Antibody News and Research

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An antibody is a blood protein that is produced in response to and counteracts an antigen. Antibodies are produced in response to disease and help the body fight against the particular disease. In this way, antibodies help the body develop an immunity to disease.

Potential vaccine for the deadly toxin ricin

A potential vaccine for the deadly toxin ricin, a "Category B" biological agent, will enter the first phase of clinical testing in coming weeks at UT Southwestern Medical Center at Dallas.

30 Nov 2004

Key molecule helps identify renal cell carcinoma

Mayo Clinic researchers have discovered a key molecule that lets doctors identify one of the most aggressive types of kidney cancer. Patients with renal cell carcinoma who have higher levels of a molecule known as B7-H1 in their tumors are nearly five times more likely to die from the disease than patients with low levels or an absence of the molecule.

30 Nov 2004

Avastin plus Folfox4 chemotherapy significantly extends survival in second-line metastatic colorectal cancer

Genentech and Roche today announced that a randomized Phase III study of Avastin™ (bevacizumab) plus the FOLFOX4 chemotherapy regimen (oxaliplatin/5-FU/leucovorin), compared to FOLFOX4 alone, in second-line metastatic colorectal cancer patients achieved its primary endpoint of improving overall survival.

29 Nov 2004

MedImmune and Medarex have announced a collaboration to develop antibodies

MedImmune and Medarex have announced a collaboration to develop antibodies targeting interferon-alpha and the type I interferon receptor 1.

24 Nov 2004

FDA approval of Tysabri, for the treatment of multiple sclerosis

Biogen and Elan Corporation have announced that the U.S. Food and Drug Administration (FDA) has approved Tysabri (natalizumab), as treatment for relapsing forms of multiple sclerosis (MS) to reduce the frequency of clinical relapses.

24 Nov 2004

New research may lead to new treatments for spinal cord injury and multiple sclerosis

For the first time, researchers have used human embryonic stem cells to create new insulating tissue for nerve fibers in a live animal model – a finding that has potentially important implications for treatment of spinal cord injury and multiple sclerosis.

23 Nov 2004

Vaccinex and Biocon to co-develop at least four therapeutic antibody products

The collaboration combines Vaccinex's unique capabilities to discover fully human monoclonal antibodies using its proprietary antibody discovery technology and Biocon's proven expertise in clinical research and biologics manufacturing.

19 Nov 2004

Family experience guides Alzheimer’s research

After watching his father struggle with and ultimately succumb to Alzheimer’s disease, ASU professor Michael Sierks shifted his research focus from starch hydrolyzing to neurodegenerative diseases.

18 Nov 2004

Evidence of exposure to a monkey virus possibly related to cancer has been found in the blood of North American zoo workers

The virus, a polyomavirus known as simian virus 40 (SV40), has long been a subject of public health concern, in part because it has been shown to cause cancer in laboratory animals, and some investigators have reported SV40 DNA in human tumors.

18 Nov 2004

Safe, effective and reversible alternative contraceptives for men

Most men know when their family is complete, and vasectomy remains the most effective and safest form of sterilization. Around 10% of vasectomized men in the U.S desire vasectomy reversal due to the high divorce rate in this country and other life circumstances.

16 Nov 2004

Five advanced tests provide answers to couples with unexplained infertility

For couples struggling with infertility, "all routine tests came back negative" are not the words they want to hear. With up to 15% of couples with "unexplained infertility" and another 3% struggling with recurrent pregnancy loss, advanced tests help doctors find answers for their most challenging cases.

16 Nov 2004

Research opens up new avenues to diagnosis and treat Lyme disease

Researchers at Yale School of Medicine have identified a Lyme disease receptor called TROSPA that is used by disease agents to invade ticks.

14 Nov 2004

Vaccine provides new hope to the millions of people who suffer from food allergies

A team led by a researcher at the Stanford University School of Medicine has developed vaccines that vastly reduce or eliminate dogs' allergic reactions to three major food allergens: peanuts, milk and wheat. The vaccines' benefits lasted at least three months.

14 Nov 2004

Hep C and HIV among injecting drug users in London are higher than expected

Levels of hepatitis C virus and HIV among injecting drug users in London are higher than expected, according to a study published online by the BMJ.

14 Nov 2004

Kids who outgrow peanut allergy need to eat peanut products at least once a month in order to maintain tolerance

Kids who outgrow peanut allergy have a slight chance of recurrence, but researchers from the Johns Hopkins Children's Center report that the risk is much lower in children who frequently eat peanuts or peanut products.

11 Nov 2004

Abbott's investigational anti-interleukin-12 fully human monoclonal antibody in Crohn's disease study

Results of a Phase II study of Abbott's ABT-874, a fully human anti-interleukin-12 (IL-12) monoclonal antibody, will appear tomorrow in the New England Journal of Medicine citing treatment with ABT-874 shows differences in response and remission in patients with active Crohn's disease compared to placebo, in one arm of the study.

10 Nov 2004

New studies demonstrate efficacy of novel Lipoxin analog in laboratory models of Crohn's disease

Berlex announced today that new laboratory results demonstrate that its modified version of the naturally occurring lipoxin molecule exerts potent anti-inflammatory and immunomodulatory effects in Crohn's disease in vivo models and may provide a promising new oral treatment.

9 Nov 2004

Antibody News and Research

Further Reading

Potential vaccine for the deadly toxin ricin

Key molecule helps identify renal cell carcinoma

Avastin plus Folfox4 chemotherapy significantly extends survival in second-line metastatic colorectal cancer

MedImmune and Medarex have announced a collaboration to develop antibodies

FDA approval of Tysabri, for the treatment of multiple sclerosis

New research may lead to new treatments for spinal cord injury and multiple sclerosis

Vaccinex and Biocon to co-develop at least four therapeutic antibody products

Family experience guides Alzheimer’s research

Evidence of exposure to a monkey virus possibly related to cancer has been found in the blood of North American zoo workers

Safe, effective and reversible alternative contraceptives for men

Five advanced tests provide answers to couples with unexplained infertility

Research opens up new avenues to diagnosis and treat Lyme disease

Vaccine provides new hope to the millions of people who suffer from food allergies

Hep C and HIV among injecting drug users in London are higher than expected

Kids who outgrow peanut allergy need to eat peanut products at least once a month in order to maintain tolerance

Abbott's investigational anti-interleukin-12 fully human monoclonal antibody in Crohn's disease study

New studies demonstrate efficacy of novel Lipoxin analog in laboratory models of Crohn's disease

U.S. Patent for generating genetically altered antibody producing cell lines

Testosterone may impede immunity

Tiny, vibrating paddle oscillator senses the mass of a virus

Accelerating therapeutic antibody discovery and development eBook

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Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

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