Antibody News and Research

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An antibody is a blood protein that is produced in response to and counteracts an antigen. Antibodies are produced in response to disease and help the body fight against the particular disease. In this way, antibodies help the body develop an immunity to disease.

Australia attempts to develop treatments against Hendra virus and Nipah virus

With funding from the United States' National Institutes of Health (NIH), and in collaboration with a research team led by Dr Christopher Broder at the Uniformed Services University of the Health Sciences in Bethesda Maryland, CSIRO Livestock Industries' Australian Animal Health Laboratory (AAHL) in Geelong is attempting to develop treatments against Hendra virus and Nipah virus.

9 Jan 2005

Core promoter mutants of Hepatitis B Virus e Antigen associated with development of fulminant hepatitis and liver cancer

Scientists in Brown Medical School, Providence, USA, have found that core promoter mutants of Hepatitis B Virus e Antigen replicate at up to 10-fold higher levels in transfected human hepatoma cells than the wild-type virus.

9 Jan 2005

Processes shed light on how DNA recombination mechanisms are related

Peter W. Atkinson, a University of California, Riverside professor of entomology and member of the university’s Institute for Integrative Genome Biology, is part of a team that has linked the movement of small pieces of DNA, known as transposable elements, to a process called V(D)J recombination that produces the genetic diversity responsible for the production of antibodies.

6 Jan 2005

New technique could lead to more effective therapies for AIDS

When researchers came up with the powerful cocktail of anti-HIV drugs known as highly active antiretroviral therapy (HAART), they hoped they had found a way to finally rid the body of the virus. But they were wrong.

4 Jan 2005

Bio-Rad receives FDA approval for new HIV rapid test

Bio-Rad Laboratories announced today that it recently received approval from the U.S. Food and Drug Administration (FDA) for its new Multispot HIV-1/HIV-2 Rapid Test.

4 Jan 2005

High levels of a blood protein called mannose-binding lectin associated with lower risk of heart attack

High levels of a blood protein called mannose-binding lectin (MBL) are associated with lower risk of heart attack, particularly among diabetics, report Saevardottir and colleagues.

28 Dec 2004

New technique for tracking gene regulators

Finding out where gene-regulator proteins bind to DNA and identifying the genes they regulate just got a step easier thanks to a new technique developed by scientists at the U.S. Department of Energy’s Brookhaven National Laboratory.

28 Dec 2004

Course of injections in childhood might help protect people from heart disease later in life

A course of injections in childhood might help protect people from heart disease later in life. And for those whose arteries are already clogged up, a dose of antibodies could provide immediate benefits. That's the enticing vision raised by animal studies.

26 Dec 2004

Shape of a protein on the surface of pneumonia bacteria helps germs invade the human bloodstream

Scientists at St. Jude Children's Research Hospital have discovered that the shape of a protein on the surface of pneumonia bacteria helps these germs invade the human bloodstream.

23 Dec 2004

Somatic hypermutation (SHM) should prove to be extremely useful in directed protein evolution

Fascinated by the efficient way the human immune system generates a rapid response to create a near-infinite variety of antibodies, researchers have "hijacked" that machinery and used it to evolve a new type of fluorescent protein.

23 Dec 2004

Researchers can now inexpensively program the chemical synthesis of entire genes on a single microchip

Devices the size of a pager now have greater capabilities than computers that once occupied an entire room. Similar advances are being made in the emerging field of synthetic biology at the University of Houston, now allowing researchers to inexpensively program the chemical synthesis of entire genes on a single microchip.

23 Dec 2004

Fluorescent colors used to separate cells visually

The latest holiday gifts being offered to the scientific community this season by scientists in the laboratory of Howard Hughes Medical Institute investigator Roger Y. Tsien come in a dazzling variety of hues -- cherry, strawberry, tangerine, tomato, orange, banana and honeydew. The color spectrum would make Pantone proud.

22 Dec 2004

Jumping genes help explain immune system's remarkable ability

A team led by Johns Hopkins scientists has found the first clear evidence that the process behind the human immune system's remarkable ability to recognize and respond to a million different proteins might have originated from a family of genes whose only apparent function is to jump around in genetic material.

22 Dec 2004

GlaxoSmithKline acquires full marketing and development rights for BEXXAR worldwide

GlaxoSmithKline announced that it has reached an agreement with Corixa Corporation to acquire worldwide rights and responsibilities related to the manufacturing, development and commercialization of the BEXXAR® therapeutic regimen.

14 Dec 2004

Vaccinating mice against Lyme disease could help reduce the risk of transmission of the disease to humans

Vaccinating large populations of white-footed mice against the bacterium that causes Lyme disease could help reduce the risk of transmission of the disease to humans, says a study supported by the National Institute of Allergy and Infectious Diseases (NIAID).

14 Dec 2004

Start today of human tests for a preventive vaccine against the respiratory disease SARS

Powerful research tools that speed up vaccine development have led to the start today of human tests for a preventive vaccine against the respiratory disease SARS. The disease killed hundreds of people around the world before it was brought under control in 2003 with aggressive conventional public health measures.

13 Dec 2004

Patent issued for generating genetically evolved mammalian cells through the regulation of mismatch repair

Morphotek announced today the issuance of United States Patent 6,825,038 covering the regulation of mismatch repair (MMR), a powerful process for generating functional diversity in mammalian cells, to yield sibs exhibiting desirable phenotypes for target discovery, drug screening and/or product development.

13 Dec 2004

FDA accepts Genmab's Investigational New Drug Application for active rheumatoid arthritis treatment

Genmab announced today the US Food and Drug Administration (FDA) accepted its Investigational New Drug Application (IND) to start a Phase I/II dose escalation trial for HuMax-CD20 to treat patients with active rheumatoid arthritis (RA) who have failed one treatment with one or more disease modifying anti-rheumatic drugs (DMARDs).

13 Dec 2004

Targeted screening of high-risk groups for genital herpes may prevent disease transmission

Identifying asymptomatic people with genital herpes infection through targeted screening of high-risk groups may prevent disease transmission. However, widespread screening of pregnant women is unlikely to reduce the occurrence of herpes in newborns, according to an article in the January 1 issue of Clinical Infectious Diseases, now available online.

13 Dec 2004

Understanding what causes narcolepsy

Results of a preliminary study in this week’s issue of THE LANCET suggest a step forward in our understanding of the processes behind narcolepsy; there appears to be an underlying autoimmune process for people with a certain genetic profile. Future diagnostic testing of people with this profile should lead to substantial improvements in disease treatment.

13 Dec 2004

Antibody News and Research

Further Reading

Australia attempts to develop treatments against Hendra virus and Nipah virus

Core promoter mutants of Hepatitis B Virus e Antigen associated with development of fulminant hepatitis and liver cancer

Processes shed light on how DNA recombination mechanisms are related

New technique could lead to more effective therapies for AIDS

Bio-Rad receives FDA approval for new HIV rapid test

High levels of a blood protein called mannose-binding lectin associated with lower risk of heart attack

New technique for tracking gene regulators

Course of injections in childhood might help protect people from heart disease later in life

Shape of a protein on the surface of pneumonia bacteria helps germs invade the human bloodstream

Somatic hypermutation (SHM) should prove to be extremely useful in directed protein evolution

Researchers can now inexpensively program the chemical synthesis of entire genes on a single microchip

Fluorescent colors used to separate cells visually

Jumping genes help explain immune system's remarkable ability

GlaxoSmithKline acquires full marketing and development rights for BEXXAR worldwide

Vaccinating mice against Lyme disease could help reduce the risk of transmission of the disease to humans

Start today of human tests for a preventive vaccine against the respiratory disease SARS

Patent issued for generating genetically evolved mammalian cells through the regulation of mismatch repair

FDA accepts Genmab's Investigational New Drug Application for active rheumatoid arthritis treatment

Targeted screening of high-risk groups for genital herpes may prevent disease transmission

Understanding what causes narcolepsy

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