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Latona acquires patent rights and orphan drug status to drug compound for rheumatoid arthritis

Latona Life Sciences Inc. announced today that it has entered into two agreements for the acquisition of patent rights and orphan drug status to a novel late-stage drug, trademarked "Oralgam," for the treatment of Juvenile and Adult Rheumatoid Arthritis.

24 Apr 2008

MacroChem acquires Virium Pharmaceuticals

MacroChem Corporation announced today that on April 18, 2008 it acquired Virium Pharmaceuticals Inc., a non-public, development stage company developing and commercializing novel therapeutics, with a portfolio of clinical stage product candidates focused in oncology, including its next generation nucleoside analogue licensed from the Southern Research Institute.

23 Apr 2008

StemCells, Inc. granted U.S. patent covering composition of neural stem cells derived from any tissue source

StemCells, Inc. announced today that the U.S. Patent and Trademark Office has issued U.S. Patent Number 7,361,505 with broad claims covering human neural stem cells derived from any tissue source, including embryonic, fetal, juvenile, or adult tissue. The ‘505 patent is exclusively licensed to StemCells.

23 Apr 2008

Lorus initiates development program exploring novel route of administration for LOR-2040

Lorus Therapeutics Inc. today announced the start of a development program aimed at expanding the therapeutic application of its lead clinical-stage drug LOR-2040 for the treatment of superficial bladder cancer.

22 Apr 2008

Researchers describe key molecule responsible for the immature state of the tumor vasculature

Immune therapies are considered very promising in cancer medicine: Tumor-fighting immune cells are supposed to invade tumor tissue and eliminate cancer cells right there. Although this works well in the test tube, clinical application often fails because immune cells are unable to get into the tumor tissue from the bloodstream in sufficient numbers.

21 Apr 2008

Discovery of method for clamping down on a cancer-promoting enzyme

There are many pathways that allow an errant gene to turn a cell cancerous, and a number of these pathways go through a single enzyme called the p21-activated kinase 1, or PAK1.

18 Apr 2008

Purdue's new vaccine under development may provide protection against highly pathogenic bird flu

A new vaccine under development may provide protection against highly pathogenic bird flu and its evolving forms, according to researchers at Purdue University and the Centers for Disease Control and Prevention who discovered the new preventative drug and have tested it in mice.

17 Apr 2008

Module map links embryonic stem cells and cancer stem cells

A new study suggests that a genetic fingerprint associated with normal embryonic stem cells may be important for the development and function of cancer stem cells.

10 Apr 2008

Too many gene copies stimulate tumor cell growth

New data, generated by Peter Lichter and colleagues, at the German Cancer Research Center, Heidelberg, have characterized a molecular pathway underlying low-grade forms of a type of brain tumor known as an astrocytoma.

9 Apr 2008

Rreishi mushroom and green tea for cancer prevention

Both the reishi mushroom (Ganoderma lucidum; Lingzhi) and green tea have long held a place in traditional medicine in China and other Asian countries, for the general promotion of health and long life and for the treatment of specific diseases.

9 Apr 2008

Angina drug ranolazine potentially useful against heart rhythm disorders

A recently approved angina drug may also represent a powerful new treatment for a rare hereditary syndrome that places teens at risk for sudden cardiac death, according to research presented on April 1st at the 57th Annual Scientific Sessions of the American College of Cardiology (ACC) in Chicago.

9 Apr 2008

NanoViricides begins HIV drug animal trials

NanoViricides, Inc. has announced that preliminary animal trials of the Company's HIV therapeutic candidates have begun at a BioSafety Level 3 (BSL-3) Laboratory facility in Boston, MA.

8 Apr 2008

Scientists visualize the machinery of mRNA splicing

Recent research at Yale provided a glimpse of the ancient mechanism that helped diversify our genomes; it illuminated a relationship between gene processing in humans and the most primitive organisms by creating the first crystal structure of a crucial self-splicing region of RNA.

7 Apr 2008

Roswell Park Cancer Institute awarded three-years funding for ovarian cancer vaccine

The Ovarian Cancer Research Fund has awarded a $900,000 research grant to Kunle Odunsi, MD, Department of Gynecologic Oncology, and his colleagues at Roswell Park Cancer Institute (RPCI) to collaborate on developing a promising vaccine to unleash the power of the immune system against cancer.

7 Apr 2008

New research in monkeys may lead to new strategy for treating cocaine addiction

New research in monkeys suggests the feasibility of treating cocaine addiction with a "replacement" drug that mimics the effects of cocaine but has less potential for abuse - similar to the way nicotine and heroin addictions are treated.

7 Apr 2008

Mitochondria play role in pathogenesis of AD and estrogen-induced neuroprotection

As the major source of free radicals in cells, mitochondria contribute to the high levels of oxidative stress believed to play a role in the pathogenesis of Alzheimer's disease.

7 Apr 2008

Animal research shows potential of amphetamine-like drug for treating cocaine addiction

7 Apr 2008

Light-powered nanomachine kills cancer cells

Researchers from the Nano Machine Center at the California NanoSystems Institute at UCLA have developed a novel type of nanomachine that can capture and store anticancer drugs inside tiny pores and release them into cancer cells in response to light.

2 Apr 2008

Scientists discover how polyketides form their ringlike shape

Many top-selling drugs used to treat cancer and lower cholesterol are made from organic compounds called polyketides, which are found in nature but historically difficult for chemists to alter and reproduce in large quantities.

2 Apr 2008

New genetic clues to diabetes

An international team that included scientists from the National Human Genome Research Institute (NHGRI), part of the National Institutes of Health (NIH), today reported it has identified six more genetic variants involved in type 2 diabetes, boosting to 16 the total number of genetic risk factors associated with increased risk of the disease.

1 Apr 2008

Therapeutics News and Research

Latona acquires patent rights and orphan drug status to drug compound for rheumatoid arthritis

MacroChem acquires Virium Pharmaceuticals

StemCells, Inc. granted U.S. patent covering composition of neural stem cells derived from any tissue source

Lorus initiates development program exploring novel route of administration for LOR-2040

Researchers describe key molecule responsible for the immature state of the tumor vasculature

Discovery of method for clamping down on a cancer-promoting enzyme

Purdue's new vaccine under development may provide protection against highly pathogenic bird flu

Module map links embryonic stem cells and cancer stem cells

Too many gene copies stimulate tumor cell growth

Rreishi mushroom and green tea for cancer prevention

Angina drug ranolazine potentially useful against heart rhythm disorders

NanoViricides begins HIV drug animal trials

Scientists visualize the machinery of mRNA splicing

Roswell Park Cancer Institute awarded three-years funding for ovarian cancer vaccine

New research in monkeys may lead to new strategy for treating cocaine addiction

Mitochondria play role in pathogenesis of AD and estrogen-induced neuroprotection

Animal research shows potential of amphetamine-like drug for treating cocaine addiction

Light-powered nanomachine kills cancer cells

Scientists discover how polyketides form their ringlike shape

New genetic clues to diabetes

Next-generation therapeutics eBook eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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