Drug Discovery News and Research

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The drug discovery process begins with recognizing a disease or clinical condition in which there is a lack of adequate medical treatment. Once a potential drug has been identified, pre-clinical research can begin. This process includes several stages; the first of which involves identifying and validating the prospective drug’s target through assay development, high throughput screening, hit identification and finally, lead optimization. Once the pre-clinical process is complete, the newly synthesized drug candidate is selected for future clinical development.

Yokogawa Develops Single Cellome System SS2000 for Subcellular Sampling

A single-cell analysis solution that revolutionizes efficiency in drug discovery research by automating the collection of specific cells and intracellular components.

From Yokogawa Life Science 9 Dec 2021

The antiviral potential of 4′-fluorouridine as an oral treatment against RSV and SARS-CoV-2

New research reports 4’-Fluorouridine (4′-FlU) as an oral antiviral against RSV and SARS-CoV-2.

7 Dec 2021

A promising new therapeutic target for kidney disease

Despite nearly two million people dying of acute kidney injury every year, and tens of millions more needing treatment, no effective drug treatment for the condition is available.

7 Dec 2021

Metrion Biosciences expands ion channel drug discovery service capabilities and in-house expertise

Metrion today announced it has expanded its capabilities and expertise through the addition of automated low volume liquid handling capability.

From Metrion Biosciences Limited 7 Dec 2021

New protein variant underlies the ability of gastric cancers to resist chemotherapy

A new protein variant underlies the ability of gastric cancers to resist an otherwise effective family of chemotherapy drugs, according to a study by a multidisciplinary team at Weill Cornell Medicine. The results suggest a treatment strategy that could improve the prognoses of many patients with cancer.

6 Dec 2021

Cataract surgery associated with lower risk of dementia

Cataracts affect most older adults at risk for dementia, and now researchers are finding strong evidence that cataract surgery is associated with a lower risk of developing dementia.

6 Dec 2021

Study uncovers a promising drug candidate to minimize dyskinesia in Parkinson's patients

A new study from Texas Biomedical Research Institute (Texas Biomed) and collaborators has identified a promising drug candidate to minimize uncontrolled, erratic muscle movements, called dyskinesia, associated with Parkinson's disease.

1 Dec 2021

Custom Biofluid & Tissue Procurement Service

Global provider of human and animal biospecimens - AMSBIO offers a custom procurement service enabling researchers to source specific biofluid and tissue samples which are not already available in their extensive biorepository.

From AMS Biotechnology 1 Dec 2021

Novel anti-inflammatory drug target identified by CRISPR

In this interview, News-Medical speaks to Dr. Jeffrey Rathmell about his recent research into how metabolic pathways impact immune function.

1 Dec 2021

SPORE-funded Kidney Cancer Program at UT Southwestern reports wide array of tumor models to date

Funded by a Specialized Program of Research Excellence award from the National Cancer Institute (NCI), the Kidney Cancer Program at UT Southwestern's Harold C. Simmons Comprehensive Cancer Center reports the largest and most diverse catalog of kidney cancer tumor models to date.

29 Nov 2021

Novel method enables deeper analysis of endocrine disrupting chemicals' impact on gene expression

When something disrupts hormone binding to the receptor, such as environmental compounds or pollutants, called endocrine disrupting chemicals (EDCs), the results can be harmful and, in some cases, lead to certain forms of cancer.

24 Nov 2021

Experimental compound reduces diabetic complications in mice

An experimental compound reduced complications of type 1 and type 2 diabetes in mice—not by lowering blood sugar—but by countering its consequences of cell death, inflammation, and organ damage.

24 Nov 2021

Oral Hsp90 inhibitor SNX-5422 interferes with replication machinery of SARS-CoV-2

A new study evaluates the efficacy of SNX-5422 as a post-exposure prophylactic treatment.

23 Nov 2021

How the new In-Vitro Diagnostics Regulations are affecting the life sciences landscape

In this interview, News-Medical talks to Laura Nea, Vice President of Quality and Regulatory Management at Tecan, about the upcoming changes to the regulations surrounding in-vitro diagnostics and how they might affect the life sciences landscape.

From Tecan 23 Nov 2021

Monitoring cellular metabolism for NAFLD/NASH liver disease research

In this interview, Jolanta Vidugiriene, a Senior Research Scientist at Promega Corporation, talks to News-Medical about tools for studying metabolism in NAFLD/NASH research.

From Promega Corporation 22 Nov 2021

Powerful database focuses on disarming deadly superbugs

Disarming superbugs that can cause deadly infections is the focus of a powerful database now housed at The University of Queensland.

21 Nov 2021

Human Proteoform Project aims to define the entire collection of proteins in the body

Now that the Human Genome Project has officially wrapped, an international team of researchers will map the entire collection of proteins in the human body.

21 Nov 2021

Weill Cornell Medicine receives $1.27 million DoD grant to develop treatment for rare eye condition

Weill Cornell Medicine has received a $1.27 million grant from the United States Department of Defense (DoD) to develop treatment for a rare but devastating eye condition largely affecting military personnel who suffer traumatic eye injuries in combat.

20 Nov 2021

How to achieve fast, accurate and reliable quantitation of AAV serotypes

In this interview, News-Medical talks to Indrani Chakraborty from GatorBio about how they have achieved accurate and reliable quantitation of AAV serotypes.

From Gator Bio, Inc. 19 Nov 2021

The Power of Digitalization in the Life Sciences and Diagnostics Sectors

In this interview, News-Medical talks to Frank Buescher and Wael Yared about the increasing digitalization of the life sciences and diagnostics sectors and the possibilities this entails.

From Tecan 19 Nov 2021

Drug Discovery News and Research

Further Reading

Yokogawa Develops Single Cellome System SS2000 for Subcellular Sampling

The antiviral potential of 4′-fluorouridine as an oral treatment against RSV and SARS-CoV-2

A promising new therapeutic target for kidney disease

Metrion Biosciences expands ion channel drug discovery service capabilities and in-house expertise

New protein variant underlies the ability of gastric cancers to resist chemotherapy

Cataract surgery associated with lower risk of dementia

Study uncovers a promising drug candidate to minimize dyskinesia in Parkinson's patients

Custom Biofluid & Tissue Procurement Service

Novel anti-inflammatory drug target identified by CRISPR

SPORE-funded Kidney Cancer Program at UT Southwestern reports wide array of tumor models to date

Novel method enables deeper analysis of endocrine disrupting chemicals' impact on gene expression

Experimental compound reduces diabetic complications in mice

Oral Hsp90 inhibitor SNX-5422 interferes with replication machinery of SARS-CoV-2

How the new In-Vitro Diagnostics Regulations are affecting the life sciences landscape

Monitoring cellular metabolism for NAFLD/NASH liver disease research

Powerful database focuses on disarming deadly superbugs

Human Proteoform Project aims to define the entire collection of proteins in the body

Weill Cornell Medicine receives $1.27 million DoD grant to develop treatment for rare eye condition

How to achieve fast, accurate and reliable quantitation of AAV serotypes

The Power of Digitalization in the Life Sciences and Diagnostics Sectors

New Approach Methodologies, the 3Rs and Multimodal Imaging in Preclinical Research - eBook eBook

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