Microscopy News and Research

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Potent antibody with a novel neutralization mechanism against SARS-CoV-2 variants

In a recent study posted to the bioRxiv* pre-print server, researchers in the United States described a severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)-neutralizing monoclonal antibody (mAb) SP1-77 that broadly neutralized its multiple variants of concern (VOCs).

28 Jun 2022

Shapeshifting behavior of E. coli may offer clues to combat urinary tract infections

Urinary tract infections are both very common and potentially very dangerous. More than half of all Australian women will suffer from a UTI in their lifetime, and nearly one in three women will have an infection requiring treatment with antibiotics before the age of 24.

28 Jun 2022

Cell-based assay highlights differences in antibody neutralizing capacity for SARS-CoV-2 variants

A recent study by scientists at Celentyx Ltd, the University of Birmingham, and the University of Warwick and posted to the bioRxiv* preprint server illustrated a cell-based severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike (S) protein attachment assay.

28 Jun 2022

Recombinant SARS-CoV-2 harboring double reporters for COVID-19 surveillance

In a recent article posted to the bioRxiv* preprint server, researchers at Texas Biomedical Research Institute, Georgia State University, and the University of Alabama at Birmingham developed a bireporter-expressing recombinant severe acute respiratory syndrome coronavirus 2 (rSARS-CoV-2) for tracking SARS-CoV-2 infection.

27 Jun 2022

A full model of the SARS-CoV-2 spike protein for studying its atomic-level dynamics by multiple microsecond simulations

Researchers constructed a full-length SARS-CoV-2 spike structure in its membrane-bound state to study functionally relevant aspects of its global conformational dynamics.

27 Jun 2022

Three-dimensional microscope data reveals an expanded network of interneurons in the human brain

The analysis of the human brain is a central goal of neuroscience. However, for methodological reasons, research has largely focused on model organisms, in particular the mouse.

23 Jun 2022

Fragment crystallizable-altered COVID-19 antibodies efficacious across two animal models

A recent article posted to the bioRxiv* preprint server identified numerous efficacious severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) antibodies from convalescent SARS-CoV-2 patients.

23 Jun 2022

Study unveils a precise model for the stinging organelle of starlet sea anemone

Summertime beachgoers are all too familiar with the painful reality of a jellyfish sting. But how do the stinging cells of jellyfish and their coral and sea anemone cousins actually work? New research from the Stowers Institute for Medical Research unveils a precise operational model for the stinging organelle of the starlet sea anemone, Nematostella vectensis.

23 Jun 2022

Researchers measure temperature-dependent photovoltaic external quantum efficiency to transform the future of solar cells

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From Linkam Scientific Instruments 23 Jun 2022

The possible immune-mediated mechanisms causing CNS alterations during and post-acute SARS-CoV-2 infection

In a recent review published in Immunity, researchers explored potential mechanisms of neuro-immune pathophysiology of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections.

22 Jun 2022

Genetic discovery may pave the way to new diagnostic approaches, treatments for motor neurone diseases

A new genetic discovery adds weight to a theory that motor neurone degenerative diseases are caused by abnormal lipid (fat) processing pathways inside brain cells.

20 Jun 2022

Research may open door to the design of a better structured rabies vaccine

Rabies virus kills a shocking 59,000 people each year, many of them children. Some victims, especially kids, don't realize they've been exposed until it is too late.

17 Jun 2022

New discovery could lead to the development of therapeutic approaches for retinitis pigmentosa

Retinitis pigmentosa, a degenerative genetic disease of the eye, is characterized by progressive vision loss, usually leading to blindness.

17 Jun 2022

Cryo-electron microscopy structure of SARS-CoV-2 membrane protein

In a recent study posted to the bioRxiv* pre-print server, researchers illustrated the cryo-electron microscopic (cryo-EM) structure of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) membrane (M) protein in lipid nanodiscs to 3.5 angstroms (Å) resolution.

16 Jun 2022

Bruker introduces enhanced 3D holographic stimulation for optogenetics on its Ultima 2Pplus multiphoton microscope

Bruker Corporation today announced the release of the NeuraLight 3D Ultra™ module to support advanced neuroscience and optogenetics research applications on Bruker’s Ultima multiphoton microscopes.

From Bruker Nano Surfaces and Metrology 16 Jun 2022

UIC scientists identify a dynamic duo of cells in lung blood vessels

Scientists at the University of Illinois Chicago have analyzed gene expression data from more than 35,000 blood vessel cells from the lungs of mice and identified two subtypes.

14 Jun 2022

Even mild respiratory COVID can affect the brain

In a recent study published in the journal Cell, researchers explored neurological symptoms and subsequent cognitive impairment experienced by survivors of mild respiratory coronavirus disease 2019 (COVID-19).

14 Jun 2022

Molecular snapshots of the productive infectious entry pathway of SARS-CoV-2 into cells

In a recent study posted to the bioRxiv* pre-print server, researchers in the United States demonstrated that the acidic milieu of the nasal cavity is critical for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) tropism.

14 Jun 2022

Targeting macropinocytosis may be an effective therapeutic approach for hepatocellular carcinoma

Researchers from the Department of Pathology, School of Clinical Medicine, LKS Faculty of Medicine, The University of Hong Kong (HKUMed) have identified a new metabolic mechanism in liver cancer cells, by which macropinocytosis, an endocytic process, is used to engulf extracellular proteins as fuels to support the unlimited growth of hepatocellular carcinoma (HCC) in hypoxia (oxygen deprivation).

14 Jun 2022

New project seeks to develop a microscopy system for making drug interactions in the liver visible

Bielefeld University is coordinating a new EU-research project that seeks to produce microscopic liver tissue cultures that can survive for 14 days, while also using imaging methods to investigate how liver cells react to combinations of different medications.

14 Jun 2022

Microscopy News and Research

Potent antibody with a novel neutralization mechanism against SARS-CoV-2 variants

Shapeshifting behavior of E. coli may offer clues to combat urinary tract infections

Cell-based assay highlights differences in antibody neutralizing capacity for SARS-CoV-2 variants

Recombinant SARS-CoV-2 harboring double reporters for COVID-19 surveillance

A full model of the SARS-CoV-2 spike protein for studying its atomic-level dynamics by multiple microsecond simulations

Three-dimensional microscope data reveals an expanded network of interneurons in the human brain

Fragment crystallizable-altered COVID-19 antibodies efficacious across two animal models

Study unveils a precise model for the stinging organelle of starlet sea anemone

Researchers measure temperature-dependent photovoltaic external quantum efficiency to transform the future of solar cells

The possible immune-mediated mechanisms causing CNS alterations during and post-acute SARS-CoV-2 infection

Genetic discovery may pave the way to new diagnostic approaches, treatments for motor neurone diseases

Research may open door to the design of a better structured rabies vaccine

New discovery could lead to the development of therapeutic approaches for retinitis pigmentosa

Cryo-electron microscopy structure of SARS-CoV-2 membrane protein

Bruker introduces enhanced 3D holographic stimulation for optogenetics on its Ultima 2Pplus multiphoton microscope

UIC scientists identify a dynamic duo of cells in lung blood vessels

Even mild respiratory COVID can affect the brain

Molecular snapshots of the productive infectious entry pathway of SARS-CoV-2 into cells

Targeting macropinocytosis may be an effective therapeutic approach for hepatocellular carcinoma

New project seeks to develop a microscopy system for making drug interactions in the liver visible

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