Gene Expression News and Research

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Gene Expression is the process by which a gene gets turned on in a cell to make RNA and proteins. Gene expression may be measured by looking at the RNA, or the protein made from the RNA, or what the protein does in a cell.

UTA biology student wins award for research on antimicrobial drug resistance

A senior biology student at The University of Texas at Arlington recently earned an award for her research about antimicrobial drug resistance.

29 Nov 2023

New insights into evolution of the “little brain”

The evolution of higher cognitive functions in human beings has so far mostly been linked to the expansion of the neocortex – a region of the brain that is responsible, inter alia, for conscious thought, movement and sensory perception.

29 Nov 2023

Study uncovers cell signaling pathway that regulates melanoma brain metastasis

Melanoma is the deadliest form of skin cancer because of its ability to quickly grow and spread throughout the body.

29 Nov 2023

Mechanically reprogrammed connective tissue cells can promote wound healing

Researchers at PSI and ETH Zurich have taken connective tissue cells that have been mechanically reprogrammed to resemble stem cells and transplanted them into damaged skin.

29 Nov 2023

Researchers introduce CRISPR-mediated genome and cancer shredding as a conceptual paradigm to treat recurrent gliomas

Researchers demonstrated clustered regularly interspersed short palindromic repeats (CRISPR)-mediated elimination of glioblastoma (GBM) cells.

29 Nov 2023

Decoding anxiety: Study reveals brain's role in behavioral inhibition risks

Researchers in the U.S. used non-human primate models to explore the molecular mechanisms and neural systems behind behavioral inhibition, a key risk factor for anxiety disorders. The study identified molecular systems in the posterior orbitofrontal cortex linked to variations in anxious temperament, offering potential targets for treating anxiety disorders.

28 Nov 2023

New heart organoid model could revolutionize drug development and toxicology studies

Heart disease kills 18 million people each year, but the development of new therapies faces a bottleneck: no physiological model of the entire human heart exists – so far.

28 Nov 2023

DNA methylation: A key player in gene expression variation and disease manifestation

Professor Asaf Hellman and his research team at the Hebrew University-Hadassah Medical School have unveiled new findings in the realm of methylation-directed regulatory networks.

27 Nov 2023

Genetic mutation in OXR1 gene linked to brain development issues

Study investigates the effects of a loss-of-function mutation in the OXR1 gene on neurodevelopment and cellular functions in the human brain. The research shows that OXR1 deficiency impairs neural differentiation, increases sensitivity to oxidative stress, and alters histone methylation, impacting brain development and potentially contributing to neurological disorders.

27 Nov 2023

Scientists discover master regulator gene for fat storage

We all know that weight gain and weight loss are not as simple as "calories in, calories out," given that countless factors affect body weight.

27 Nov 2023

Fiber-free diet key to treating childhood Crohn's disease, new study finds

Research reveals how a fiber-free diet in Exclusive Enteral Nutrition (EEN) helps treat Crohn's disease in children by affecting the intestinal pathobiont Mucispirillum schaedleri. It shows that this diet alters gut microbiota, reducing Mucispirillum's pathogenicity and aiding in managing colitis.

26 Nov 2023

Pomegranate's power: Studies show promise in cardiovascular and diabetic health

Researchers reviewed existing data on the bio-modulatory effects of pomegranate (Punica granatum l., PG) polyphenols on metabolic disorders.

24 Nov 2023

Gene therapy could reverse symptoms of rare, hereditary DOOR syndrome

A lot of research has been done over many decades on diseases that are widespread in large parts of the population, such as cancer and heart disease. As a result, treatment methods have improved enormously thanks to long-term research efforts on diseases that affect many people.

23 Nov 2023

Exploring the impact of soy isoflavones in prostate cancer therapy

The cellular mechanisms of soy isoflavones, genistein, daidzein, and equol.

23 Nov 2023

Scientists uncover key to enhancing cancer-killing T cells

T cells are the key immune system component involved in killing cancer. Tumors produce signals that turn off these T cells, partially by forcing them to progressively differentiate (mature) into a hypofunctional state known as exhaustion.

21 Nov 2023

Sex-specific brain immunometabolism differences may underlie increased Alzheimer's risk in women

Cleveland Clinic researchers analyzed genes and brain tissue of patients with Alzheimer's and found that differences in brain immunometabolism – the interactions between the immune system and the ways cells create energy – may contribute to women's increased risk for the disease and its severity.

21 Nov 2023

New study links DNA methylation in GLP1R gene to obesity without metabolic disorders

The study investigates the role of epigenetic changes in GLP1R gene polymorphisms on metabolically healthy obesity (MHO), revealing that apart from genetic variations, DNA methylation significantly influences the occurrence of MHO.

20 Nov 2023

Study highlights glycolysis as a potential therapeutic target to combat Mycobacterium tuberculosis

It has been uncertain how Mycobacterium tuberculosis deflects the immune response in humans, though evidence has pointed to host immunometabolism - the intrinsic link between metabolism in immune cells and their immune function.

20 Nov 2023

Scientists uncover "genomic tug of war" that influences chemotherapy's effectiveness

Some patients with myelodysplastic syndromes, like acute myeloid leukemia, benefit from a chemotherapy drug called decitabine that stunts cancer growth. But many others are resistant to decatibine's effects or become resistant over time.

16 Nov 2023

New insights into how cells maintain their identity over generations

Every cell in the human body contains the same genetic instructions, encoded in its DNA. However, out of about 30,000 genes, each cell expresses only those genes that it needs to become a nerve cell, immune cell, or any of the other hundreds of cell types in the body.

16 Nov 2023