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SARS-CoV-2-specific IgM / IgG responses accurately predict COVID-19 outcome

Researchers from the Huazhong University of Science and Technology and Shanghai Jiao Tong University, China, recently built a proteome microarray with 20 out of the 28 predicted SARS-CoV-2 proteins to help understand IgM/IgG responses specific to SARS-CoV-2.

17 Nov 2020

Study shows limited influence of BMI on shaping SARS-CoV-2 antibody responses

A new study by researchers at the Harvard Medical School and the Ragon Institute of MGH, MIT and Harvard showed that obesity is not tied to the increased risk of SARS-CoV-2 infection. However, the team demonstrated that obesity is associated with increased manifestations of symptoms in mild COVID-19 infections, suggesting that obesity impacts the pathophysiology of COVID-19.

16 Nov 2020

Google searches for COVID-19 symptoms can anticipate case numbers

Google searches may come to the aid in predicting the evolution of the COVID-19 pandemic, which we need to identify, manage, and, if possible, contain new outbreaks.

16 Nov 2020

Xylitol and grapefruit seed extract nasal spray could help COVID-19 patients

United States based researchers have published a report exploring the potential role of Xylitol and Grapefruit seed extract (in the form of a nasal spray) in treating COVID-19.

16 Nov 2020

Study sheds new light on the immune system response to COVID-19

A team of immunology experts from research organizations in Belgium and the UK has come together to apply their pioneering research methods to put individuals' COVID-19 responses under the microscope.

16 Nov 2020

Antiviral immune response is suppressed in COVID-19 patients compared to flu patients

Rather than life-threatening hyperinflammation, most adults with moderate-to-severe COVID-19 have a suppressed viral immune response when compared to adults with another viral respiratory infection, influenza. St. Jude Children's Research Hospital and Washington University School of Medicine in St. Louis led research that suggests most COVID-19 patients are not candidates for treatment with steroids such as dexamethasone.

16 Nov 2020

Study explains why anti-inflammatory drugs benefit only few people with severe COVID-19

The turning point for people with COVID-19 typically comes in the second week of symptoms. As most people begin to recover, a few others find it increasingly difficult to breathe and wind up in the hospital.

16 Nov 2020

Researchers use aerosolized molecules to shut down proteins generated by coronavirus

Researchers at Georgetown University Medical Center have successfully used molecules comprised of small strands of RNA to shut down the production of destructive proteins generated by the COVID-19 virus.

16 Nov 2020

PARP inhibitor, stenoparib inhibits pre- and post-entry processes of SARS-CoV-2 in vitro

A team of researchers from the Northern Arizona University evaluated a new PARP inhibitor, stenoparib, which has recently advanced to Stage II of clinical trials to treat ovarian cancer. Their study, an initial report on in vitro stenoparib activity against human coronaviruses such as SARS-CoV-2, has been published on the preprint server bioRxiv*.

15 Nov 2020

Strategizing pediatric healthcare preparedness for the second wave of the COVID-19 pandemic

The paper, put together by a team of scientists based in the United Kingdom and Italy, also underscored the need for healthcare policies to account for the very real possibility of inadequate protective personal equipment (PPE), staff and hospital capacity, aggravated by the increased number of pediatric infections.

15 Nov 2020

Drugs targeting neutrophils could reduce ARDS in severe COVID-19

Scientists in Taiwan recently published a report on their use of anti-neutrophil strategies to treat acute respiratory distress syndrome (ARDS) – a life-threatening condition that can arise in critical COVID-19 cases – in the journal Frontiers in Pediatrics.

15 Nov 2020

MIT researchers unravel the molecular structure of key coronavirus protein

MIT chemists have determined the molecular structure of a protein found in the SARS-CoV-2 virus. This protein, called the envelope protein E, forms a cation-selective channel and plays a key role in the virus's ability to replicate itself and stimulate the host cell's inflammation response.

12 Nov 2020

SARS-CoV-2-induces temporary loss of smell in mice

Now, a new study published on the preprint server bioRxiv in November 2020 presents the onset of olfactory dysfunction (loss of smell) in mice infected with the virus, examining this process at the cellular level. In doing so, this study throws more light on this curious symptom and COVID-19’s manifestations outside the lungs.

12 Nov 2020

Modeling suggests lower COVID-19 cases in Lombardy's second wave

Researchers found a negative association between the number of excess deaths during the first wave of the epidemic and the number of second-wave cases. This could be because of both a sort of herd immunity and changes in behavioral response.

12 Nov 2020

Time to discuss potentially unpleasant side effects of COVID shots? Scientists say yes.

Drugmaker Pfizer is expected to seek federal permission to release its COVID-19 vaccine by the end of November, a move that holds promise for quelling the pandemic, but also sets up a tight time frame for making sure consumers understand what it will mean to actually get the shots.

12 Nov 2020

National study reveals incidents of avoidable harm in primary care

A national study* of general practices in England has revealed the frequency of incidents of significant avoidable harm in primary care, and also important new details.

12 Nov 2020

MD Anderson presents positive clinical data from combination cancer therapies at SITC 2020

Promising clinical results with combination treatments for patients with melanoma and lung cancer highlight immunotherapy advances being presented by researchers from The University of Texas MD Anderson Cancer Center at The Society for Immunotherapy of Cancer 35th Anniversary Annual Meeting & Pre-Conference Programs.

11 Nov 2020

Orange County struggles with health equity — and battles state restrictions

California's most popular amusement park has become the focal point of a struggle over how best to contain COVID-19 while keeping the economy afloat.

10 Nov 2020

Medical diagnoses of “diseases of despair” increase in Pennsylvania

Medical diagnoses involving alcohol-related disorders, substance-related disorders and suicidal thoughts and behaviors – commonly referred to as diseases of despair – increased in Pennsylvania health insurance claims between the years 2007 and 2018, according to researchers from Penn State Clinical and Translational Science Institute and Highmark Health Enterprise Analytics.

10 Nov 2020

Mask wearing, social distancing considerably reduce incidence of many diseases

Measures to reduce the spread of COVID-19 through non-pharmaceutical interventions (NPIs) such as mask wearing and social distancing are a key tool in combatting the impact of the ongoing coronavirus pandemic.

10 Nov 2020

Flu News and Research

SARS-CoV-2-specific IgM / IgG responses accurately predict COVID-19 outcome

Study shows limited influence of BMI on shaping SARS-CoV-2 antibody responses

Google searches for COVID-19 symptoms can anticipate case numbers

Xylitol and grapefruit seed extract nasal spray could help COVID-19 patients

Study sheds new light on the immune system response to COVID-19

Antiviral immune response is suppressed in COVID-19 patients compared to flu patients

Study explains why anti-inflammatory drugs benefit only few people with severe COVID-19

Researchers use aerosolized molecules to shut down proteins generated by coronavirus

PARP inhibitor, stenoparib inhibits pre- and post-entry processes of SARS-CoV-2 in vitro

Strategizing pediatric healthcare preparedness for the second wave of the COVID-19 pandemic

Drugs targeting neutrophils could reduce ARDS in severe COVID-19

MIT researchers unravel the molecular structure of key coronavirus protein

SARS-CoV-2-induces temporary loss of smell in mice

Modeling suggests lower COVID-19 cases in Lombardy's second wave

Time to discuss potentially unpleasant side effects of COVID shots? Scientists say yes.

National study reveals incidents of avoidable harm in primary care

MD Anderson presents positive clinical data from combination cancer therapies at SITC 2020

Orange County struggles with health equity — and battles state restrictions

Medical diagnoses of “diseases of despair” increase in Pennsylvania

Mask wearing, social distancing considerably reduce incidence of many diseases

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