Polymerase News and Research

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2022 monkeypox presents with new symptoms

In a recent study published in The Lancet Infectious Diseases, researchers described the clinical and demographical characteristics of monkeypox virus infections among individuals attending sexual health centers in the United Kingdom (UK).

6 Jul 2022

The contamination of surfaces in hospital rooms housing monkeypox patients

Researchers investigated the contamination of surfaces in hospital rooms housing monkeypox patients.

6 Jul 2022

Intrahost genetic diversity and evolution of the SARS-CoV-2 B.1.517 lineage during chronic infection of an immunocompromised individual

Researchers investigated the intrahost evolution and genetic diversity of the SARS-CoV-2 B.1.517 variant in an immunosuppressed person with chronic COVID-19.

6 Jul 2022

Paxlovid resistance associated with SARS-CoV-2 3CLpro mutations

In a recent study published in the bioRxiv* preprint server, researchers at the Medical University of Innsbruck assessed the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) 3CLpro mutations responsible for Paxlovid resistance. The 3-chymotrypsin-like protease (3CLPro), or main protease (Mpro), is the main protease found in coronaviruses.

6 Jul 2022

Acute scrotal infections among COVID-19 patients significantly associated with disease severity in new study

In a new study, researchers assessed the influence of severe coronavirus disease 2019 on scrotal infections.

5 Jul 2022

Deep RNA sequencing with molecular dynamic simulations can detect neutralizing antibodies elicited by COVID-19 patients

In a new study, researchers reported on the non-ACE2 blocking neutralizing antibodies elicited in response to severe coronavirus disease 2019 using deep ribonucleic acid sequencing with >100 million reads per sample and molecular dynamic simulations.

5 Jul 2022

Effectiveness of two and three doses of BNT162b2 against hospital and ED admissions for BA.1 and BA.2 infection

Researchers compared the effectiveness of two and three-dose regimens of COVID-19 vaccine BNT1262b against Omicron BA.1 and BA.2-related hospital and ED admissions.

5 Jul 2022

The varying patterns of acute respiratory infection hospitalizations before and during two pandemic years

Investigators analyzed the varying pattern of respiratory viruses resulting in hospitalizations from 2012-2013 to 2021-2022 in Canada.

5 Jul 2022

Study looks at pneumococcal carriage among over 60's during COVID pandemic

In a recent article posted to the medRxiv* preprint server, researchers in the United States analyzed the pneumococcal carriage in older adults in the Greater New Haven Area, United States (US), during the implementation of coronavirus disease 2019 (COVID-19) mitigation strategies.

4 Jul 2022

Enteric viruses found to transmit through the salivary route

Researchers reported on the productive and persistent infection of salivary glands (SGs) by enteric viruses, with oral cavity titers similar to intestinal titers.

4 Jul 2022

Researchers investigate prevention and therapy against monkeypox infection

Researchers reviewed the preventive and therapeutic measures against monkeypox.

4 Jul 2022

Exploring flavonols in the inhibition of SARS-CoV-2 replication

Researchers assessed the efficiency of flavonols in SARS-CoV-2 inhibition.

4 Jul 2022

Lower diaphragmatic thickness found among long COVID patients with unspecific fatigue and dyspnea

Researchers defined the sonographic diaphragm phenotype of long coronavirus disease (COVID) patients with unspecific fatigue and dyspnea.

4 Jul 2022

Remdesivir resistance in renal transplant patients with long COVID-19

A new study has reported two renal transplant cases, in which individuals, after being exposed to remdesivir, developed a resistance to the drug.

1 Jul 2022

Study evaluates if adults with obesity and a history of SARS-CoV-2 infection demonstrate poorer T cell immunity

Researchers assessed the association between obesity and T cell frequencies specific to the SARS-CoV-2 antigen.

1 Jul 2022

The identification and characterization of a thermophilic Cas13a ortholog highly active at the temperatures required for RT-LAMP

Researchers developed a new detection assay for SARS-CoV-2.

1 Jul 2022

BNT162b2 vaccine induces moderate SARS-CoV-2 immunity in children 5 to 11

In a recent study published in the New England Journal of Medicine, researchers evaluated the effectiveness of the BNT162b2 vaccine against the new severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variant of concern (VOC) Omicron in five to 11-year-old children.

30 Jun 2022

Polymerase News and Research

2022 monkeypox presents with new symptoms

The contamination of surfaces in hospital rooms housing monkeypox patients

Intrahost genetic diversity and evolution of the SARS-CoV-2 B.1.517 lineage during chronic infection of an immunocompromised individual

Paxlovid resistance associated with SARS-CoV-2 3CLpro mutations

Acute scrotal infections among COVID-19 patients significantly associated with disease severity in new study

Deep RNA sequencing with molecular dynamic simulations can detect neutralizing antibodies elicited by COVID-19 patients

Effectiveness of two and three doses of BNT162b2 against hospital and ED admissions for BA.1 and BA.2 infection

The varying patterns of acute respiratory infection hospitalizations before and during two pandemic years

Study looks at pneumococcal carriage among over 60's during COVID pandemic

Enteric viruses found to transmit through the salivary route

Researchers investigate prevention and therapy against monkeypox infection

Exploring flavonols in the inhibition of SARS-CoV-2 replication

Lower diaphragmatic thickness found among long COVID patients with unspecific fatigue and dyspnea

Remdesivir resistance in renal transplant patients with long COVID-19

Study evaluates if adults with obesity and a history of SARS-CoV-2 infection demonstrate poorer T cell immunity

The identification and characterization of a thermophilic Cas13a ortholog highly active at the temperatures required for RT-LAMP

BNT162b2 vaccine induces moderate SARS-CoV-2 immunity in children 5 to 11

Rapid test can identify which variant has infected a COVID-19 patient in just a few hours

A fast, highly sensitive, point-of-care RT-LAMP and CRISPR/Cas12a assay for the detection of SARS-CoV-2

South African study shows COVID severity of Omicron BA.1, BA.4, BA.5 all similar

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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