Molecule News and Research

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New instrumentation to help fight obesity and diabetes

World-first equipment, made exclusively for UQ scientists, will determine how to produce food which is better for us, but still tastes good.

12 Sep 2007

Potential new drug target for preventing postmenopausal bone loss

Scientists have discovered new information about an immune pathway in mice that explains how oxidative stress that results from acute estrogen deficiency leads to the loss of bone.

11 Sep 2007

Scientists identify process that causes blood vessels to constrict during and after a heart attack

They've also demonstrated that delivering a vital molecule that is depleted during this process directly to those blood vessels can reverse damage and help restore blood flow.

11 Sep 2007

Novel enzyme may offer huge range of potential therapeutic agents

By guiding an enzyme down a new evolutionary pathway, a team of University of Wisconsin-Madison researchers has created a new form of an enzyme capable of producing a range of potential new therapeutic agents with anticancer and antibiotic properties.

10 Sep 2007

Researchers develop mouse model of autism spectrum disorders

Howard Hughes Medical Institute researchers have genetically engineered mice that harbor the same genetic mutation found in some people with autism and Asperger syndrome.

10 Sep 2007

Mutated mice provide new insights into autism

Mice containing a mutated human gene implicated in autism exhibit the poor social skills but increased intelligence akin to the title character's traits in the movie “Rain Man,” researchers at UT Southwestern Medical Center have found.

10 Sep 2007

A molecular probe that may one day light up tumors while surgery is in progress

Researchers at the Stanford University School of Medicine have developed a molecular probe that sets aglow tumor cells within living animals. Their goal is to use the probe to improve the diagnosis and treatment of cancer and other diseases.

10 Sep 2007

Metformin could potentially improve pregnancy outcomes in women with insulin resistance

Women who are obese, have type 2 diabetes or a family history of type 2 diabetes could one day have more successful pregnancies because of a study at Washington University School of Medicine in St. Louis.

10 Sep 2007

New method to create natural drug products

Until now, only the intricate machinery inside cells could take a mix of enzyme ingredients, blend them together and deliver a natural product with an elaborate chemical structure such as penicillin.

5 Sep 2007

Low level of neuronal receptor LR11 linked to Alzheimer's disease

Results of a new study indicate a strong link between the loss of the neuronal receptor LR11and onset of mild cognitive impairment (MCI), often a harbinger of Alzheimer's disease.

5 Sep 2007

N-acetylcysteine may not be as safe as once thought

Certain preparations taken to enhance athletic performance or stave off disease contain an anti-oxidant that could cause harm.

5 Sep 2007

Study identifies osteopontin as a key player in the body's immune response to chronic stress

Osteopontin (OPN), a protein molecule involved in many different cellular processes, plays a significant role in immune deficiency and organ atrophy following chronic physiological stress, resulting in increased susceptibility to illness.

4 Sep 2007

Retinoblastoma tumor suppressor may predict chemotherapy effectiveness

A common molecular pathway could help physicians predict which lung cancer patients will benefit from chemotherapy drugs, according to new research from a multidisciplinary team at the University of Cincinnati (UC).

3 Sep 2007

Cell that triggers symptoms in allergy attacks can also limit damage

A blood cell known as a troublemaker for triggering the itch and inflammation in allergy attacks, the mast cell, can also calm down the flare-ups, researchers from Stanford University School of Medicine have found.

3 Sep 2007

Does physical activity provide a molecular key to longevity?

Fitness and physical exercise are among the most neglected means to improve prognosis. They are the healthiest cardiovascular intervention. Even cardiologists focus on pharmacological treatment and evaluate classical risk factors without asking about daily exercise or objective measures of physical capacity. It is surprising considering the strong data that underscores the survival benefit of regular exercise training.

2 Sep 2007

Brain's impaired ability to sense glucose might play role in type 2 diabetes

New findings from studies in mice suggest that defects in the brain's ability to respond to glucose play a role in the development of non-insulin dependent (type 2) diabetes, and that a high-fat diet may contribute to impairing brain cells' ability to regulate glucose throughout the body.

30 Aug 2007

Researchers unlock mystery of a third olfactory system

Researchers at the University of Maryland School of Medicine have found a "nose within the nose," a unique olfactory system within the noses of mice that is able to "smell" hormones involved in regulating water and salt balance in the body.

30 Aug 2007

Researchers dispute immortal strand hypothesis

How do adult stem cells protect themselves from accumulating genetic mutations that can lead to cancer?

30 Aug 2007

FDA grants orphan drug designation to TREANDA

Cephalon, Inc. announced today that the U.S. Food and Drug Administration (FDA) Office of Orphan Products Development granted orphan drug designation for the company's investigational therapy, TREANDA (bendamustine HCl), for the treatment of chronic lymphocytic leukemia (CLL).

29 Aug 2007

Secret to bone's strength

Scientists and engineers are eager to understand the secret behind bone's lightweight toughness so they can mimic it in the design of new materials, but previous studies have revealed a number of different strength mechanisms at different scales of focus, rather than a single theory.

28 Aug 2007