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Anti-inflammatory drug shown to promote cardiac reprogramming

Once damaged, the human heart does a poor job of repairing itself, so this is a key priority for treating heart failure. One way of restoring cardiac function is to reprogram non-cardiac body cells such as fibroblasts into heart muscle cells (cardiomyocytes) using a collection of cardiac transcription factors.

6 Mar 2019

Oxford Genetics successfully negotiates six licensing deals

Mercia Technologies PLC, the national investment group focused on the identification, creation, funding and scaling of innovative technology businesses with high growth potential from the UK regions, today announces that its portfolio company, Oxford Genetics Limited, has successfully negotiated six licensing deals for its scalable gene therapy manufacturing technologies in the last twelve months.

From OXGENE 5 Mar 2019

Scientists create novel tool to advance search for antibacterial drugs

Indiana University researchers are advancing knowledge about how bacteria build their cell walls that could contribute to the search for new antibacterial drugs. They have created a new tool to observe living cells in real time under a microscope.

4 Mar 2019

The Evolution of MDLC in the Pharmaceutical Industry

Dr Kelly Zhang outlines recent advances in multidimensional liquid chromatography (MDLC) for pharmaceutical analysis, to be discussed at Pittcon 2019.

From Pittcon 27 Feb 2019

New test could be a ‘game changer’ in the treatment of chronic lymphocytic leukemia

The first test to quickly and accurately predict how people will respond to standard treatment for the most common type of leukemia has been developed at Cardiff University. The technology could guide doctors’ decisions on which drugs to give to patients.

27 Feb 2019

New cellular atlas could provide a deeper insight into blinding diseases

When it comes to understanding how neurons connect to form circuits in the brain, scientists for decades have turned to the retina of the humble laboratory mouse as an ideal model organism. But as a model for vision and vision-related diseases, mice simply aren't equipped.

22 Feb 2019

Viruses in the intestinal tracts can lead to islet autoimmunity and Type 1 diabetes

Researchers at the Center for Infection and Immunity at the Columbia University Mailman School of Public Health and the University of New South Wales, Sydney, Australia, provide new evidence supporting an association between elevated levels of enteroviruses in the intestinal tracts of children and islet autoimmunity, a precursor to Type 1 diabetes.

20 Feb 2019

Study reveals how helper T cells support memory cells to function optimally

The immune system's killer T cells are crucial in fighting viral infections. A fraction of them, called 'memory cells', live on once infection is controlled in order to fight re-infection by the same virus. They are of great interest as the basis of T cell-based vaccination and immunotherapies.

20 Feb 2019

Unique gene therapy approach paves new way to tackle rare, inherited diseases

Nonsense mutations are single-letter errors in the genetic code that prematurely halt the production of critical proteins. These unfinished proteins are unable to function normally, and nonsense mutations cause 10-15 percent of all inherited genetic diseases, including Duchenne muscular dystrophy, spinal muscular atrophy, cystic fibrosis and polycystic kidney disease.

19 Feb 2019

New AI-driven platform analyze how pathogens infect human cells

Researchers have developed a new AI-driven platform that can analyze how pathogens infect our cells with the precision of a trained biologist.

13 Feb 2019

Inhibiting tuberculosis-induced cell death with immunotherapy

Tuberculosis treatment still entails the intake several antibiotics over a period of many months and is torturous for many patients. The pathogen's increasing multidrug resistance additionally complicates this lengthy treatment, and side effects frequently lead to a discontinuation of treatment and high mortality rates.

12 Feb 2019

New hydrogel-based muscles manipulate and stimulate biological tissue

Human tissues experience a variety of mechanical stimuli that can affect their ability to carry out their physiological functions, such as protecting organs from injury.

11 Feb 2019

Spectrum's ultra-fast digitizer enables breakthrough in cell sorting

Cell sorting plays a fundamental role in molecular biology, pathology, immunology and virology research. It requires the ability to rapidly search through and sort out cells based on their unique chemical features and shapes.

From Spectrum Instrumentation GmbH 6 Feb 2019

New breakthrough study can impact drug development and personalized medicine

A breakthrough for brain tumor drug development and personalized medicine published today in Nature Scientific Reports.

6 Feb 2019

Oxford Nanopore launches new cDNA Kits for its sequencing technology

Oxford Nanopore has launched new '109' cDNA Kits for its real-time, scalable sequencing technology. The new kits provide high throughput whilst generating complete sequences of full-length cDNA strands, with a low input option of just 1ng PolyA+ RNA.

4 Feb 2019

Enhancing HD-MEA Systems with CMOS

At SfN 2018, we spoke to MaxWell Biosystems about their CMOS based HD-MEA systems for recording and stimulating electrogenic cells in-vitro - MaxOne and MaxTwo.

From MaxWell Biosystems 31 Jan 2019

Beckman Coulter Life Sciences announces acquisition of Labcyte

Beckman Coulter Life Sciences today announced its acquisition of Labcyte, a privately held, acoustic liquid handling company based in San Jose, California.

From Beckman Coulter Life Sciences - Automation and Genomics 31 Jan 2019

Researchers call for industry standards to help improve high-throughput genomic sequencing

Researchers from the George Washington University, the U.S. Food and Drug Administration, and industry leaders published in PLOS Biology, describing a standardized communication method for researchers performing high-throughput sequencing called BioCompute.

31 Jan 2019

Synchron and Festo introduce new ultra-high throughput DNA extraction device at SLAS 2019

During SLAS 2019, Synchron and Festo will describe the recent technology breakthrough leading to ultra-high throughput DNA extraction – up to 38,400 extractions per 24 hours.

From Society for Laboratory Automation and Screening (SLAS) 30 Jan 2019

Corning Life Sciences to highlight advanced 3D cell culture technologies and tools at SLAS 2019

Corning Incorporated will showcase advanced 3D cell culture technologies and workflow solutions, and including those for high throughput screening and ADME/toxicology at SLAS 2019.

From Corning Life Sciences 30 Jan 2019