Ophthalmology News and Research

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Ophthalmology is the specialized field of medicine that focuses on the health of the eye. It includes the anatomy, physiology and diseases that may affect the eye. Historically, the science of ophthalmology encompassed all aspects of visual function, both in health and in illness. Additionally, ophthalmology also includes animal eyes as ocular function and optic diseases are similar among humans and animals.

Study shows children with rare eye disease have greatest benefit from gene therapy

Scientists at Oregon Health & Science University's Casey Eye Institute and Baylor College of Medicine's Cullen Eye Institute published findings from a two-year Phase I clinical trial in the journal Ophthalmology, which showed that children had the greatest benefit from gene therapy for treatment of Leber congenital amaurosis (LCA) or severe early childhood onset retinal degeneration (SECORD).

18 Apr 2016

Survivin inhibitor with chemotherapy provides therapeutic advantage for Rb cells, tumors

Researchers at The Saban Research Institute of Children's Hospital Los Angeles (CHLA) have demonstrated that targeting survivin - a protein that inhibits apoptosis or cell death - enhances the effectiveness of chemotherapy in cells and mouse models of retinoblastoma (Rb), the most common malignant tumor of the eye in children.

18 Apr 2016

Investigators find tacrolimus to be very effective in reducing ocular symptoms of GVHD

Researchers from Massachusetts Eye and Ear/Harvard Medical School have conducted a clinical trial comparing the safety and efficacy of topical tacrolimus, an immunosuppressive therapy, and topical methylprednisolone, a steroid medication, in patients with ocular graft-versus-host-disease (GVHD) -- a complication associated with allogeneic bone marrow transplants in which the transplanted immune system's cells attack certain parts of the recipient's body, including the cornea and ocular surface.

16 Apr 2016

Removal of Dnmt1 enzyme during OPC differentiation could lead to neurological symptoms

The removal of the enzyme Dnmt1 during oligodendrocyte progenitor cell (OPC) differentiation in the central nervous system resulted in inefficient myelin formation and neurological deterioration, including loss of control of bodily movements, in mice, according to a study conducted at the Icahn School of Medicine at Mount Sinai and published today in the medical journal Cell Reports. The results could lead to a new understanding of multiple sclerosis and other myelin disorders in humans.

16 Apr 2016

Scientists reveal mechanism involved in regulation of lymphangiogenesis

After an injury to tissues, such as in organ transplantation, the body grows new lymphatic vessels in a process known as lymphangiogenesis. A new study in Nature Communications reveals a mechanism involved in the regulation of this process, specifically in corneal transplants and infectious eye disease.

13 Apr 2016

University’s blindness therapy comes a step closer following landmark licensing deal with US firm

Hundreds of thousands of people worldwide, who have a disease that can lead to blindness, could have their sight restored after The University of Manchester entered into a technology license with Seattle-based company Acucela Inc.

13 Apr 2016

University's blindness therapy comes a step closer following landmark licensing deal with US firm

13 Apr 2016

Researchers analyze post-Ebola syndrome survivors to improve ongoing treatment

Researchers from the University of Liverpool and the King's Sierra Leone Partnership are to present new findings into post-Ebola syndrome at a major European conference this week.

12 Apr 2016

Lung ultrasound may be highly effective, safe for diagnosing pneumonia in children

Lung ultrasound has been shown to be highly effective and safe for diagnosing pneumonia in children and a potential substitute for chest X-ray, according to a study conducted at the Icahn School of Medicine at Mount Sinai. Results are currently published in the medical journal Chest.

12 Apr 2016

Research suggests new pathway for preventing optic nerve damage in KPro recipients

Researchers from Massachusetts Eye and Ear/Harvard Medical School have identified inflammatory factors that cause optic neuropathy in the back of the eye following implantation of a keratoprosthesis (KPro) — similar to what glaucoma patients experience, without the rise of pressure in the eye — and have shown that blocking one of those factors, tumor necrosis factor alpha (TNFa), successfully halts the development of optic nerve damage in a mouse model.

11 Apr 2016

Two common approaches to post-operative AF equally safe, effective

Cleveland Clinic researchers, as part of the Cardiothoracic Surgical Trials Network, have found that two common approaches to post-operative atrial fibrillation - rhythm control and rate control - are equally safe and effective.

5 Apr 2016

Mount Sinai Health System recognized as 'Leaders in LGBT Healthcare Equality' by HRC Foundation

Six campuses of the Mount Sinai Health System - The Mount Sinai Hospital, Mount Sinai Beth Israel, Mount Sinai St. Luke's, Mount Sinai West (formerly known as Mount Sinai Roosevelt), Mount Sinai Queens, and New York Eye and Ear Infirmary of Mount Sinai - have been recognized as "Leaders in LGBT Healthcare Equality" by the Human Rights Campaign (HRC) Foundation, the educational arm of the country's largest lesbian, gay, bisexual and transgender (LGBT) civil rights organization.

5 Apr 2016

USC study finds coffee consumption decreases colorectal cancer risk

Whether you like your coffee black, decaf, half-caff or even instant, feel free to drink up. Researchers at the University of Southern California (USC) Norris Comprehensive Cancer Center of Keck Medicine of USC have found that coffee consumption decreases the risk of colorectal cancer.

2 Apr 2016

New test can detect early stages of sight loss in age-related macular degeneration

Researchers based at the National Institute for Health Research (NIHR) Biomedical Research Centre (BRC) at Moorfields Eye Hospital and UCL Institute of Ophthalmology, received funding from Fight for Sight and the Special Trustees of Moorfields Eye Hospital NHS Foundation Trust which has resulted in the design of a new test that can spot the first stages of sight loss in age-related macular degeneration (AMD).

30 Mar 2016

Retina Implant receives CE approval for latest Alpha AMS device

Retina Implant AG, the leading developer of subretinal implants for patients blinded by retinitis pigmentosa (RP), today announced it received CE approval of its Alpha AMS device for marketing in the European economic area.

30 Mar 2016

CCN5 protein reverses cardiac fibrosis in heart failure models

CCN5, a matricellular protein, has been found to reverse established cardiac fibrosis in heart failure models, according to a study led by Roger J. Hajjar, MD, Professor of Medicine and Director of the Cardiovascular Research Center at the Icahn School of Medicine at Mount Sinai, and Woo Jin Park, PhD, Professor of Life Sciences at the Gwangju Institute of Science and Technology, South Korea.

29 Mar 2016

Diet and lifestyle may play greater role than genetics in cataract development, severity

A diet rich in vitamin C could cut risk of cataract progression by a third, suggests a study being published online today in Ophthalmology, the journal of the American Academy of Ophthalmology. The research is also the first to show that diet and lifestyle may play a greater role than genetics in cataract development and severity.

24 Mar 2016

Mount Sinai Hospital uses M1 LUMI Bead loaded with doxorubicin for liver cancer treatment

An innovative cancer treatment made of luminescent chemotherapy-filled beads injected into tumors through the wrist is now available for patients with inoperable and difficult-to-treat liver cancer.

23 Mar 2016

USC's Keck School of Medicine researcher named recipient of NCI Outstanding Investigator Award

Distinguished Professor Jae Jung, PhD, chair of the Department of Molecular Microbiology & Immunology and the director of the University of Southern California Institute for Emerging Pathogens and Immune Diseases at the Keck School of Medicine of USC, is among this year's recipients of the National Cancer Institute Outstanding Investigator Award.

23 Mar 2016

Drugs to help energy-starved photoreceptors offers new avenue for treating AMD , MacTel

New research from Boston Children's Hospital could potentially change how doctors approach two blinding diseases: 'Wet' age-related macular degeneration (AMD), the leading cause of blindness in the elderly, and macular telangiectasia (MacTel).

15 Mar 2016

Ophthalmology News and Research

Further Reading

Study shows children with rare eye disease have greatest benefit from gene therapy

Survivin inhibitor with chemotherapy provides therapeutic advantage for Rb cells, tumors

Investigators find tacrolimus to be very effective in reducing ocular symptoms of GVHD

Removal of Dnmt1 enzyme during OPC differentiation could lead to neurological symptoms

Scientists reveal mechanism involved in regulation of lymphangiogenesis

University’s blindness therapy comes a step closer following landmark licensing deal with US firm

University's blindness therapy comes a step closer following landmark licensing deal with US firm

Researchers analyze post-Ebola syndrome survivors to improve ongoing treatment

Lung ultrasound may be highly effective, safe for diagnosing pneumonia in children

Research suggests new pathway for preventing optic nerve damage in KPro recipients

Two common approaches to post-operative AF equally safe, effective

Mount Sinai Health System recognized as 'Leaders in LGBT Healthcare Equality' by HRC Foundation

USC study finds coffee consumption decreases colorectal cancer risk

New test can detect early stages of sight loss in age-related macular degeneration

Retina Implant receives CE approval for latest Alpha AMS device

CCN5 protein reverses cardiac fibrosis in heart failure models

Diet and lifestyle may play greater role than genetics in cataract development, severity

Mount Sinai Hospital uses M1 LUMI Bead loaded with doxorubicin for liver cancer treatment

USC's Keck School of Medicine researcher named recipient of NCI Outstanding Investigator Award

Drugs to help energy-starved photoreceptors offers new avenue for treating AMD , MacTel

Event guide: The 4th Ophthalmic Drug Delivery Summit eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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