Pharmaceuticals News and Research

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Opioids like ‘lean’ permeate hip-hop culture, but dangers are downplayed

Nykerrius Williams knows about the close relationship between hip-hop and opioid use. Williams, 27, an independent rapper from Gibsland, Louisiana, who goes by the name Young Nyke, took oxycodone pills for the first time when he was 16 and has continued patterns of misuse of those pills, as well as Lortabs, Xanax and codeine cough syrups, until recently. To him, it's part of the business.

28 May 2021

KHN’s ‘what the health?’: The return of the public option

The "public option" is back — both in Washington, D.C., and the states. President Joe Biden as a candidate supported the idea of a government-run or heavily regulated insurance plan that would compete with private insurance.

28 May 2021

Melatonin prevents kidney damage caused by metabolic complications of obesity

Scientists from the University of Granada (UGR), the Hospital Universitario La Paz (Madrid), and the University of Texas (USA) have taken an important step in the fight against kidney damage and its progression towards kidney failure, which is closely related to diabesity (obesity and its type 2 diabetes) and its complications.

27 May 2021

Reducing COVID-19 burden with monoclonal antibodies and vaccination

Researchers in the United States, the UK and France have shown that using antiviral monoclonal antibodies in combination with vaccination can be expected to suppress the transmission of severe acute respiratory syndrome coronavirus 2 (SARS CoV-2) and reduce the burden of coronavirus disease 2019 (COVID-19) more than vaccination alone.

26 May 2021

Colorado lawmakers wage multifront assault on high drug costs

Tired of waiting for federal action to reduce prescription drug costs, Colorado is acting on its own — even if it must do so with one arm tied behind its back.

25 May 2021

New peptide-like molecules could treat herpes, COVID-19, and the common cold

Among the powerful biochemicals of the human immune system, peptides are one of the best.

24 May 2021

New immunotherapy shows promising results in subgroup of people with type 1 diabetes

A clinical study led by Linköping University and financed by pharmaceuticals company Diamyd Medical has investigated whether immunotherapy against type 1 diabetes can preserve the body's own production of insulin.

24 May 2021

New chemical process uses photocatalytic membrane to remove steroid hormones

Micropollutants such as steroid hormones contaminate drinking water worldwide and pose a significant threat to human health and the environment even in smallest quantities.

22 May 2021

Targeting mTOR pathway can improve the effectiveness of chemotherapies for pediatric brain cancer

Two experimental drug approaches that target vulnerabilities in cancer cell metabolism may extend survival and enhance the effectiveness of standard chemotherapies for a highly aggressive type of pediatric brain cancer.

21 May 2021

Dupilumab considerably reduced asthma exacerbations in young children, shows VOYAGE trial

Results from the VOYAGE study of dupilumab (Dupixent) showed that the monoclonal antibody significantly reduced exacerbations in children ages 6-11 with uncontrolled moderate-to-severe asthma, compared to placebo, according to research presented at the ATS 2021 International Conference. VOYAGE (NCT02948959) is a recently completed randomized, placebo-controlled double-blind multicenter phase 3 clinical trial, that took place in a number of countries.

20 May 2021

Bettersize Announces the Release of Powder Characteristics Guidebook

As powder products become more complex, the need for detailed testing is becoming increasingly urgent. In May 2021, Bettersize raised the bar again with the release of a new guidebook on powder characteristics.

From Bettersize Instruments 20 May 2021

Combination approach can improve the success rate of cancer treatment

A new cancer vaccine could boost the positive effects of existing immunotherapy drugs, improving the success rate of treatments from 20% to 75% of cases, according to a new study by immunologists from the University of Konstanz.

19 May 2021

Sotagliflozin reduces adverse cardiovascular events across patients with diabetes, heart failure

Patients with both diabetes and heart failure who were treated with sotagliflozin, a novel investigational drug for diabetes, for a median of nine to 16 months experienced reductions of 22% to 43% in the risk of death or worsening heart failure compared with similar patients who were treated with a placebo

18 May 2021

Investigational drug reduced triglycerides in patients with severe hypertriglyceridemia, acute pancreatitis

The investigational drug evinacumab reduced triglycerides in patients with severe hypertriglyceridemia (sHTG) and a history of hospitalizations for acute pancreatitis in a phase 2 global study led by Mount Sinai.

17 May 2021

Sacubitril/valsartan drug did not significantly reduce cardiovascular death after heart attack

The heart failure drug sacubitril/valsartan did not significantly reduce the rate of heart failure or cardiovascular death following a heart attack compared to ramipril, an angiotensin-converting enzyme (ACE) inhibitor proven effective in improving survival following heart attacks.

17 May 2021

Phase 2 trial shows INO-4800 SARS-CoV-2 DNA vaccine safe and tolerable in adults

Preliminary clinical trial results from an ongoing Phase 2/3 trial led by Laurent M. Humeau of Inovio Pharmaceuticals suggest the two-dose INO-4800 vaccine is safe for use in adults of varying ages. The results expand on phase 1 trial results that found the vaccine was safe and tolerable in 38 participants.

16 May 2021

Immunity developed by SARS-CoV-2 infection can protect against E484K variants, suggests study

A team of scientists from Japan has recently investigated the neutralizing potency of convalescent sera against currently circulating SARS-CoV-2 variants with multiple spike mutations.

13 May 2021

New peptide could allow cannabis to fight pain without side effects

Many people live with chronic pain, and in some cases, cannabis can provide relief. But the drug also can significantly impact memory and other cognitive functions.

12 May 2021

New publication details strengths and weaknesses of the U.S. health insurance system

A landmark work that details the strengths and weaknesses of the U.S. health insurance system, including how it lags behind those of other wealthy countries in measures that include mortality from both preventable and treatable causes, has been published.

12 May 2021

Don’t eat the yellowstone snow: Elite ski resort aims to turn sewage into powder

An exclusive Montana resort wants to turn sewage into snow so that its rich and famous members can ski its slopes in a winter season that's shrinking because of climate change.

12 May 2021

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Pharmaceuticals News and Research

Opioids like ‘lean’ permeate hip-hop culture, but dangers are downplayed

KHN’s ‘what the health?’: The return of the public option

Melatonin prevents kidney damage caused by metabolic complications of obesity

Reducing COVID-19 burden with monoclonal antibodies and vaccination

Colorado lawmakers wage multifront assault on high drug costs

New peptide-like molecules could treat herpes, COVID-19, and the common cold

New immunotherapy shows promising results in subgroup of people with type 1 diabetes

New chemical process uses photocatalytic membrane to remove steroid hormones

Targeting mTOR pathway can improve the effectiveness of chemotherapies for pediatric brain cancer

Dupilumab considerably reduced asthma exacerbations in young children, shows VOYAGE trial

Bettersize Announces the Release of Powder Characteristics Guidebook

Combination approach can improve the success rate of cancer treatment

Sotagliflozin reduces adverse cardiovascular events across patients with diabetes, heart failure

Investigational drug reduced triglycerides in patients with severe hypertriglyceridemia, acute pancreatitis

Sacubitril/valsartan drug did not significantly reduce cardiovascular death after heart attack

Phase 2 trial shows INO-4800 SARS-CoV-2 DNA vaccine safe and tolerable in adults

Immunity developed by SARS-CoV-2 infection can protect against E484K variants, suggests study

New peptide could allow cannabis to fight pain without side effects

New publication details strengths and weaknesses of the U.S. health insurance system

Don’t eat the yellowstone snow: Elite ski resort aims to turn sewage into powder

Ultimate guide to the essential tools for the characterization of proteins, polymers and nanoparticles eBook

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