaborate to improve CRISPR multiplexing

Study defines new starting points for therapy and vaccine research on coronavirus

AHA calls for specialized care for pregnant women with cardiovascular conditions

FDA approves SFU professor's invention to wean COVID-19 patients from ventilators

RA patients enrolled in Medicare plan face significant cost exposure on specialty drugs

Study: Unique glucose-sensing neurons in the brain prevent severe hypoglycemia

Hydroxychloroquine combined with azithromycin and abnormal heart rhythms in COVID-19 patients

Anti-malarial drug use for COVID-19 associated with increased risk of cardiac arrhythmias

Real-time monitoring of biochemical processes on DNA using infrared spectroscopy

Research reveals mechanism underlying Parkinson's dyskinesia

Cancer patients with COVID-19 more likely to die from the disease

Lipo-ImmunoTech receives grant to develop novel adoptive cell therapy technology for cancer

Study finds Lin28 as promising therapeutic target for central nervous system injuries

Combination of schizophrenia drug and radiation shows promise in treating glioblastoma

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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