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Study reveals DCAF1 protein's role in colon cancer development through EZH2 phosphorylation

A recent study reveals that DCAF1 is overexpressed and phosphorylates EZH2 in colon cancer cells.

18 Apr 2023

Precise genome editing approach can correct mutation that causes sickle cell disease

Scientists at St. Jude Children’s Research Hospital and the Broad Institute of MIT and Harvard showed how prime editing can correct the mutation that causes sickle cell disease in a potentially curative approach.

18 Apr 2023

Researchers reveal how a new CALM mutation causes deadly arrhythmias

Arrhythmia, when left unchecked, can be life-threatening.

18 Apr 2023

Unravelling the factors influencing host tropism of SARS-CoV-2-related bat coronaviruses

Researchers investigated the tropism of SC2r-CoVs infecting Rhinolophus bats.

18 Apr 2023

A highly efficient platform for detection of SARS-CoV-2 variants

The recent outbreak of the coronavirus disease 2019 (COVID-19) pandemic and the continuous evolution of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) have highlighted the significance of new detection methods for global monitoring and prevention.

17 Apr 2023

How SARS-CoV-2 Omicron subvariants have evolved to evade host T-cell immunity

Researchers investigate whether SARS-CoV-2 and its variants have evolved to evade CD8+ T cell-mediated immunity.

15 Apr 2023

Research reveals molecular features of rare mtDNA mutations

A high-throughput single-cell single-mitochondrial genome sequencing technology known as iMiGseq has provided new insights into mutations of mitochondrial DNA (mtDNA) and offers a platform for assessing mtDNA editing strategies and genetic diagnosis of embryos prior to their implantation.

13 Apr 2023

From Sanger Sequencing to the Human Genome Project: The Evolution of DNA Sequencing Technology

In this inspiring interview, we speak to Dr. Radoje Drmanac, co-founder of Complete Genomics, about the past, present, and future of genomics research.

From MGI 13 Apr 2023

The virological characteristics of XBB.1.16

Researchers perform extensive multiscale investigations to explore virological characteristics of the SARS-CoV-2 Omicron XBB subvariant, XBB.1.16.

12 Apr 2023

Researchers discover important drug target for preventing blood cancer

An international coalition of biomedical researchers co-led by Alexander Bick, MD, PhD, at Vanderbilt University Medical Center has determined a new way to measure the growth rate of precancerous clones of blood stem cells that one day could help doctors lower their patients' risk of blood cancer.

12 Apr 2023

Study provides direct evidence of adaptive evolution in the skin microbiome

Human skin is home to millions of microbes. One of these microbes, Staphylococcus aureus, is an opportunistic pathogen that can invade patches of skin affected by eczema, also known as atopic dermatitis.

12 Apr 2023

New approach identifies significant molecular changes linked to pediatric bipolar disorder

It's extremely difficult to study the biological basis of psychiatric disorders, in part because researchers can't easily collect brain cells from living people to study in the laboratory. Now, University of Utah Health scientists have developed a way around that.

12 Apr 2023

New potential therapeutic developed for diffuse intrinsic pontine glioma using ASO technology

Diffuse intrinsic pontine glioma (DIPG) is a lethal pediatric brain cancer that often kills within a year of diagnosis. Surgery is almost impossible because of the tumors' location.

12 Apr 2023

Optimized genome-editing method opens the door to more effective treatment of genetic diseases

CRISPR-Cas9 is widely used to edit the genome by studying genes of interest and modifying disease-associated genes.

11 Apr 2023

Study highlights the potential long-term neurological effects post-COVID-19

Researchers studied the presence of the SARS-CoV-2 spike protein in the skull-meninges-brain (SMB) axis.

10 Apr 2023

New method estimates mutation risks due to residual radiation from the Fukushima nuclear disaster

Ionizing radiation from nuclear disasters are known to be harmful to the natural environment. The Fukushima Dai-ichi Nuclear Power Plant meltdown that occurred in 2011 is a prominent example of such a disaster in recent memory.

7 Apr 2023

Combinatorial biomarker predicts response to immunotherapy in kidney cancer patients

The number of immune cells in and around kidney tumors, the amount of dead cancer tissue, and mutations to a tumor suppressor gene called PBRM1 form a biomarker signature that can predict — before treatment begins — how well patients with kidney cancer will respond to immunotherapy, according to new research directed by investigators at the Johns Hopkins Kimmel Cancer Center and its Bloomberg~Kimmel Institute for Cancer Immunotherapy.

6 Apr 2023

Study explores the species-specific use of ACE2 receptors by human and animal coronaviruses

Researchers assessed the ability of spike proteins from 24 animal or human coronaviruses to utilize angiotensin-converting enzyme 2.

5 Apr 2023

Promising new combination of drugs identified to treat juvenile myelomonocytic leukemia

Indiana University School of Medicine researchers have identified a promising new combination of drugs to treat juvenile myelomonocytic leukemia (JMML), a rare form of blood cancer that affects children.

5 Apr 2023

Novel molecule may help overcome the devastating symptoms of Duchenne muscular dystrophy

In a new study published in The FASEB Journal, investigators demonstrated the potential of a molecule that may help overcome some of the devastating symptoms of Duchenne muscular dystrophy (DMD), the most common life-limiting congenital neuromuscular disorder.

5 Apr 2023

Mutation News and Research

Study reveals DCAF1 protein's role in colon cancer development through EZH2 phosphorylation

Precise genome editing approach can correct mutation that causes sickle cell disease

Researchers reveal how a new CALM mutation causes deadly arrhythmias

Unravelling the factors influencing host tropism of SARS-CoV-2-related bat coronaviruses

A highly efficient platform for detection of SARS-CoV-2 variants

How SARS-CoV-2 Omicron subvariants have evolved to evade host T-cell immunity

Research reveals molecular features of rare mtDNA mutations

From Sanger Sequencing to the Human Genome Project: The Evolution of DNA Sequencing Technology

The virological characteristics of XBB.1.16

Researchers discover important drug target for preventing blood cancer

Study provides direct evidence of adaptive evolution in the skin microbiome

New approach identifies significant molecular changes linked to pediatric bipolar disorder

New potential therapeutic developed for diffuse intrinsic pontine glioma using ASO technology

Optimized genome-editing method opens the door to more effective treatment of genetic diseases

Study highlights the potential long-term neurological effects post-COVID-19

New method estimates mutation risks due to residual radiation from the Fukushima nuclear disaster

Combinatorial biomarker predicts response to immunotherapy in kidney cancer patients

Study explores the species-specific use of ACE2 receptors by human and animal coronaviruses

Promising new combination of drugs identified to treat juvenile myelomonocytic leukemia

Novel molecule may help overcome the devastating symptoms of Duchenne muscular dystrophy

Industry Focus eBook - Neurology/Neuroscience - 2nd edition eBook

Improving healthcare sustainability through carbon data

A New Approach to Preventing Bladder Cancer Recurrence

Bringing real-time analytics to downstream bioprocess monitoring

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