Pathology News and Research

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Pathology is the study and diagnosis of disease through examination of organs, tissues, bodily fluids, and whole bodies (autopsies). The term also encompasses the related scientific study of disease processes, called General pathology. Medical pathology is divided in two main branches, Anatomical pathology and Clinical pathology. Veterinary pathology is concerned with animal disease whereas Phytopathology is the study of plant diseases.

Pomegranate seed oil boosts brain function in mild cognitive impairment study

Study demonstrates that pomegranate seed oil (PSO) combined with the Mediterranean Diet (MeDi) significantly enhances cognitive functions in individuals with mild cognitive impairment (MCI), suggesting PSO as a potential natural intervention for cognitive health.

5 Feb 2024

Shared molecular pathways found in Alzheimer's and epilepsy

Study reveals shared brain proteomic signatures in Alzheimer’s disease and epilepsy, suggesting common molecular mechanisms that could pave the way for unified therapeutic strategies.

5 Feb 2024

Xist lncRNA identified as key trigger in female-biased autoimmune diseases

Researchers uncover that the Xist ribonucleoprotein complex, unique to females, is a key driver of sex-biased autoimmunity, offering new insights into autoimmune disorders' higher prevalence in women.

4 Feb 2024

Gut health linked to Alzheimer's progression, study suggests diet as potential therapy

Study reviews the intricate relationship between diet, gut microbiome diversity, and Alzheimer’s disease progression, suggesting gut health could play a key role in managing the disease.

3 Feb 2024

New study identifies key role of microRNA-29 in scar-free wound healing

New findings in The American Journal of Pathology, published by Elsevier, report that a class of small RNAs (microRNAs), microRNA-29, can restore normal skin structure rather than producing a wound closure by a connective tissue (scar).

2 Feb 2024

Researchers find new clue to treating aggressive Wilms tumor subtype

An international team, led by researchers at Nagoya University in Japan, may have determined why the diffuse anaplasia (DA) subtype of Wilms tumor (WT) resists chemotherapy.

2 Feb 2024

Long COVID and ME/CFS share isimilarities in immune system dysfunction, study finds

A study led by UMass Chan Medical School viral immunologists Liisa Selin, MD, PhD, and Anna Gil, PhD, discovered similarities in immune system dysfunction as a potential biomarker among people living with long COVID and myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS).

1 Feb 2024

New microscopy technology unveils detailed images of brain cancer tissue

Brigham and MIT researchers uncovered never-before-seen details in human brain tissue with new, inexpensive microscopy technology.

1 Feb 2024

Combination drug treatment could be effective against malignant peripheral nerve sheath tumors

A combination of two cancer drugs could be effective against malignant peripheral nerve sheath tumors (MPNSTs) - soft tissue tumors that are stubbornly resistant to chemotherapy and radiation - according to a laboratory study led by researchers at the Johns Hopkins Kimmel Cancer Center.

31 Jan 2024

Do deep learning tools outperform humans in diagnosing breast cancer via ultrasound imaging?

The accuracy of deep learning (DL) in diagnosing breast cancer using ultrasound (US) compared to human readers in clinical settings.

31 Jan 2024

Cadaveric pituitary-derived growth hormone delivery influences iatrogenic Alzheimer’s Disease

Recipients of cadaver-derived pituitary growth hormone (c-hGH) developed biomarker changes in the realm of Alzheimer’s disease (AD).

31 Jan 2024

XRCC1 shows potential as a prognostic and immunological pan-cancer biomarker

A new research paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 16, Issue 1, entitled, "XRCC1: a potential prognostic and immunological biomarker in LGG based on systematic pan-cancer analysis."

30 Jan 2024

Bio-Techne’s Advanced Cell Diagnostics (ACD) sets new standard in spatial biology with protease-free RNAscope multiomics

Bio-Techne Corporation (NASDAQ: TECH) today announced that Advanced Cell Diagnostics (ACD), a Bio-Techne spatial biology brand, has set a new standard with the development of a next-generation, protease-free RNAscope spatial multiomics workflow.

From Bio-Techne 30 Jan 2024

Oncofetal ecosystems linked to recurrence and immunotherapy response in liver cancer

A team of clinician-scientists and researchers from the National Cancer Centre Singapore (NCCS), Agency for Science, Technology and Research (A*STAR), the Harry Perkins Institute of Medical Research and global research partners, has found a causal link between the presence of oncofetal ecosystems (re-emergence of fetal programme/features driven by the tumor) in the primary liver cancer hepatocellular carcinoma (HCC) and cancer recurrence and response to immunotherapy.

29 Jan 2024

RNA sequencing analysis feasible for diagnosis of molecular subtypes in pediatric B-ALL

Acute lymphoblastic leukemia (ALL) is the most common childhood cancer, representing more than 30% of all pediatric cases.

29 Jan 2024

How does the nasal cavity's immune system combat SARS-CoV-2?

Researchers discovered that CD4+ and CD8+ T cells play a crucial role in clearing COVID-19 infection in the nasal cavity but have limited impact on lung infections, with implications for understanding and treating the virus.

28 Jan 2024

Revolutionary CAR T-cell therapy shows promise in reversing age-related metabolic dysfunction

study evaluates senolytic CAR T-cell therapy targeting uPAR-positive cells in aged mice, showing its effectiveness in mitigating age-related metabolic dysfunction and offering a potential long-lasting treatment for aging-associated conditions.

28 Jan 2024

Washington University School of Medicine joins collaboration to improve pediatric heart disease care

Washington University School of Medicine in St. Louis has joined the Pediatric Heart Network, a multicenter collaboration of leading hospitals and research institutions that works to improve care for pediatric heart disease patients.

25 Jan 2024

Study establishes the ideal immunosuppression regimen for pig-to-human kidney xenotransplantation

Currently used Food and Drug Administration-approved transplant drugs - with the addition of an also already FDA-approved complement inhibitor - are the optimal immunosuppression regimen for pig-to-human kidney transplants, according to a landmark discovery by University of Alabama at Birmingham investigators.

25 Jan 2024

Lunaphore and Acd Revolutionize Spatial Biology Research With the Launch of the First Fully Automated, Same-Section, Hyperplex Multiomics Application

Bio-Techne Corporation (NASDAQ: TECH) today announced that its spatial biology brands, Lunaphore and Advanced Cell Diagnostics (ACD), will launch the first fully automated spatial multiomics workflow with same-section hyperplex detection of RNA and protein biomarkers.

From Bio-Techne 25 Jan 2024

Pathology News and Research

Further Reading

Pomegranate seed oil boosts brain function in mild cognitive impairment study

Shared molecular pathways found in Alzheimer's and epilepsy

Xist lncRNA identified as key trigger in female-biased autoimmune diseases

Gut health linked to Alzheimer's progression, study suggests diet as potential therapy

New study identifies key role of microRNA-29 in scar-free wound healing

Researchers find new clue to treating aggressive Wilms tumor subtype

Long COVID and ME/CFS share isimilarities in immune system dysfunction, study finds

New microscopy technology unveils detailed images of brain cancer tissue

Combination drug treatment could be effective against malignant peripheral nerve sheath tumors

Do deep learning tools outperform humans in diagnosing breast cancer via ultrasound imaging?

Cadaveric pituitary-derived growth hormone delivery influences iatrogenic Alzheimer’s Disease

XRCC1 shows potential as a prognostic and immunological pan-cancer biomarker

Bio-Techne’s Advanced Cell Diagnostics (ACD) sets new standard in spatial biology with protease-free RNAscope multiomics

Oncofetal ecosystems linked to recurrence and immunotherapy response in liver cancer

RNA sequencing analysis feasible for diagnosis of molecular subtypes in pediatric B-ALL

How does the nasal cavity's immune system combat SARS-CoV-2?

Revolutionary CAR T-cell therapy shows promise in reversing age-related metabolic dysfunction

Washington University School of Medicine joins collaboration to improve pediatric heart disease care

Study establishes the ideal immunosuppression regimen for pig-to-human kidney xenotransplantation

Lunaphore and Acd Revolutionize Spatial Biology Research With the Launch of the First Fully Automated, Same-Section, Hyperplex Multiomics Application

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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