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Omega-3 fatty acids can stimulate activation of brown and beige adipose tissues, study finds

Omega-3 fatty acids are able to stimulate the activation of brown and beige adipose tissues, a discovery that would promote the development of new therapies for obesity and other metabolism diseases, according to a research study published in the journal Nature Communications under the supervision of Professor Francesc Villarroya, from the Department of Biochemistry and Molecular Biomedicine and the Biomedical Research Center Red-Fisiopatología de la Obesidad y Nutrición (CIBEROBN) of the Institute of Health Carlos III.

21 Nov 2016

New review highlights challenges of studying resistance to antiangiogenic treatment in preclinical models

New blood vessel growth, or angiogenesis, is critical for cancer to grow and spread throughout the body.

21 Nov 2016

Scientists identify naturally occurring molecule that plays protective role in ALS

Researchers at the Virginia Tech Carilion Research Institute have identified a naturally occurring molecule that has the potential for preserving sites of communication between nerves and muscles in amyotrophic lateral sclerosis (ALS) and over the course of aging -- as well as a molecule that interferes with this helpful process.

18 Nov 2016

Allergan, Amgen submit BLA for ABP 215 oncology biosimilar medicine to FDA

Amgen and Allergan plc. today announced the submission of a Biologics License Application (BLA) to the U.S. Food and Drug Administration (FDA) for ABP 215, a biosimilar candidate to Avastin (bevacizumab).

16 Nov 2016

Experimental drug outperforms standard first-line therapy for advanced kidney cancer patients

An experimental kidney cancer drug outperformed the standard first-line therapy for patients with metastatic disease who are considered at risk for poorer than average outcomes, according to results of a randomized phase II clinical trial by researchers at Dana-Farber Cancer Institute.

15 Nov 2016

Promethera presents new preclinical NASH-Fibrosis data from HepaStem program at AASLD meeting

Promethera Biosciences SA, a world-leading cell therapy and regenerative medicine company targeting liver diseases, today announced the presentation of new preclinical NASH-Fibrosis data from its proprietary HepaStem program, demonstrating a beneficial effect of HepaStem in a nonalcoholic steatohepatitis (NASH) mouse model and confirming Hepastem’s unique and multifaceted mode of action.

15 Nov 2016

Research shows workings of biochemical pathway that helps control blood glucose

Research led by a Johns Hopkins University biologist demonstrates the workings of a biochemical pathway that helps control glucose in the bloodstream, a development that could potentially lead to treatments for diabetes.

14 Nov 2016

New guidelines provide recommendations on HER2 testing for patients with gastroesophageal cancers

The College of American Pathologists, the American Society for Clinical Pathology, and the American Society of Clinical Oncology today released an evidence-based clinical practice guideline on human epidermal growth factor receptor 2 (HER2) testing for patients with gastroesophageal cancers.

14 Nov 2016

New study identifies novel target for treatment of Graves' disease and other scarring eye conditions

A new class of therapies may be on the horizon for thyroid eye disease (TED) and other destructive scarring conditions.

11 Nov 2016

Scientists discover new mechanism responsible for regulation of glucose metabolism

Diabetes mellitus is a chronic disease that has become increasingly prevalent in the population: More than six million people are affected by the disease alone in Germany.

9 Nov 2016

Scientists find new way to bypass bowel cancer's defence against treatment

BLOCKING a molecule could bypass bowel cancer's defence against the drug cetuximab, according to new research presented at the National Cancer Research Institute Cancer Conference in Liverpool.

9 Nov 2016

TGen study identifies potential new drug targets to alleviate pain in pancreatic cancer patients

The Translational Genomics Research Institute has discovered potential drug targets to reduce pain in pancreatic cancer patients.

7 Nov 2016

Proteins in the blood of children can predict risk for incipient type 1 diabetes

Certain proteins in the blood of children can predict incipient type 1 diabetes, even before the first symptoms appear. A team of scientists at the Helmholtz Zentrum München, partners in the German Center for Diabetes Research, reported these findings in the 'Diabetologia' journal.

7 Nov 2016

New treatment with therapeutic short interfering RNA could help thwart cancer

In the fight against cancer, doctors dish out combination-blows of surgery, chemotherapy and other drugs to beat back a merciless foe. Now, scientists have taken early steps toward adding a stinging punch to clinicians' repertoire.

7 Nov 2016

UNC scientists find clue that may help explain why people differ in ability to survive arterial blockages

Researchers at the University of North Carolina School of Medicine have found a major clue that may explain why some people sustain relatively little damage from strokes or heart attacks despite severe arterial blockages.

7 Nov 2016

Researchers identify marker of aggressive disease for papillary thyroid cancer

A new discovery from University of Alberta scientists represents an important milestone in the fight against thyroid cancer. In a study published in EBioMedicine and recently presented at the American Thyroid Association annual meeting, the team has identified a marker of aggressive disease for papillary thyroid cancer, which comprises about 90 per cent of all thyroid cancers.

3 Nov 2016

High-protein diets may help prevent chronic diseases by reducing liver fat

According to a new nutritional study conducted by the German Institute of Human Nutrition on individuals with type 2 diabetes, high-protein diets reduced liver fat by up to 48 percent within six weeks. It did not matter whether the diet was mainly based on plant or animal protein.

2 Nov 2016

Heart problems from common cancer treatment can be alleviated by using gene therapy

Researchers of the Wihuri Research Institute and the University of Helsinki, Finland, have found that some of the harmful effects of a commonly used cancer drug can be alleviated by using gene therapy that stimulates blood vessel growth in the heart.

31 Oct 2016

Researchers find link between estrogen levels in lung tissue and SMLA in postmenopausal women

Thanks to advances in medical imaging, the detection rate for synchronous multiple lung adenocarcinoma (SMLA) has been on the rise. Cases of SMLA in Japanese women have been on the rise despite having a national smoking rate of less than 10% in recent years.

26 Oct 2016

New scaffold could improve outcome of periodontal regenerative surgery

A new regenerative scaffold made of biosafe collagen hydrogel and collagensponge could possess the ability of retaining fibroblastic growth factor-2 (FGF2) and stimulate the periodontal tissue regeneration, according to new research published in The Open Dentistry Journal.

24 Oct 2016

Growth Factor News and Research

Omega-3 fatty acids can stimulate activation of brown and beige adipose tissues, study finds

New review highlights challenges of studying resistance to antiangiogenic treatment in preclinical models

Scientists identify naturally occurring molecule that plays protective role in ALS

Allergan, Amgen submit BLA for ABP 215 oncology biosimilar medicine to FDA

Experimental drug outperforms standard first-line therapy for advanced kidney cancer patients

Promethera presents new preclinical NASH-Fibrosis data from HepaStem program at AASLD meeting

Research shows workings of biochemical pathway that helps control blood glucose

New guidelines provide recommendations on HER2 testing for patients with gastroesophageal cancers

New study identifies novel target for treatment of Graves' disease and other scarring eye conditions

Scientists discover new mechanism responsible for regulation of glucose metabolism

Scientists find new way to bypass bowel cancer's defence against treatment

TGen study identifies potential new drug targets to alleviate pain in pancreatic cancer patients

Proteins in the blood of children can predict risk for incipient type 1 diabetes

New treatment with therapeutic short interfering RNA could help thwart cancer

UNC scientists find clue that may help explain why people differ in ability to survive arterial blockages

Researchers identify marker of aggressive disease for papillary thyroid cancer

High-protein diets may help prevent chronic diseases by reducing liver fat

Heart problems from common cancer treatment can be alleviated by using gene therapy

Researchers find link between estrogen levels in lung tissue and SMLA in postmenopausal women

New scaffold could improve outcome of periodontal regenerative surgery

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