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DNA, or deoxyribonucleic acid, is the hereditary material in humans and almost all other organisms. Nearly every cell in a person’s body has the same DNA. Most DNA is located in the cell nucleus (where it is called nuclear DNA), but a small amount of DNA can also be found in the mitochondria (where it is called mitochondrial DNA or mtDNA).

Urinary microbiota implicated in overactive bladder

Contrary to popular belief, urine is not sterile and contains a range of microbiological organisms that vary in health and disease, US scientists have shown.

5 Jun 2014

Data from Caris Registry clinical outcomes presented at ASCO annual meeting

Caris Life Sciences and investigators from Inova Fairfax Hospital presented the first clinical outcomes data presentation from the Caris Registry™ at the 50th annual meeting of the American Society of Clinical Oncology (ASCO) in Chicago, Ill., this weekend.

5 Jun 2014

Whole genome sequencing reveals severe intellectual disability in patients

With a new technique, which at once studies the whole genome, a genetic cause can be identified in six out of ten children with severe intellectual disability. This makes the method more successful than all the usual methods together.

5 Jun 2014

Thermo Fisher, Cellectis sign agreements on TALEN gene editing technology

Cellectis, a leader of engineered CART cell therapies, and Thermo Fisher Scientific announced today that they have entered into a series of agreements covering the uses of TAL nucleases under the brand name TALEN™.

5 Jun 2014

Scientists reproduce chromosomal modifications in human cells that cause certain cancer

Scientists at the Centro Nacional de Investigaciones Cardiovasculares (CNIC) and the Centro Nacional de Investigaciones Oncol-gicas (CNIO) have succeeded in reproducing, in human cells, the chromosomal translocations that cause two types of cancer: acute myeloid leukemia and Ewing's sarcoma.

5 Jun 2014

Four new genes cause inherited breast cancer risk

Four new genes have been added to the growing list of those known to cause increased breast cancer risk when mutated through the efforts of researchers at Huntsman Cancer Institute (HCI) at the University of Utah, who lead an international consortium working to find more gene mutations that cause inherited breast cancer susceptibilities.

5 Jun 2014

Cannabis use affects size and shape of sperm in young men

Young men who use cannabis may be putting their fertility at risk by inadvertently affecting the size and shape of their sperm according to research published today (Thursday 5 June 2014).

5 Jun 2014

Researchers investigate correlation between lower back pain and genes

Lower back pain is a broad yet subtle subject. It has widely been associated with early degeneration of the discs of the human spine.

4 Jun 2014

European researchers explore new tools for prevention of back pain

European researchers and clinicians are working hand in hand to unveil the mechanisms leading to back pain, likely the most widespread chronic pathology among humans. Until recently, it was assumed that disc degeneration was the main process behind back pain. The intervertebral discs are joints made of soft and very strain resistant material, placed between the vertebrae of the spine.

4 Jun 2014

Researchers reproduce tumor chromosomal translocations in human cells

Scientists from the Spanish National Cancer Research Centre and the Spanish National Cardiovascular Research Centre have been able to reproduce, for the first time in human cells, chromosomal translocations associated with two types of cancer: acute myeloid leukaemia and Ewing's sarcoma.

4 Jun 2014

Researchers reveal potential new drug target for dementia

Researchers at King's College London have discovered how a molecular 'scaffold' which allows key parts of cells to interact, comes apart in dementia and motor neuron disease, revealing a potential new target for drug discovery.

4 Jun 2014

UK makes £5.64M investment in most advanced crystallography technology

The UK's structural biology community will have access to the most advanced crystallography technology in the world thanks to a - £5.64M investment from UK research funders.

3 Jun 2014

Eppendorf announces new addition to BioBLU Single-use Vessel Adaptor Kit portfolio

Eppendorf is proud to announce a new addition to the BioBLU Single-use Vessel Adaptor Kit portfolio. The BioBLU 5c and 14c Adaptor Kits allow BioBLU 5c and 14c Single-use vessels to be used on and controlled by Sartorius® BioStat® B-DCU-II controllers (Heat Blanket configuration only).

3 Jun 2014

Metformin drug slows ageing and increases lifespan

A study by Belgian doctoral researcher Wouter De Haes (KU Leuven) and colleagues provides new evidence that metformin, the world's most widely used anti-diabetic drug, slows ageing and increases lifespan.

3 Jun 2014

CHLA researchers develop novel NextGen sequencing approach for retinoblastoma

Researchers at Children's Hospital Los Angeles have developed a unique next-generation sequencing test for the gene linked to retinoblastoma. The new approach is both more comprehensive and can be conducted in less time than existing tests - enabling early detection of the cancer's genetic cause, which is critical for optimal treatment outcomes.

3 Jun 2014

Variations in BRCA2 and CHEK2 genes can increase lung cancer risk, study finds

New research confirms a vulnerability to lung cancer can be inherited and implicates the BRCA2 gene as harboring one of the involved genetic mutations.

3 Jun 2014

Study uncovers marijuana's potential to treat autoimmune diseases

A team of University of South Carolina researchers led by Mitzi Nagarkatti, Prakash Nagarkatti and Xiaoming Yang have discovered a novel pathway through which marijuana can suppress the body's immune functions. Their research has been published online in the Journal of Biological Chemistry.

3 Jun 2014

Updated data from ImmunoCellular ICT-107 trial in patients with newly diagnosed GBM presented at ASCO 2014

ImmunoCellular Therapeutics, Ltd. announced that updated efficacy and safety data from the phase II trial of dendritic cell-based immunotherapeutic vaccine ICT-107 in patients with newly diagnosed glioblastoma multiforme (GBM) were presented at the 2014 American Society for Clinical Oncology (ASCO) annual meeting in Chicago.

2 Jun 2014

Compound in saliva may protect from toxins in tea, coffee and liquid smoke flavoring

A compound in saliva, along with common proteins in blood and muscle, may protect human cells from powerful toxins in tea, coffee and liquid smoke flavoring, according to results of a new study led by investigators at the Johns Hopkins Kimmel Cancer Center.

2 Jun 2014

Immune system-boosting therapy slows recurrence of glioblastoma multiforme

A multicenter team of investigators, led by researchers from the Cedars-Sinai Department of Neurosurgery, the Cedars-Sinai Maxine Dunitz Neurosurgical Institute and Dana-Farber Cancer Institute in Boston, have found in a Phase II clinical trial that an immune system-boosting therapy slowed the recurrence of glioblastoma multiforme, or GBM, the most common and deadly malignant brain tumor.

2 Jun 2014