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Experimental Alzheimer’s drugs show promise

Researchers from Salk have found that two experimental drugs named CMS121 and J147 may improve memory functions and reduce the progression of memory decline and brain degeneration in mice models of Alzheimer’s disease (AD). The researchers published their work in the latest issue of the journal eLife. The study was titled, “Elevating acetyl-CoA levels reduces aspects of brain aging.”

11 Dec 2019

Genetic code doesn't dictate whether a person is guaranteed to develop Alzheimer's

The colour of our eyes or the straightness of our hair is linked to our DNA, but the development of Alzheimer's disease isn't exclusively linked to genetics, suggest recently published findings.

11 Dec 2019

Scientists evaluate mouse models used for developing new treatments for Huntington's disease

Huntington's disease (HD) is an incurable and fatal hereditary disease. Developing disease-modifying drugs to treat patients with HD depends on studying them in animal models. Scientists evaluated the mouse models used for developing new treatments for mood disorders in HD and recommended which of these models are most relevant to their studies.

11 Dec 2019

Study could help improve GENUS to become a therapeutic approach for Alzheimer's disease

The sweeping extent to which increasing 40Hz "gamma" rhythm power in the brain can affect the pathology and symptoms of Alzheimer's disease in mouse models has been surprising, even to the MIT neuroscientists who've pioneered the idea. So surprising, in fact, they can't yet explain why it happens.

11 Dec 2019

New therapy shows dramatic effect against worst types of leukaemias

A collaborative research effort by Australian and US scientists has led to the discovery of a promising new approach to treating some of the worst types of leukaemia, including an aggressive leukaemia that mostly affects babies.

11 Dec 2019

Low-dose aspirin not associated with reduced risk of heart attack among African Americans

Low-dose aspirin was not associated with a reduced risk of a fatal heart attack among African Americans, according to an observational study published in the Journal of the American Heart Association, the open access journal of the American Heart Association.

11 Dec 2019

Researchers use stem cells to create in-vitro 3D neural tissue model

Researchers at the University of Illinois at Urbana-Champaign have successfully used stem cells to engineer living biohybrid nerve tissue to develop 3D models of neural networks with the hopes of gaining a better understanding of how the brain and these networks work.

11 Dec 2019

Blood test could be a better way of guiding treatment for advanced breast cancer patients

A blood test can help identify rare mutations in advanced breast cancer, which may enable patients to access effective treatments more quickly in the future, Cancer Research UK scientists have found.

11 Dec 2019

DNA site GEDmatch sold to forensic genomics firm

A DNA site has been bought by a forensic genomics firm, prompting discussion over future use of genetic data in solving crime.

11 Dec 2019

Stilla Technologies announces key leadership hires

Stilla Technologies, the provider of pioneering digital PCR solutions for high-precision genetic analysis, today announced three key hires: Khaled Bahi joins as CFO, with Jerome Leclercq named Senior Vice President for Commercial Operations Europe & Asia and Quang Tran named Quality & Regulatory Affairs Director.

11 Dec 2019

Genetic variant mainly found in individuals of African ancestry increases odds of heart failure

A genetic variant in the gene transthyretin (TTR)- which is found in about 3 percent of individuals of African ancestry- is a more significant cause of heart failure than previously believed, according to a multi-institution study led by researchers at Penn Medicine.

10 Dec 2019

Online decision aid provides more knowledge about the benefits of genomic sequencing

A decision aid developed to support patients undergoing genomic sequencing can reduce the amount of time patients spend speaking with overburdened genetic counselors while helping them were more knowledgeable about the benefits of sequencing, suggests a study from St. Michael's Hospital.

10 Dec 2019

Huntington's disease patients need to better understand the risks and benefits of new therapies

For patients with Huntington's disease (HD), clinical trials can offer hope when there are no treatments available despite unknowns about whether the therapy will work or is safe.

10 Dec 2019

Researchers find another piece of puzzle relating to bird flu viruses

Normally, bird flu viruses do not spread easily from person to person. But if this does happen, it could trigger a pandemic. Researchers from the MDC and RKI have now explained in the journal Nature Communications what makes the leap from animals to humans less likely.

10 Dec 2019

Modifier gene offers a likely explanation for less infection in some patients with cystic fibrosis

Cystic fibrosis is caused by an inherited mutation in the cystic fibrosis transmembrane conductance regulator (CFTR) gene.

10 Dec 2019

Study provides most detailed classification of acute myeloid leukemia, myelodysplastic syndrome

Results from a study conducted by St. Jude Children's Research Hospital and the Munich Leukemia Laboratory were presented today as a late-breaking abstract at the American Society of Hematology annual meeting. The study integrates genomic and transcriptomic sequencing to provide the most detailed classification of acute myeloid leukemia (AML) and myelodysplastic syndrome (MDS) to date.

10 Dec 2019

Researchers aim to exploit DNA mutations in the treatment of blood and bone marrow cancers

In a clinical trial led by Yale Cancer Center and Smilow Cancer Hospital, researchers aim to exploit DNA mutations in the treatment of two blood and bone marrow cancers, a different tacit than the more traditional approach of blunting or switching off genetic mutations linked to cancer.

10 Dec 2019

ERC promotes CRISPR research to better treat infections

Chase Beisel heads the "Synthetic Biology of RNA" research group at the Helmholtz Institute for RNA-based Infection Research (HIRI) in Würzburg, a branch of the Helmholtz Centre for Infection Research in Braunschweig and run in collaboration with the Julius-Maximilians-Universität in Würzburg.

10 Dec 2019

Researchers discover a widespread method used by phages to hide from bacterial defenses

University of Otago researchers have discovered how viruses that specifically kill bacteria can outwit bacteria by hiding from their defenses, findings which are important for the development of new antimicrobials based on viruses and provide a significant advance in biological knowledge.

10 Dec 2019

Transplant patient finds out his DNA has been replaced by that of his donor

A bone marrow transplant recipient later found out that the DNA in his blood and semen had been replaced by that of his donor.

10 Dec 2019

Genetic News and Research

Experimental Alzheimer’s drugs show promise

Genetic code doesn't dictate whether a person is guaranteed to develop Alzheimer's

Scientists evaluate mouse models used for developing new treatments for Huntington's disease

Study could help improve GENUS to become a therapeutic approach for Alzheimer's disease

New therapy shows dramatic effect against worst types of leukaemias

Low-dose aspirin not associated with reduced risk of heart attack among African Americans

Researchers use stem cells to create in-vitro 3D neural tissue model

Blood test could be a better way of guiding treatment for advanced breast cancer patients

DNA site GEDmatch sold to forensic genomics firm

Stilla Technologies announces key leadership hires

Genetic variant mainly found in individuals of African ancestry increases odds of heart failure

Online decision aid provides more knowledge about the benefits of genomic sequencing

Huntington's disease patients need to better understand the risks and benefits of new therapies

Researchers find another piece of puzzle relating to bird flu viruses

Modifier gene offers a likely explanation for less infection in some patients with cystic fibrosis

Study provides most detailed classification of acute myeloid leukemia, myelodysplastic syndrome

Researchers aim to exploit DNA mutations in the treatment of blood and bone marrow cancers

ERC promotes CRISPR research to better treat infections

Researchers discover a widespread method used by phages to hide from bacterial defenses

Transplant patient finds out his DNA has been replaced by that of his donor

Sequencing & Genomics: Elevating Science and Healthcare eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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