Fibrosis News and Research

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Fibrosis is the growth of fibrous tissue.

Researchers develop multi-channel recording device for lung sound analysis

A multi-channel recording device developed at TU Graz for pathological lung sounds and associated automatic lung sound analysis could support existing screening methods for early detection of, for example, Covid-19 infections. This now requires clinical data and interdisciplinary collaboration.

7 Dec 2020

Lung tissue analysis reveals promising molecular target to ameliorate pulmonary fibrosis

An analysis of lung tissues from patients with different types of pulmonary fibrosis - including cases triggered by COVID-19 - has revealed a promising molecular target to ameliorate the chronic and irreversible disease.

5 Dec 2020

Scientists report the first map of molecular responses of human lung cells to SARS-CoV-2 infection

In a multi-group collaborative involving the National Emerging Infectious Disease Laboratories (NEIDL), the Center for Regenerative Medicine (CReM), and the Center for Network Systems Biology (CNSB), scientists have reported the first map of the molecular responses of human lung cells to infection by SARS-CoV-2.

2 Dec 2020

NMR-based diagnostic tool could be used to detect fatty liver disease or liver fibrosis

About 25 percent of the U.S. population suffers from fatty liver disease, a condition that can lead to fibrosis of the liver and, eventually, liver failure.

2 Dec 2020

Researchers develop telomerase gene therapy for treating different pathologies

After several years of research and many joint scientific publications, molecular biologists Maria Blasco (National Cancer Research Centre, CNIO) and Fàtima Bosch (Universitat Autònoma de Barcelona, UAB) have developed a telomerase gene therapy for the treatment of different pathologies related to shortening telomeres and, therefore, ageing.

2 Dec 2020

Research provides deeper insight into the pathogenesis of sclerodermatous chronic GVHD

Occasionally, following a transplant procedure, the donor's immune cells recognize the recipient's tissues as foreign and trigger a multisystem disorder called graft-versus-host disease (GVHD).

2 Dec 2020

Study provides new insights into an untreatable form of childhood-onset dementia

Is the eye a window to the brain in Sanfilippo syndrome, an untreatable form of childhood-onset dementia, Australian researchers ask in a new publication.

2 Dec 2020

Repurposed mouse model sheds light on spectrum of COVID-19 disease symptoms

A repurposed mouse model can develop symptoms of both severe COVID-19 (lung damage, blood clots, abnormal blood vessels, and death) and also of milder disease, including loss of the sense of smell, according to a recent University of Iowa study published in Nature.

1 Dec 2020

New method could help determine the most appropriate treatment for HIV patients

A team co-led by a scientist at the University of California, Riverside, has developed a method to study how HIV mutates to escape the immune system in multiple individuals, which could inform HIV vaccine design.

30 Nov 2020

Mild electrical stimulation with heat shock exerts protective effect against nephrotic syndrome

A research team from Kumamoto University in Japan has found that the combination of weak pulsed electrical current and heat exerts anti-inflammatory and anti-fibrotic effects in the kidneys, as well as a protective effect against nephrotic syndrome (NS) by inhibiting apoptosis (cell death) of kidney cells.

30 Nov 2020

Systemic inflammation increases over various stages of liver cirrhosis, shows study

Patients with liver cirrhosis display a wide range of clinical symptoms. A prospective study conducted by MedUni Vienna has now shown that blood levels of biomarkers for systemic inflammation increase over the various stages of the disease and can predict the development of complications, even in previously asymptomatic patients.

30 Nov 2020

Researchers discover blood gene signatures that can predict COVID-19 severity

A team of scientists from the University of Chicago, NCH Healthcare System and the University of South Florida has identified a specific set of genes associated with a poor prognosis of COVID-19.

26 Nov 2020

Fruit fly study reveals the effects of microgravity on the heart

Scientists at Sanford Burnham Prebys Medical Discovery Institute have shown that fruit flies that spent several weeks on the International Space Station (ISS)—about half of their lives—experienced profound structural and biochemical changes to their hearts.

25 Nov 2020

New therapy for flu may prove effective against many other pathogenic virus infections

A new therapy for influenza virus infections that may also prove effective against many other pathogenic virus infections, including HIV and COVID-19, has been developed by Purdue University scientists.

24 Nov 2020

Potential treatment could reduce heart failure after a significant heart attack

While there are therapies to aid in overall heart health, there are very few preventative therapies for heart failure after a significant heart attack, a serious condition that has a very significant mortality.

24 Nov 2020

New therapy developed for flu infections may also prove effective against HIV, COVID-19

24 Nov 2020

Antimicrobial found in soaps worsens fatty liver disease in mice

University of California San Diego School of Medicine researchers found evidence that triclosan -- an antimicrobial found in many soaps and other household items -- worsens fatty liver disease in mice fed a high-fat diet.

23 Nov 2020

New model provides better understanding of lung infections in patients with cystic fibrosis

For young people with cystic fibrosis, lung infection with Staphylococcus aureus, MRSA, is common and is treated with antibiotics in the hope that this will prevent a decline in lung function.

19 Nov 2020

Immune mechanism responsible for adverse inflammatory reactions after stem cell transplant identified

In the treatment of leukemia, stem cell transplantation subsequent to chemotherapy and radiation can often engender severe adverse inflammatory reactions - especially in the skin or in the gut, since these so-called barrier organs are more frequently affected.

19 Nov 2020

LOX plays a number of key roles in promoting skin and organ fibrosis in scleroderma

A team of researchers at the Medical University of South Carolina (MUSC) has found that the molecule lysyl oxidase (LOX) plays a number of important roles in promoting skin and organ fibrosis in scleroderma, a connective tissue disorder.

17 Nov 2020

Fibrosis News and Research

Further Reading

Researchers develop multi-channel recording device for lung sound analysis

Lung tissue analysis reveals promising molecular target to ameliorate pulmonary fibrosis

Scientists report the first map of molecular responses of human lung cells to SARS-CoV-2 infection

NMR-based diagnostic tool could be used to detect fatty liver disease or liver fibrosis

Researchers develop telomerase gene therapy for treating different pathologies

Research provides deeper insight into the pathogenesis of sclerodermatous chronic GVHD

Study provides new insights into an untreatable form of childhood-onset dementia

Repurposed mouse model sheds light on spectrum of COVID-19 disease symptoms

New method could help determine the most appropriate treatment for HIV patients

Mild electrical stimulation with heat shock exerts protective effect against nephrotic syndrome

Systemic inflammation increases over various stages of liver cirrhosis, shows study

Researchers discover blood gene signatures that can predict COVID-19 severity

Fruit fly study reveals the effects of microgravity on the heart

New therapy for flu may prove effective against many other pathogenic virus infections

Potential treatment could reduce heart failure after a significant heart attack

New therapy developed for flu infections may also prove effective against HIV, COVID-19

Antimicrobial found in soaps worsens fatty liver disease in mice

New model provides better understanding of lung infections in patients with cystic fibrosis

Immune mechanism responsible for adverse inflammatory reactions after stem cell transplant identified

LOX plays a number of key roles in promoting skin and organ fibrosis in scleroderma

Industry Focus eBook - Cell biology (5th edition) eBook

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