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Alzheimer's-associated enzyme beta-secretase can disrupt neural activity in the brain

An enzyme involved in the formation of the amyloid-beta protein associated with Alzheimer's disease can also alter the mechanism by which signals are transmitted between brain cells, the disruption of which can cause seizures.

19 Jun 2007

Wurst protein plays a decisive role in breathing

A newly discovered transmembrane protein called "Wurst" (sausage) appears to play a decisive role in breathing ? possibly in all animals, from flies to human beings.

18 Jun 2007

Antitumor vaccine

How can we induce the body to use its own weapon, the immune system, to battle cancer" In principle, by the same means used against infectious diseases: immunization.

18 Jun 2007

New area of stroke drug discovery for the 22nd century

A new therapy to re-activate silenced genes in patients who suffer from neurodegenerative diseases or stroke is being developed by researchers at the University of Illinois at Chicago and Cornell University.

17 Jun 2007

Impaired anti-inflammatory response plays role in pathology of type 2 diabetes

Type 2 diabetes is classified as a metabolic disorder, but a growing number of researchers are beginning to think of it also as a disease of the innate immune system. Inflammation, a key component of the early immune response, is chronically elevated in people with type 2 diabetes.

17 Jun 2007

25,000 genes that have clocks!

A chemical signal acts as time clock in the expression of genes controlled by a master gene called a coactivator, said Baylor College of Medicine researchers in a report that appears in the journal Cell today.

17 Jun 2007

Biomoda files patent protection for lung cancer detection technology

Biomoda, Inc. has disclosed that it is again expanding its intellectual property portfolio with an additional unique patent pending to enhance the stability and greatly increase the shelf-life of its assay.

17 Jun 2007

Stress and Alzheimer's disease

Subjecting mice to repeated emotional stress, the kind we experience in everyday life, may contribute to the accumulation of neurofibrillary tangles, one of the hallmarks of Alzheimer's disease, report researchers at the Salk Institute for Biological Studies.

17 Jun 2007

Tumor vessels identified by unique molecular markers

Results from a new study have made it easier for scientists to distinguish between growing blood vessels in healthy tissues and those that are associated with tumors.

16 Jun 2007

Newly found antibodies may be body's natural defense against Alzheimer's

In an important advance in the battle against Alzheimer's disease, physician-scientists at NewYork-Presbyterian Hospital/Weill Cornell Medical Center have identified naturally occurring antibodies in human blood that may help to defend against this form of dementia as well as other neurodegenerative diseases.

14 Jun 2007

What makes people susceptible to rheumatoid arthritis?

Peter K. Gregersen, MD, stares at x-rays of hands, searching out the telltale signs of inflamed joints and wrists from his research subjects with rheumatoid arthritis. With these clinical features at his side, he turns to the basic building blocks of life , the human genome , to figure out what makes these people susceptible to the disabling inflammatory condition.

14 Jun 2007

New contributor to aggressive cancers

Mutations in the cell adhesion molecule known as integrin alpha 7 (integrin 7) lead to unchecked tumor cell proliferation and a significantly higher incidence in cancer spread, or metastasis, in several cancer cell lines, report researchers at the University of Pittsburgh School of Medicine in a study published in the Journal of the National Cancer Institute.

8 Jun 2007

Researchers reprogram normal tissue cells into embryonic stem cells

Researchers at the Institute for Stem Cell Biology and Medicine at UCLA were able to take normal tissue cells and reprogram them into cells with the same unlimited properties as embryonic stem cells, the cells that are able to give rise to every cell type found in the body.

8 Jun 2007

Researchers turn normal tissue cells into embryonic stem cells

8 Jun 2007

New understanding of anti-malarial drug resistance

Researchers at Georgetown University Medical Center say they are moving closer to understanding why the most lethal form of human malaria has become resistant to drug treatment in the past three decades.

8 Jun 2007

In mice, drug protects against diabetes and atherosclerosis

Blocking a single protein with an experimental drug prevented and treated both type 2 diabetes and atherosclerosis in laboratory mice that had been fed unhealthy diets and were genetically predisposed to these common killers, according to an article published online in Nature.

8 Jun 2007