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Hormonal steroids found to boost drug resistance in gonorrhea bacteria

Study uncovers how Neisseria gonorrhoeae, a major sexually transmitted infection pathogen, utilizes host-produced hormonal steroids to enhance its drug resistance and survival, revealing a complex interaction between bacterial resistance mechanisms and human hormonal environment.

13 Feb 2024

Combined approach needed to address oral health inequalities and systemic health burden

'Time to put your money where your mouth is: addressing inequalities in oral health' is the new Economist Impact white paper published today, commissioned by the EFP (European Federation of Periodontology) with support from Haleon.

13 Feb 2024

Study shows ritonavir-boosted nirmatrelvir remains effective against new omicron variants in the U.S

The effectiveness of ritonavir-boosted nirmatrelvir (NMV-r) against Omicron variants.

13 Feb 2024

Smoking, drinking, and dietary habits linked to head and neck cancer risk, study finds

Study in JAMA Otolaryngology-Head & Neck Surgery examines the link between smoking, drinking, and dietary habits and the risk of developing head and neck cancer (HNC), highlighting the significant impact of lifestyle choices on cancer risk.

12 Feb 2024

Oral azithromycin reduces maternal sepsis and healthcare costs in low-resource settings

Sepsis, a severe infection that can lead to tissue damage, organ failure, and death, is one of the top three causes of maternal deaths worldwide, according to the World Health Organization.

12 Feb 2024

Study uncovers missing piece in the complex nerve-network needed for left-right turns

Have you ever wondered what happens in the brain when we move to the right or left? Most people don't; they just do it without thinking about it. But this simple movement is actually controlled by a complex process.

12 Feb 2024

Drug repurposing study finds lonafarnib effective against RSV

A study in Nature Communications identifies lonafarnib from the ReFRAME drug-repurposing library as a potent inhibitor of the RSV fusion protein, showing promise in reducing RSV infection in vitro and in vivo.

11 Feb 2024

New study finds 4’-fluorouridine effective against avian influenza in vitro and in vivo

A PLOS Pathogens study reveals 4’-fluorouridine effectively combats avian influenza in vitro and in animal models, showing promise as a treatment that overcomes resistance and reduces disease severity without significant adverse effects.

11 Feb 2024

UT Health San Antonio School of Dentistry opens special-care dental clinic in South Texas

The UT Health San Antonio School of Dentistry has opened a special-care dental clinic, the first of its kind in an academic setting in South Texas that will serve people of all ages with intellectual, developmental, cognitive or physical disabilities.

9 Feb 2024

CARB-X awards $1.8 million to Visby Medical to develop a portable rapid PCR test for gonorrhea

Combating Antibiotic-Resistant Bacteria Biopharmaceutical Accelerator (CARB-X) will award up to US$1.8 million to biotechnology company, Visby Medical, to develop a portable rapid polymerase chain reaction (PCR) diagnostic to detect the presence of the pathogen that causes gonorrhea, Neisseria gonorrhoeae (NG), and its susceptibility to ciprofloxacin, a former frontline oral antibiotic that can no longer treat resistant NG.

9 Feb 2024

Stapokibart shows promise in reducing nasal congestion in seasonal allergy patients, study finds

The efficacy and safety of stapokibart as an in patients with seasonal allergic rhinitis (SAR).

9 Feb 2024

Selective androgen receptor modulator has anti-tumor effects in ER-positive breast cancer patients

A research paper published today (8 February 2024) in The Lancet Oncology demonstrates that the drug enobosarm, a selective androgen receptor modulator which stimulates the male sex hormone receptor has anti-tumour effects in estrogen receptor positive breast cancer patients.

8 Feb 2024

Hormonal steroids could make gonorrhea untreatable

You know that package warning that oral birth control won't prevent STIs? Well in the case of gonorrhea, the sexually transmitted bacterium that causes the disease can use those hormones to help it resist antibiotic attacks.

8 Feb 2024

Healthcare providers' assumptions about parents' preferences hinder effective care for child diarrhea

Young children in India who suffer from life-threatening diarrhea frequently are given ineffective treatments because health providers misperceive the wishes of a child's caregiver, according to a novel new study.

8 Feb 2024

New study links legume consumption to lower risk of colorectal cancer

Researchers collated and analyzed 12 studies comprising more than 17 years’ worth of case-control experiments aimed at elucidating site-specific cancer outcomes of legume consumption.

8 Feb 2024

Chewing tobacco linked to higher stroke and cancer risk, study finds

Chewing tobacco significantly increases the risk of strokes and several types of cancer, revealing critical health implications for its 270 million global users.

7 Feb 2024

Study shines light on partial endothelial-to-mesenchymal transition in the tumor microenvironment

Endothelial-mesenchymal transition (EndoMT, also termed as EndMT), a biological process resulting in the formation of mesenchymal (or lineage-committed) phenotypes from endothelial cells (lining blood vessels), plays a crucial role in tumor progression.

7 Feb 2024

Quest Pharm and Aston University develop world-first tablet to treat mouth ulcerations in chemotherapy patients

A Knowledge Transfer Partnership (KTP) between UK pharmaceutical company Quest Pharm and Aston University has developed a world-first tablet to treat the serious mouth ulcerations caused by high-dose chemotherapy.

7 Feb 2024

What natural compounds can help you manage your rosacea?

Researchers reviewed existing data on rosacea management using botanicals.

7 Feb 2024

Promising influenza drug candidate shows activity against resistant variants

Influenza A viruses with induced resistance to a new candidate antiviral drug were found to be impaired in cell culture and weakened in animals, according to a study by researchers in the Center for Translational Antiviral Research at Georgia State University.

6 Feb 2024

Oral News and Research

Hormonal steroids found to boost drug resistance in gonorrhea bacteria

Combined approach needed to address oral health inequalities and systemic health burden

Study shows ritonavir-boosted nirmatrelvir remains effective against new omicron variants in the U.S

Smoking, drinking, and dietary habits linked to head and neck cancer risk, study finds

Oral azithromycin reduces maternal sepsis and healthcare costs in low-resource settings

Study uncovers missing piece in the complex nerve-network needed for left-right turns

Drug repurposing study finds lonafarnib effective against RSV

New study finds 4’-fluorouridine effective against avian influenza in vitro and in vivo

UT Health San Antonio School of Dentistry opens special-care dental clinic in South Texas

CARB-X awards $1.8 million to Visby Medical to develop a portable rapid PCR test for gonorrhea

Stapokibart shows promise in reducing nasal congestion in seasonal allergy patients, study finds

Selective androgen receptor modulator has anti-tumor effects in ER-positive breast cancer patients

Hormonal steroids could make gonorrhea untreatable

Healthcare providers' assumptions about parents' preferences hinder effective care for child diarrhea

New study links legume consumption to lower risk of colorectal cancer

Chewing tobacco linked to higher stroke and cancer risk, study finds

Study shines light on partial endothelial-to-mesenchymal transition in the tumor microenvironment

Quest Pharm and Aston University develop world-first tablet to treat mouth ulcerations in chemotherapy patients

What natural compounds can help you manage your rosacea?

Promising influenza drug candidate shows activity against resistant variants

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How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

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