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Hospital sinks fuel antibiotic-resistant bacteria spread

A new study published today in the American Journal of Infection Control reports the infection prevention steps taken to control a months-long multispecies outbreak of carbapenemase-producing Enterobacterales that occurred in a pediatric ward at the Toho University Omori Medical Center in Tokyo in 2017.

12 Apr 2024

Study reveals how DNA gyrase resolves DNA entanglements

Picture in your mind a traditional "landline" telephone with a coiled cord connecting the handset to the phone.

12 Apr 2024

Blocking polyphosphates could help treat chronic infections

Most disease-causing bacteria are known for their speed: In mere minutes, they can double their population, quickly making a person sick.

12 Apr 2024

Rising antibiotic resistance prompts shift to ecological research strategies in infection control

The need to enhance research on the interactions between bacterial pathogens and commensals within human microbiomes.

12 Apr 2024

Study reveals key gut microbiome differences in prediabetic patients

Study explores the differences in gut microbiome composition between prediabetic patients and healthy individuals, revealing significant variations that correlate with altered metabolic functions and potential diabetes progression.

11 Apr 2024

Researchers call for a revamped fungal priority list to combat regional disease burdens

Study critiques the World Health Organization's fungal priority pathogens list for not fully reflecting the global burden of fungal diseases, advocating for a revised list that considers regional disparities and elevates the priority of pathogens like Mucorales and Histoplasma spp. to better align with their impact on public health.

11 Apr 2024

Tumor microbiomes offer new insights for enhancing cancer therapies

Comprehensive review reveals the significant impact of tumor-resident bacteria on metastatic cancer, showing how microbiome genomes influence tumor biology, immune system response, and treatment effectiveness. It lays the groundwork for utilizing bacteria-focused therapies to complement traditional cancer treatments.

11 Apr 2024

Rethinking the germ theory: A balanced take on microbes and disease outcomes

Review explores the complexities of infectious disease outcomes through a balanced perspective, emphasizing the interplay between pathogenic microbes and host conditions, challenging the traditional germ-disease theory by proposing a more integrated view that considers both pathogen virulence and host immunity's impact on disease manifestation.

10 Apr 2024

New generative AI tool models the infant microbiome

The gut microbiome has a profound impact on the health and development of infants. Research shows that dysbiosis - or imbalances in the microbial community - is associated with gastrointestinal diseases and neurodevelopmental deficits.

10 Apr 2024

Unraveling the complex web of rectal infections and the microbiome in MSM

Study delves into the relationships between various sexually transmitted infections, including Neisseria gonorrhoeae, Chlamydia trachomatis, Torquetenovirus, and high-risk HPV, and their effects on the anorectal microbiome among men who have sex with men (MSM), unveiling complex interactions that may influence infection outcomes and treatment strategies.

10 Apr 2024

Researchers compile a comprehensive catalog of bacteria living in cancer metastases

Researchers at the Netherlands Cancer Institute have compiled a detailed catalog of bacteria living in cancer metastases.

9 Apr 2024

Denmark's pertussis epidemic reveals the power of maternal vaccination

A study published in Eurosurveillance details the 2023 pertussis epidemic in Denmark, emphasizing the age-specific incidence, the role of maternal vaccination in reducing infant hospitalizations, and the impact of vaccination strategies on managing the outbreak.

8 Apr 2024

Gut-friendly psychobiotics could brighten moods and fight depression

Review uncovers that psychobiotics may offer supportive treatment for depression by restoring gut microbiome balance and positively influencing the microbiome-gut-brain axis, which is crucial for mental health and well-being.

8 Apr 2024

Wound warriors: How microbes influence healing and infection risks

Study explores how wound microbiota affect skin repair and infection risk by altering host immune responses, underscoring the complexity of microbial interactions in wound healing.

7 Apr 2024

Oral spray-based vaccine is a potential alternative to antibiotic treatments for recurrent UTIs

Recurrent Urinary Tract Infections (UTIs) can be prevented for up to nine years in more than half of people given an oral spray-based vaccine and is a potential alternative to antibiotic treatments, finds research.

7 Apr 2024

Blast exposure can cause intestinal permeability, study shows

A study by New York and Rocky Mountain U.S. Department of Veterans Affairs researchers showed blast exposure can cause intestinal permeability, a condition that can lead to gut bacteria entering the bloodstream and causing problems in other parts of the body.

5 Apr 2024