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Newly identified pathway transforms biologically inert peptide into structurally complex antibiotics

Researchers in the Princeton University Department of Chemistry have discovered a new multi-step pathway through which bacteria found in the mammalian gut produce antimicrobial peptides.

14 Nov 2022

Harnessing the natural potential of venom for drug discovery

Steven Trim, Founder and Cheif Scientific Officer at Venomtech, tells NewsMedical how UK-based Venomtech® harnesses the power of naturally-produced venoms obtained from a collection of nearly 200 species of spiders, scorpions, and centipedes to create compound libraries for drug discovery.

From INTEGRA Biosciences 14 Nov 2022

Cancer Research Horizons: The Innovation Engine of Cancer Research UK

Following ELRIG 2022, News-Medical speaks with Cancer Research Horizons, the innovation engine of Cancer Research UK about their efforts to advance the drug discovery sector.

From Cancer Research UK 14 Nov 2022

Mercury exposure during pregnancy could boost growth rates of fetus and infant

In a new study, researchers used a physiologically-based pharmacokinetic (PBPK) model to calculate the predicted concentration of MeHg in a given organ with time.

10 Nov 2022

Expanding the therapeutic toolbox for mood disorders with psychoactive drugs

There is a need for new, effective treatments for mental illnesses like depression and anxiety. Researchers are expanding the field's therapeutic toolbox by investigating the antidepressant and anxiolytic properties of drugs such as psilocybin and cannabis.

9 Nov 2022

Researchers find an innovative approach to improve waste clearance from the brain

Alzheimer's, Parkinson's and many other neurodegenerative diseases are marked by damaging clusters of proteins in the brain. Scientists have expended enormous effort searching for ways to treat such conditions by clearing these toxic clusters but have had limited success.

9 Nov 2022

Does fenofibrate improve clinical outcomes in patients with COVID-19?

Researchers assessed the effect of fenofibrate on acute COVID-19.

9 Nov 2022

The direct and indirect effects of COVID-19 on people with type 1 and type 2 diabetes

A recent study published in The Lancet Diabetes & Endocrinology discussed the impact of COVID-19 on individuals with diabetes.

9 Nov 2022

Study identifies novel inhibitors against SARS-CoV-2 main protease

In a recent study posted to the bioRxiv* server, researchers at the University of Arizona screened ~11 million severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) main protease (MPro)-inhibiting small compounds in the ZINC15 database using a structure-based in-silico screening method.

8 Nov 2022

New breakthrough could help spot lung cancer earlier and improve patient outcomes

Scientists investigating the mechanics of the early stages of lung cancer have identified a new potential treatment, which could also aid early detection of the disease.

8 Nov 2022

Green tea catechins and resveratrol display neuroprotective properties in Alzheimer's models

In a recent study published in the journal Free Radical Biology and Medicine, researchers screened for neuroprotective compounds against Alzheimer’s disease (AD).

3 Nov 2022

Accelerating Scientific Discoveries through Advanced Data Analysis Platforms

In this interview, we speak to Victor Wong, Chief Scientific Officer at Core Life Analytics, about their StratoMineRTM product and how it helps researchers to rapidly process their data.

From Core Life Analytics 3 Nov 2022

Researchers provide insights on how to overcome resistance in cancer therapy

The latest developmental drugs, particularly for the use in oncology, rely on the targeted degradation of harmful pathogenic proteins.

3 Nov 2022

The acute and chronic impact of pod-based e-cigarettes on vascular health

Researchers evaluated the impact of PEC [pod-based electronic (e)-cigarette] usage on cardiovascular (CVS) health under the agenesis of the AHA’s TCORS (tobacco center for regulatory science) group.

2 Nov 2022

Is maternal caffeine consumption associated with child growth, and are such associations present in low-consumption groups?

A new paper published in JAMA Network Open discusses the relationship between caffeine consumption in pregnancy and the future growth of the offspring.

1 Nov 2022

Ubiquigent obtains exclusive license for UbiSite technology to strengthen its specialist drug discovery services

Ubiquigent Limited (Ubiquigent), a drug discovery and development company harnessing novel deubiquitylase (DUB) modulators as new therapeutics for areas of high unmet medical need, has signed an exclusive license with the University of Southern Denmark for its UbiSite® technology.

31 Oct 2022

Compound News and Research

Newly identified pathway transforms biologically inert peptide into structurally complex antibiotics

Harnessing the natural potential of venom for drug discovery

Cancer Research Horizons: The Innovation Engine of Cancer Research UK

Mercury exposure during pregnancy could boost growth rates of fetus and infant

Expanding the therapeutic toolbox for mood disorders with psychoactive drugs

Researchers find an innovative approach to improve waste clearance from the brain

Does fenofibrate improve clinical outcomes in patients with COVID-19?

The direct and indirect effects of COVID-19 on people with type 1 and type 2 diabetes

Study identifies novel inhibitors against SARS-CoV-2 main protease

New breakthrough could help spot lung cancer earlier and improve patient outcomes

Green tea catechins and resveratrol display neuroprotective properties in Alzheimer's models

Accelerating Scientific Discoveries through Advanced Data Analysis Platforms

Researchers provide insights on how to overcome resistance in cancer therapy

The acute and chronic impact of pod-based e-cigarettes on vascular health

Is maternal caffeine consumption associated with child growth, and are such associations present in low-consumption groups?

Ubiquigent obtains exclusive license for UbiSite technology to strengthen its specialist drug discovery services

Piceatannol and mTOR inhibitor combination proves be an attractive therapeutic strategy for gastric cancer

Researchers propose origin-of-life molecule as therapeutic target for tailored cancer therapies

Huntington's disease impairs autophagy in older patients

Researchers discover how hydroquinine inhibits major drug-resistant bacteria

Advancing therapeutic biopolymer development eBook

Improving healthcare sustainability through carbon data

A New Approach to Preventing Bladder Cancer Recurrence

Bringing real-time analytics to downstream bioprocess monitoring

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