in vivo News and Research

RSS

Researchers develop a potential treatment for autoimmune encephalitis

In autoimmune encephalitis, a rare but serious and sometimes life-threatening inflammation of the central nervous system, the body's own defenses are directed against the central nervous system.

3 Mar 2023

Study identifies the essential genetic and immunologic perturbations occurring in patients with long COVID lung fibrosis

Researchers elucidated immunologic and genetic perturbations in long COVID patients with pulmonary fibrosis.

3 Mar 2023

New delivery system based on lipid nanoparticles could increase the efficiency of gene therapy

Lipid nanoparticles have been used to encapsulate CRISPR-Cas9 and deliver it to cells in mice, where it was highly effective at knocking down expression of a target protein.

2 Mar 2023

Role of phosphatidylinositol 3 kinase pathway in corneal damage due to blue light exposure

Researchers observe corneal damage by blue light exposure is due to PI3K/AKT pathway inhibition.

1 Mar 2023

New cell-based assay shown to rapidly profile drug resistance to three widely used SARS-CoV-2 main protease inhibiting drugs

In a recent study posted to the bioRxiv* pre-print server, researchers tested three next-generation severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) main protease (Mpro) inhibitors, namely, nirmatrelvir, ensitrelvir, and FB2001, using a novel cell-based assay.

1 Mar 2023

Study reveals synergistic impact of estrogen and intestinal dysbiosis on pulmonary fibrosis

In a recent study published in Cells, researchers evaluated idiopathic pulmonary fibrosis (IPF) pathophysiological differences by sex and intestinal microbiome.

1 Mar 2023

New imaging method could help make better decisions on personalized cancer treatment

Decisions on cancer treatment could become better tailored to individual patients with the adoption of a new imaging method being developed by University of Michigan researchers that maps the chemical makeup of a patient’s tumor.

1 Mar 2023

Antiverse raises funding and demonstrates therapeutic antibody identification with AI-driven drug discovery platform

Antiverse Ltd (Antiverse), a biotechnology company developing a computational antibody drug discovery platform, today announced the successful identification of functional antibody clusters targeting two G-protein-coupled receptors (GPCRs), both displaying versatile binding profiles and nanomolar affinity.

From Antiverse 1 Mar 2023

Product development and drug delivery at Seda

In this interview, NewsMedical speaks with Shanoo about her career progression and role in Seda Pharmaceutical regarding product development and drug delivery. She also outlines some of the services that Seda offers.

From Seda Pharmaceutical Development Services 1 Mar 2023

New funding to accelerate development of potential anti-cancer compound into the clinic

For the past few decades, Dr. Iwao Ojima has been working in his Stony Brook University Department of Chemistry Laboratory and through the Institute of Chemical Biology & Drug Discovery (ICB&DD) to develop next-generation anti-cancer agents.

28 Feb 2023

CN Bio extends microphysiological system portfolio with PhysioMimix Single-Organ Higher Throughput System

CN Bio, a leading Organ-on-a-Chip (OOC) company that designs and manufactures single-and multi-organ microphysiological systems (MPS), today announced the commercial launch of the PhysioMimix™ Single-organ Higher Throughput (HT) System.

From CN Bio 28 Feb 2023

Natural product with grape seed extracts, lactic acid, and pea protein could effectively manage bacterial vaginosis

Researchers evaluate the efficacy of using a product comprising lactic acid, grape seed extract, and pea protein in managing bacterial vaginosis in vivo.

28 Feb 2023

What is the effect of maternal circulating amino acids on offspring birthweight?

Researchers examined the effect of serum levels of 20 amino acids in a mother during pregnancy on offspring birthweight in a two-sample summary data Mendelian randomization framework.

27 Feb 2023

Experts develop commercial formulation Campto for colorectal cancer

Announcing a new publication for Acta Materia Medica journal. The compound 7-ethyl-10-hydroxy-camptothecin (SN38) is a broad-spectrum antitumor agent whose applications are greatly limited by its poor solubility. Therefore, irinotecan, the hydrophilic derived prodrug of SN38, has been developed as the commercial formulation Campto® for colorectal cancer.

25 Feb 2023

Study findings likely to guide the design of engineered TAPBPR variants with tailored HLA specificity

Researchers at Children's Hospital of Philadelphia (CHOP) have identified variants of a chaperone molecule that optimizes the binding and presentation of foreign antigens across the human population, which could open the door to numerous applications where robust presentation to the immune system is important, including cell therapy and immunization. The findings were published today in Science Advances.

24 Feb 2023

Researchers successfully grow electrodes in living tissues

The boundaries between biology and technology are becoming blurred. Researchers at Linköping, Lund, and Gothenburg universities in Sweden have successfully grown electrodes in living tissue using the body's molecules as triggers.

24 Feb 2023

Fixation Before Dissociation Using a Deep Eutectic Solvent Preserves In Vivo States and Phospho-Signalling in Single-Cell Sequencing Presented

Researchers at the University of Alabama at Birmingham have demonstrated a novel way of fixing cells and preserving their biomolecules prior to single cell dissociation without the need for harsh enzymatic/mechanical approaches.

From Rapid Labs Ltd 24 Feb 2023

in vivo News and Research

Researchers develop a potential treatment for autoimmune encephalitis

Study identifies the essential genetic and immunologic perturbations occurring in patients with long COVID lung fibrosis

New delivery system based on lipid nanoparticles could increase the efficiency of gene therapy

Role of phosphatidylinositol 3 kinase pathway in corneal damage due to blue light exposure

New cell-based assay shown to rapidly profile drug resistance to three widely used SARS-CoV-2 main protease inhibiting drugs

Study reveals synergistic impact of estrogen and intestinal dysbiosis on pulmonary fibrosis

New imaging method could help make better decisions on personalized cancer treatment

Antiverse raises funding and demonstrates therapeutic antibody identification with AI-driven drug discovery platform

Product development and drug delivery at Seda

New funding to accelerate development of potential anti-cancer compound into the clinic

CN Bio extends microphysiological system portfolio with PhysioMimix Single-Organ Higher Throughput System

Natural product with grape seed extracts, lactic acid, and pea protein could effectively manage bacterial vaginosis

What is the effect of maternal circulating amino acids on offspring birthweight?

Experts develop commercial formulation Campto for colorectal cancer

Study findings likely to guide the design of engineered TAPBPR variants with tailored HLA specificity

Researchers successfully grow electrodes in living tissues

Fixation Before Dissociation Using a Deep Eutectic Solvent Preserves In Vivo States and Phospho-Signalling in Single-Cell Sequencing Presented

NQO2 gene as a novel potential target in Parkinson’s disease

New prototype treatment proves effective against the venom of African and Asian elapid snakes

Researchers report the circulation of a novel MERS-like coronavirus in Malayan pangolins

Human iPSCs: A Full Guide to Advanced in Vitro Models and Applications eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Latest News