Immune System News and Research

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Researchers show importance of DNA damage in fine tuning of innate immune system

For the first time scientists from Umeå University show the importance of DNA damage in fine tuning of our innate immune system and hence the ability to mount the optimal inflammatory response to infections and other biological dangers.

18 Feb 2015

Corticosteroids decrease treatment failure among patients with community-acquired pneumonia

Among patients with severe community-acquired pneumonia and high initial inflammatory response, the use of the corticosteroid methylprednisolone decreased treatment failure, compared with placebo, according to a study in the February 17 issue of JAMA.

18 Feb 2015

Trinity scientists reveal new marvel molecule that can block key process in inflammatory diseases

Scientists at Trinity College Dublin have uncovered a marvel molecule that blocks a key driver of inflammatory diseases. The finding could meet a major unmet clinical need by inspiring new non-invasive treatments for arthritis, multiple sclerosis and Muckle-Wells syndrome, among a myriad of other inflammatory diseases.

18 Feb 2015

CAMH scientists discover potential new approach to treat multiple sclerosis

Scientists at the Centre for Addiction and Mental Health have discovered a promising new approach to treat multiple sclerosis (MS). In a new study, they've identified a previously unknown change in the spinal cord related to MS, and a way to alter this change to reduce the nerve cell damage that occurs with the disease.

18 Feb 2015

TNF signaling molecule triggers Crohn's disease, ulcerative colitis

Cells lining the intestinal tract form a critical barrier, protecting our bodies from the billions of bacteria living in the gut. Breaches in this barrier are driven largely by a single signaling molecule called tumor necrosis factor (TNF), elevated amounts of which are associated with inflammatory bowel diseases like Crohn's disease and ulcerative colitis.

17 Feb 2015

Saliva test holds promise to diagnose autism spectrum disorder in children

A spit test may one day be able to diagnose autism according to researchers at Clarkson University and the State University of New York at Plattsburgh.

17 Feb 2015

Study shows link between autoimmune diseases and gene regulatory elements

Investigators with the National Institutes of Health have discovered the genomic switches of a blood cell key to regulating the human immune system.

17 Feb 2015

BHB compound produced during dieting blocks part of immune system involved in inflammatory disorders

Researchers at Yale School of Medicine have found that a compound produced by the body when dieting or fasting can block a part of the immune system involved in several inflammatory disorders such as type 2 diabetes, atherosclerosis, and Alzheimer's disease.

17 Feb 2015

Winter weather may cause vitamin D deficiency

Residents of snowy, northern U.S. cities are at risk of vitamin D deficiency and worse, may not even know it.

16 Feb 2015

Discovery offers much needed information about how virulent insect-borne diseases cause infection

For decades, scientists have thought the bacteria that cause the bubonic plague hijack host cells at the site of a fleabite and are then taken to the lymph nodes, where the bacteria multiply and trigger severe disease. But UNC School of Medicine researchers discovered that this accepted theory is off base. The bacteria do not use host cells; they traffic to lymph nodes on their own and not in great numbers.

16 Feb 2015

KU Leuven researchers find aggressive form of HIV in Cuba

Engaging in unprotected sex with multiple partners increases the risk of contracting multiple strains of HIV, the virus that causes AIDS. Once inside a host, these strains can recombine into a new variant of the virus. One such recombinant variant observed in patients in Cuba appears to be much more aggressive than other known forms of HIV.

16 Feb 2015

AARDA releases white paper to educate its members, patient community about biosimilar medicines

The American Autoimmune Related Diseases Association, a national nonprofit health organization dedicated to increasing awareness of autoimmune diseases, today issued a white paper to educate its membership and the patient community about biosimilar medicines after a survey found most patients were generally unaware of this new category of medicines which may soon be approved in the U.S.

16 Feb 2015

Findings show how human bodies restrict production of IgE to prevent allergic reaction

Scientists from the CNRS, INSERM and Université de Limoges, working in the Laboratoire Contrôle de la Réponse Immune B et Lymphoproliférations (CNRS/Université de Limoges) have demonstrated that the production of type E immunoglobulins (IgE) by B lymphocytes induces a loss in their mobility and the initiation of cell death mechanisms.

16 Feb 2015

Research finding could lead to new therapeutic target for treating hypertension in males

Higher levels of a "danger" molecule may be one reason males tend to become hypertensive earlier and more severely than females, scientists say.

16 Feb 2015

Researchers develop novel strategy in fight against cancer

A team of researchers led by Associate Professor Caroline Lee from the Yong Loo Lin School of Medicine at the National University of Singapore, in collaboration with Associate Professor Song Jianxing of the Department of Biological Sciences at the NUS Faculty of Science, has developed a novel strategy in the fight against cancer.

15 Feb 2015

UT Southwestern researchers identify common signaling mechanism that controls immune system

UT Southwestern Medical Center researchers have identified a common signaling mechanism to produce interferon - one of the main proteins used to signal the immune system when the body needs to defend itself against a virus, tumor, or other diseases.

15 Feb 2015

Immune system exploits flu virus' dependence on host's machinery

Viruses are masters of outsourcing, entrusting their fundamental function - reproduction - to the host cells they infect. But it turns out this highly economical approach also creates vulnerability.

13 Feb 2015

Doctor's Best adds three new sports nutrition powders to its science-based supplement portfolio

Doctor's Best has introduced three new sports nutrition powders – Creatine, Branched Chain Amino Acids (BCAA) and L-Arginine - into its science-based supplement portfolio.

13 Feb 2015

Stem cell transplants more effective than mitoxantrone drug for people with severe multiple sclerosis

Stem cell transplants may be more effective than the drug mitoxantrone for people with severe cases of multiple sclerosis (MS), according to a new study published in the February 11, 2015, online issue of Neurology, the medical journal of the American Academy of Neurology.

12 Feb 2015

InterveXion receives federal grants for development of drug therapies to treat methamphetamine users

A University of Arkansas for Medical Sciences BioVentures startup company, InterveXion Therapeutics LLC, has received two federal grants totaling $14.5 million for development of drug therapies that can help methamphetamine drug abusers break their addiction.

12 Feb 2015

Immune System News and Research

Researchers show importance of DNA damage in fine tuning of innate immune system

Corticosteroids decrease treatment failure among patients with community-acquired pneumonia

Trinity scientists reveal new marvel molecule that can block key process in inflammatory diseases

CAMH scientists discover potential new approach to treat multiple sclerosis

TNF signaling molecule triggers Crohn's disease, ulcerative colitis

Saliva test holds promise to diagnose autism spectrum disorder in children

Study shows link between autoimmune diseases and gene regulatory elements

BHB compound produced during dieting blocks part of immune system involved in inflammatory disorders

Winter weather may cause vitamin D deficiency

Discovery offers much needed information about how virulent insect-borne diseases cause infection

KU Leuven researchers find aggressive form of HIV in Cuba

AARDA releases white paper to educate its members, patient community about biosimilar medicines

Findings show how human bodies restrict production of IgE to prevent allergic reaction

Research finding could lead to new therapeutic target for treating hypertension in males

Researchers develop novel strategy in fight against cancer

UT Southwestern researchers identify common signaling mechanism that controls immune system

Immune system exploits flu virus' dependence on host's machinery

Doctor's Best adds three new sports nutrition powders to its science-based supplement portfolio

Stem cell transplants more effective than mitoxantrone drug for people with severe multiple sclerosis

InterveXion receives federal grants for development of drug therapies to treat methamphetamine users

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