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Researchers isolate an IgM exhibiting ultrapotent neutralization from a Zika virus-infected pregnant woman

A recent study published in the Cell Press Journal demonstrated that plasma immunoglobulins of isotype M elicited during pregnancy have an exceptional Zika virus-neutralizing potential.

27 Mar 2023

Antifungal tolerance in Candida auris contributes to treatment failure

A recent study published in the journal Biomedicines aimed to determine the antifungal tolerance of Candida auris (C. auris) to all three classes of antifungal drugs commonly used to treat invasive candidiasis.

23 Mar 2023

Pet dogs across the USA are becoming increasingly resistant to benzimidazole treatment

In a recent study published in the journal PLOS Pathogens, researchers in the United States of America (USA) and Canada found molecular evidence that the parasitic hookworms (Ancylostoma caninum) in pet dogs across the USA are becoming increasingly resistant to benzimidazole, a broad-spectrum anthelmintic drug used for infection control.

22 Mar 2023

What is the effect of maternal obesity on the brain development of offspring?

Recently, scientists reviewed the mechanisms associated with the maternal microbiome, breast milk composition, maternal and placental metabolites, altered maternal care, and inflammation, which influences the brain development of the offspring.

22 Mar 2023

Green tea holds potential as treatment for uterine fibroids, PCOS, and menopausal symptoms

In a recent study published in the journal Nutrients, researchers at Johns Hopkins Medicine reviewed the beneficial properties of green tea in alleviating symptoms of benign gynecological disorders.

21 Mar 2023

CRISPR-based genome editing restores the vision of mice with retinitis pigmentosa

Researchers in China have successfully restored the vision of mice with retinitis pigmentosa, one of the major causes of blindness in humans.

17 Mar 2023

Bacteria require phase separation to thrive in the mammalian gut

The common commensal gut bacterium Bacteroides thetaiotaomicron uses phase separation of the transcription termination factor Rho to colonize and thrive in the mammalian gut, according to a new study in mice.

17 Mar 2023

Study suggests a novel strategy to combat multidrug-resistant S. pneumoniae infections

Pneumococcal disease leads to over three million hospitalizations and hundreds of thousands of deaths annually.

17 Mar 2023

When mass spectrometry redefines molecular biology and biochemistry – the future of spatial omics

In this interview, Bruker speaks with Ramon Sun on the topic of SpatialOMx - a field that is currently experiencing great changes. Dive in to discover how Bruker will rise to the challenge.

From Bruker Daltonics 17 Mar 2023

Does vitamin D play an anti-viral role against SARS-CoV-2?

Researchers screened various compounds for anti-viral properties against SARS-CoV-2.

17 Mar 2023

Study provides strong support for AAV.NT-3 gene therapy in the management of sarcopenia

A new research paper was published on the cover of Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 15, Issue 5, entitled, "AAV1.NT-3 gene therapy prevents age-related sarcopenia."

16 Mar 2023

Owlstone Medical Enters Partnership with Bicycle Therapeutics for the Development of Antigen-Targeted EVOC Probes for Early Cancer Detection

Owlstone Medical, the global leader in Breath Biopsy® announced that it has entered into a Research Agreement with Bicycle Therapeutics plc.

15 Mar 2023

An emerging target for chronic kidney disease treatment - DNA-PKcs

A recent Nature Communications study suggested that DNA-PKcs could be a potential target for treating chronic kidney disease.

15 Mar 2023

XBP1s plays a key role in controlling IL-15-mediated NK cell survival, study shows

A new study published in Science Immunology points to a promising therapeutic approach for future cancer treatments based on natural killer cells (NK), which are immune cells that bind to tumor cells and destroy them.

14 Mar 2023

The right combination of bile salt hydrolases may offer a new approach to treat C. diff

Not all probiotics are created equal. In a new study, researchers found that certain enzymes within a class known as bile salt hydrolases (BSHs) can restrict Clostridioides difficile (C. diff.) colonization by both altering existing bile acids and by creating a new class of bile acids within the gut's microbial environment.

13 Mar 2023

Research examines the use of Brillouin microscopy to improve acquisition speed, reduce irradiation doses

Diagnostic imaging offers physicians and scientists critical visual representations of internal body structures, greatly enhancing clinical analysis and medical intervention.

10 Mar 2023

Magnetic soft-robotic chains that can be reconfigured into programmable shapes show potential applications in improving minimally invasive surgery

Researchers presented magnetic soft-robotic chains that use magnetic and elastic energies to fold themselves into large stable assemblies compatible with magnetic navigational technologies and have potential applications in improving minimally invasive surgery.

10 Mar 2023

Researchers develop an implantable sensor for monitoring overactive bladders

Modern living seems to have exacerbated the conditions of our gut. There is an escalating prevalence of irritable bowel syndrome and overactive bladder syndrome among individuals who do not exhibit signs of infectious maladies or other established ailments, but rather report experiencing sudden symptoms.

9 Mar 2023

Inhibition of ACLY by 326E represents a promising strategy for treatment of hypercholesterolemia

This new article publication from Acta Pharmaceutica Sinica B, discusses the development of the novel ACLY inhibitor 326E as a promising treatment for hypercholesterolemia.

9 Mar 2023

Nasal administration of a fully human anti-CD3 monoclonal antibody modulates T cell inflammatory responses in COVID-19

Researchers assessed the impact of an anti-CD3 monoclonal antibody called Foralumab in COVID-19 treatment.

9 Mar 2023

in vivo News and Research

Researchers isolate an IgM exhibiting ultrapotent neutralization from a Zika virus-infected pregnant woman

Antifungal tolerance in Candida auris contributes to treatment failure

Pet dogs across the USA are becoming increasingly resistant to benzimidazole treatment

What is the effect of maternal obesity on the brain development of offspring?

Green tea holds potential as treatment for uterine fibroids, PCOS, and menopausal symptoms

CRISPR-based genome editing restores the vision of mice with retinitis pigmentosa

Bacteria require phase separation to thrive in the mammalian gut

Study suggests a novel strategy to combat multidrug-resistant S. pneumoniae infections

When mass spectrometry redefines molecular biology and biochemistry – the future of spatial omics

Does vitamin D play an anti-viral role against SARS-CoV-2?

Study provides strong support for AAV.NT-3 gene therapy in the management of sarcopenia

Owlstone Medical Enters Partnership with Bicycle Therapeutics for the Development of Antigen-Targeted EVOC Probes for Early Cancer Detection

An emerging target for chronic kidney disease treatment - DNA-PKcs

XBP1s plays a key role in controlling IL-15-mediated NK cell survival, study shows

The right combination of bile salt hydrolases may offer a new approach to treat C. diff

Research examines the use of Brillouin microscopy to improve acquisition speed, reduce irradiation doses

Magnetic soft-robotic chains that can be reconfigured into programmable shapes show potential applications in improving minimally invasive surgery

Researchers develop an implantable sensor for monitoring overactive bladders

Inhibition of ACLY by 326E represents a promising strategy for treatment of hypercholesterolemia

Nasal administration of a fully human anti-CD3 monoclonal antibody modulates T cell inflammatory responses in COVID-19

eBook: Using iPSCs models for human disease research and drug discovery eBook

Lab Matters host Harriet Gould on building a more connected lab community

The Critical Role of Sample Storage in Drug Discovery and Development

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

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