Heart Attack (Myocardial Infarction) News and Research

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A Heart Attack (Myocardial Infarction) occurs when blood flow to a section of heart muscle becomes blocked. If the flow of blood isn’t restored quickly, the section of heart muscle becomes damaged from lack of oxygen and begins to die.

Heart attack is a leading killer of both men and women in the United States. But fortunately, today there are excellent treatments for heart attack that can save lives and prevent disabilities. Treatment is most effective when started within 1 hour of the beginning of symptoms. Heart attacks occur most often as a result of a condition called coronary artery disease (CAD). In CAD, a fatty material called plaque (plak) builds up over many years on the inside walls of the coronary arteries (the arteries that supply blood and oxygen to your heart). Eventually, an area of plaque can rupture, causing a blood clot to form on the surface of the plaque. If the clot becomes large enough, it can mostly or completely block the flow of oxygen-rich blood to the part of the heart muscle fed by the artery.

Adult, or post-natal, stem cells have the same ability as embryonic stem cells to multiply

In a ground-breaking study, scientists at Children's Hospital of Pittsburgh have discovered that adult, or post-natal, stem cells have the same ability as embryonic stem cells to multiply, a previously unknown characteristic indicating that post-natal stem cells may play an important therapeutic role.

27 Jun 2005

Scientists have discovered how C-reactive protein is able to access endothelial cells

For the first time, scientists have discovered how C-reactive protein, or CRP, is able to access endothelial cells. The UC Davis researchers' findings will be published in the July issue of Arteriosclerosis, Thrombosis, and Vascular Biology, one of the American Heart Association's leading journals.

27 Jun 2005

Adult, or post-natal, stem cells have the same ability as embryonic stem cells to multiply

27 Jun 2005

Determining prognosis in patients with chest pain now easier and more accurate

A new, more precise test is available to improve the accuracy of detecting coronary artery disease and risk of heart attack, and can be done right at the bedside.

22 Jun 2005

Should everyone over 50 be taking aspirin?

Experts go head to head in this week’s BMJ over whether everyone over 50 should take a daily aspirin to reduce their risk of heart attacks and strokes.

16 Jun 2005

Schiavo finally laid to rest

Hopefully autopsy findings released today will finally allow Terri Schiavo to be laid to rest.

16 Jun 2005

Acute coronary syndrome patients at increased risk of stroke

Patients hospitalized with chest pain or heart attack symptoms are at an increased risk of stroke even after being discharged, according to a study published in Circulation: Journal of the American Heart Association.

15 Jun 2005

Two common gene variations are associated with the risk for developing chronic kidney disease

Two common gene variations are associated with the risk for developing chronic kidney disease, according to a study by researchers at the Johns Hopkins Bloomberg School of Public Health and other institutions. One variant increases risk and the other decreases risk with a similar effect in whites, African-Americans, diabetic and non-diabetic individuals.

14 Jun 2005

Invasive treatment including stenting may be more effective for heart attack patients who arrive late at hospital

Invasive treatment including stenting may have better outcomes than conventional treatments for heart attack patients who arrive at the hospital more than 12 hours after symptoms began, according to a study in the June 15 issue of JAMA.

14 Jun 2005

Fish oil does not lower risk of serious heart rhythm abnormalities for patients with implantable defibrillators

Even though previous research has shown that fatty acids from fish oil reduce the risk of sudden cardiac death, patients with implantable defibrillators who took fish oil supplements did not see a reduction in serious heart rhythm abnormalities, according to a study in the June 15 issue of JAMA: The Journal of the American Medical Association.

14 Jun 2005

New study supporting the importance of aggressive cholesterol-lowering

New clinical data shows that intensive cholesterol-lowering to targets below currently recommended levels significantly reduces the risk of heart attack and stroke for people with diabetes and heart disease.

14 Jun 2005

Teen-age boys with type 1 diabetes showed evidence of greater atherosclerosis

Youths with type 1 diabetes, especially boys, already show early signs of cardiovascular disease by their teen-age years, according to researchers from the Keck School of Medicine of the University of Southern California and Childrens Hospital Los Angeles.

13 Jun 2005

Tight glucose control lowers CVD by about 50 percent in diabetes

A significantly lower risk of heart disease can now be added to the list of proven long-term benefits of tight glucose control in people with type 1 diabetes.

12 Jun 2005

Rimonabant study shows significant improvements in HbA1c and cardiometabolic risk factors in people with type 2 diabetes

The reported results of a one-year phase III study in 1045 people with type 2 diabetes treated with rimonabant, the first in a new class of therapeutic agents called selective CB1 Blockers, were that rimonabant 20 mg significantly improved HbA1c (a measure of blood sugar control), dyslipidemia (abnormal levels of fat in the blood), and systolic blood pressure with a concomitant substantial reduction in abdominal obesity in people with type 2 diabetes treated with oral anti-diabetic medications and requiring further control.

12 Jun 2005

Genetic variations predispose Mexican Americans to insulin resistance

Although numerous studies have shown that low-grade inflammation is linked to heart disease and diabetes, more recent studies have shown that inflammation plays a role in insulin resistance, a syndrome that leads to diabetes and heart disease and affects about one in four adults in the United States.

12 Jun 2005

Over-the-counter painkillers more likely to cause heart attacks than banned drug Vioxx

Researchers in the UK are saying that some of the most commonly used painkillers are more likely to cause heart attacks than Vioxx, the arthritis drug withdrawn from the market last year after it was linked to heart disease.

12 Jun 2005

Ibruprofen and other commonly used painkillers for treating inflammation may increase the risk of heart attack

Patients should not stop taking the drugs involved - non-steroidal anti-inflammatory drugs (NSAIDS) - but further investigation into these treatments is needed, say the authors.

10 Jun 2005

Commonly used painkillers for treating inflammation may increase the risk of heart attack

Patients should not stop taking the drugs involved - non-steroidal anti-inflammatory drugs (NSAIDS) - but further investigation into these treatments is needed, say the authors.

9 Jun 2005

New start-up to market test that predicts heart attack risk

PrognostiX, a start-up company based on Cleveland Clinic technology, has received approval from the U.S. Food and Drug Administration to begin selling a diagnostic test capable of identifying patients who are in imminent danger of heart attack or death.

9 Jun 2005

Arena Pharmaceuticals issued new patent

Arena Pharmaceuticals has announced that it was issued U.S. patent number 6,902,902, entitled "Human G Protein-Coupled Receptors and Modulators Thereof for the Treatment of Metabolic-Related Disorders," by the U.S. Patent Office.

8 Jun 2005

Heart Attack (Myocardial Infarction) News and Research

Further Reading

Adult, or post-natal, stem cells have the same ability as embryonic stem cells to multiply

Scientists have discovered how C-reactive protein is able to access endothelial cells

Adult, or post-natal, stem cells have the same ability as embryonic stem cells to multiply

Determining prognosis in patients with chest pain now easier and more accurate

Should everyone over 50 be taking aspirin?

Schiavo finally laid to rest

Acute coronary syndrome patients at increased risk of stroke

Two common gene variations are associated with the risk for developing chronic kidney disease

Invasive treatment including stenting may be more effective for heart attack patients who arrive late at hospital

Fish oil does not lower risk of serious heart rhythm abnormalities for patients with implantable defibrillators

New study supporting the importance of aggressive cholesterol-lowering

Teen-age boys with type 1 diabetes showed evidence of greater atherosclerosis

Tight glucose control lowers CVD by about 50 percent in diabetes

Rimonabant study shows significant improvements in HbA1c and cardiometabolic risk factors in people with type 2 diabetes

Genetic variations predispose Mexican Americans to insulin resistance

Over-the-counter painkillers more likely to cause heart attacks than banned drug Vioxx

Ibruprofen and other commonly used painkillers for treating inflammation may increase the risk of heart attack

Commonly used painkillers for treating inflammation may increase the risk of heart attack

New start-up to market test that predicts heart attack risk

Arena Pharmaceuticals issued new patent

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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