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Bacteria barge inside guard cells and initiate a powerful immune response

Immune cells that are the body's front-line defense don't necessarily rest quietly until invading bacteria lock onto receptors on their outside skins and rouse them to action, as previously thought.

18 Apr 2007

Taking a jab at cancer by stimulating the immune system

As the first FDA-approved cancer vaccine, designed to protect against human papillomavirus, has moved from scientific discussion to social debate, other vaccine studies are continuing to make progress.

18 Apr 2007

Avalon Pharmaceuticals announces results of AVN944 biomarker study

Avalon Pharmaceuticals has announced the results of an AVN944 biomarker study that utilized Avalon's proprietary AvalonRx technology to identify gene signatures that may be useful for patient stratification.

18 Apr 2007

Anadys Pharmaceuticals presents data showing ANA773 promotes anti-tumor activity of killer cells

Anadys Pharmaceuticals presented data from an in vitro study showing that the active metabolite of ANA773 promotes natural killer (NK) cell-mediated anti-tumor response by inducing cytokine secretion, cytolysis of tumor cells and enhanced antibody-dependent cellular cytotoxicity (ADCC), during a poster presentation at the Annual Meeting of the American Association of Cancer Research (AACR) in Los Angeles.

18 Apr 2007

Biomira selects PX-866 as clinical development candidate

Biomira Inc. has announced that it has selected PX-866 as its next clinical development candidate.

17 Apr 2007

Snake venom toxin as a treatment for prostate cancer

This certainly sounds unusual, but Dr. Son and colleagues report on the effectiveness of the snake venom toxin (SVT) Vipera lebetina turanica in the inhibition of androgen-independent prostate cancer (AICAP) in the February 2007 issue of Molecular Cancer Therapeutics .

16 Apr 2007

New diagnostic technologies to predict and monitor cancer risks

Molecular messages and signals circulating in blood or contained in cells lining the airway can identify early stage cancer, according to research reported at the 2007 Annual Meeting of the American Association for Cancer Research.

16 Apr 2007

Lactate instead of glucose after traumatic brain injury

The chemical lactate has gotten a bad rap. Conventional wisdom considered it to be little more than the bane of runners and other athletes, causing stiff muscles and fatigue, and the "sour" in sour milk. It turns out that view may have been too narrow.

15 Apr 2007

Ranbaxy receives U.S. approval to market Loratadine Antihistamine tablets

Ohm Laboratories, a wholly owned subsidiary of Ranbaxy Laboratories Limited, has announced that Ranbaxy has received approval from the U. S. Food and Drug Administration to manufacture and commercialize its Loratadine Orally Disintegrating Tablets, 10mg. The antihistamine previously made the switch from the prescription to the OTC market.

15 Apr 2007

Laser technique to identify deadly anthrax

Texas A&M University and Princeton University physicists have joined forces to perfect a powerful new weapon in the war on terrorism – a laser technique to identify deadly anthrax spores.

15 Apr 2007

Link between immune system and high plasma lipid levels

Researchers at the University of Chicago have found an unsuspected link between the immune system and high plasma lipid levels (cholesterol and triglycerides in the blood) in mice.

15 Apr 2007

Cytokinetics initiates of phase II clinical trial for CK-1827452

Cytokinetics has announced the initiation of a Phase II clinical trials program evaluating CK-1827452, a novel cardiac myosin activator for the potential treatment of patients with either acutely decompensated or chronic heart failure.

15 Apr 2007

Bacteria can barge inside immune cells

Immune cells that are the body's front-line defense don't necessarily rest quietly until invading bacteria lock onto receptors on their outside skins and rouse them to action, as previously thought. In a new paper, University of Michigan scientists describe their findings that bacteria can barge inside these guard cells and independently initiate a powerful immune response.

14 Apr 2007

Three proteins could be new targets for treating stroke, brain and spinal cord injuries

Some mature brain cells can grow new extensions when the amount of three particular proteins on their surface increases, a new study shows.

12 Apr 2007

Breakthrough in photoswitchable fluorescent protein science

University of Oregon scientists have identified molecular features that determine the light-emitting ability green fluorescent proteins, and by strategically inserting a single oxygen atom they were able to keep the lights turned off for up to 65 hours.

11 Apr 2007

Pharmacopeia announces positive results in hypertension and diabetic nephropathy trial

Pharmacopeia ( NASDAQ:PCOP ) , an innovator in the discovery and development of novel small molecule therapeutics, today announced positive results from the initial Phase 1 clinical trial of PS433540, the company's lead internal product candidate for the treatment of hypertension and diabetic nephropathy.

11 Apr 2007