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DNA, or deoxyribonucleic acid, is the hereditary material in humans and almost all other organisms. Nearly every cell in a person’s body has the same DNA. Most DNA is located in the cell nucleus (where it is called nuclear DNA), but a small amount of DNA can also be found in the mitochondria (where it is called mitochondrial DNA or mtDNA).

Oxygen-rich postnatal atmosphere results in cell cycle arrest of cardiomyocytes

Scientific research at UT Southwestern Medical Center previously discovered that the newborn animal heart can heal itself completely, whereas the adult heart lacks this ability. New research by the same team today has revealed why the heart loses its incredible regenerative capability in adulthood, and the answer is quite simple - oxygen.

25 Apr 2014

Research findings can impact lives of people with autism today

A new study from investigators with the Autism Genome Project, the world's largest research project on identifying genes associated with risk for autism, has found that the comprehensive use of copy number variant (CNV) genetic testing offers an important tool in individualized diagnosis and treatment of autism.

25 Apr 2014

Measuring tumors' oxygen levels could help doctors make decisions about treatments

Unlike healthy cells, cancer cells thrive when deprived of oxygen. Tumors in low-oxygen environments tend to be more resistant to therapy and spread more aggressively to other parts of the body.

25 Apr 2014

Studies report new genetic disorder associated with degeneration of central/peripheral nervous systems

A newly identified genetic disorder associated with degeneration of the central and peripheral nervous systems in humans, along with the genetic cause, is reported in the April 24, 2014 issue of Cell.

25 Apr 2014

Roche's cobas HPV Test gets FDA approval for first-line primary screening for cervical cancer

Roche announced today that the U.S. Food and Drug Administration approved the cobas HPV (Human Papillomavirus) Test for use as a first-line primary screening test for cervical cancer in women 25 and older. The approval follows the March 12 unanimous recommendation from the Microbiology Devices Panel of the FDA's Medical Devices Advisory Committee, making the cobas HPV Test the first and only HPV test in the United States approved for first-line primary screening.

From Roche Sequencing and Life Science 25 Apr 2014

91% of Americans know genetic information has important utility in managing health

23andMe, the leading personal genetics company, is celebrating National DNA Day by taking an in-depth look at what Americans know about their DNA and how genetics play a role in our everyday lives. The survey found that 91 percent of Americans know that their genetic information has important utility in managing their health.

23 Apr 2014

Personalis receives CAP accreditation

Personalis, Inc., a leading provider of genome-based diagnostics, announced today that its onsite clinical laboratory has received accreditation from the College of American Pathologists (CAP), meeting the highest standard of excellence in clinical laboratory practices.

23 Apr 2014

Scientists develop DNA nanodevices that survive body's immune defenses

It's a familiar trope in science fiction: In enemy territory, activate your cloaking device. And real-world viruses use similar tactics to make themselves invisible to the immune system.

23 Apr 2014

Research shows epigenetic changes contributed to human survival over other extinct species

In parallel with modern man (Homo sapiens), there were other, extinct types of humans with whom we lived side by side, such as Neanderthals and the recently discovered Denisovans of Siberia. Yet only Homo sapiens survived. What was it in our genetic makeup that gave us the advantage?

23 Apr 2014

Study: Added benefit of turoctocog alfa is not proven

Turoctocog alfa (trade name: NovoEight) has been approved since November 2013 for the prevention and treatment of bleeding in patients with haemophilia A.

23 Apr 2014

OGT releases new application note detailing performance of two DNA labelling kits

Oxford Gene Technology, The Molecular Genetics Company, has released a new application note detailing the technical evaluation of two DNA labelling kits, where OGT’s CytoSure Genomic DNA Labelling Kits were found to be quicker and more accurate than a leading alternative.

From Oxford Gene Technology 23 Apr 2014

New computational tool identifies undiagnosed illnesses and unknown gene mutations

23 Apr 2014

University of Utah software successfully identifies diseases with unknown gene mutations in three separate cases

A computational tool developed at the University of Utah (U of U) has successfully identified diseases with unknown gene mutations in three separate cases, U of U researchers and their colleagues report in a new study in The American Journal of Human Genetics. The software, Phevor (Phenotype Driven Variant Ontological Re-ranking tool), identifies undiagnosed illnesses and unknown gene mutations by analyzing the exomes, or areas of DNA where proteins that code for genes are made, in individual patients and small families.

22 Apr 2014

OncoSec to present update of data from Phase 2 melanoma study at ASCO Annual Meeting

OncoSec Medical Inc., a company developing its ImmunoPulse DNA-based immunotherapy to treat solid tumors, will present an update of data from their Phase 2 melanoma study at the American Society of Clinical Oncology's 50th Annual Meeting, taking place May 30-June 3, 2014, at McCormick Place in Chicago, Illinois.

22 Apr 2014

Interleukin receives conditional approval to offer results of PerioPredict genetic risk test

Interleukin Genetics, Inc. today announced it has received conditional approval from the New York State Department of Health to offer, process and report the results of the PerioPredict™ Genetic Risk Test for periodontal disease.

22 Apr 2014

Study explains biological processes of malignant cancer cells

Cancer cells may be known for their uncontrollable growth and spread, but they also differ from normal tissue in another manner: how they produce energy.

22 Apr 2014

Researcher explores public perceptions related to newborn screening programs

While 94 per cent of Canadians surveyed said they would participate in public health programs that screen newborns for a specific number of genetic conditions, only 80 per cent said they would be willing to participate in screening that would sequence their newborns' genomes.

22 Apr 2014

SIRT1 protein necessary for telomere elongation and genome integrity during cell reprogramming

Cell reprogramming converts specialised cells such as nerve cells or skin cells towards an embryonic stem cell state. This reversal in the evolutionary development of cells also requires a reversal in the biology of telomeres, the structures that protect the ends of chromosomes; whilst under normal conditions telomeres shorten over time, during cell reprogramming they follow the opposite strategy and increase in length.

22 Apr 2014

Researchers study evolution of harmful organisms from 1 bacterial family

For the first time, researchers have studied the Black Death bacterium's entire family tree to fully understand how some of the family members evolve to become harmful.

22 Apr 2014

Small gene embedded in large gene contributes to development of acute myeloid leukemia

A small gene that is embedded in a larger, well-known gene is the true leukemia-promoting force usually attributed to the larger gene, according to a new study by researchers at The Ohio State University Comprehensive Cancer Center - Arthur G. James Cancer Hospital and Richard J. Solove Research Institute (OSUCCC - James).

22 Apr 2014

DNA News and Research

Further Reading

Oxygen-rich postnatal atmosphere results in cell cycle arrest of cardiomyocytes

Research findings can impact lives of people with autism today

Measuring tumors' oxygen levels could help doctors make decisions about treatments

Studies report new genetic disorder associated with degeneration of central/peripheral nervous systems

Roche's cobas HPV Test gets FDA approval for first-line primary screening for cervical cancer

91% of Americans know genetic information has important utility in managing health

Personalis receives CAP accreditation

Scientists develop DNA nanodevices that survive body's immune defenses

Research shows epigenetic changes contributed to human survival over other extinct species

Study: Added benefit of turoctocog alfa is not proven

OGT releases new application note detailing performance of two DNA labelling kits

New computational tool identifies undiagnosed illnesses and unknown gene mutations

University of Utah software successfully identifies diseases with unknown gene mutations in three separate cases

OncoSec to present update of data from Phase 2 melanoma study at ASCO Annual Meeting

Interleukin receives conditional approval to offer results of PerioPredict genetic risk test

Study explains biological processes of malignant cancer cells

Researcher explores public perceptions related to newborn screening programs

SIRT1 protein necessary for telomere elongation and genome integrity during cell reprogramming

Researchers study evolution of harmful organisms from 1 bacterial family

Small gene embedded in large gene contributes to development of acute myeloid leukemia

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