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USAID blog reports on India's Call to Action Summit for Child Survival, Development

In a post in USAID's "IMPACTblog," Ariel Pablos-Mendez, assistant administrator for global health at USAID, provides an overview of India's "Call to Action Summit for Child Survival and Development," which took place last week, writing, "Led by India's Ministry of Health and Family Welfare, the Summit called for an accelerated response to decrease child mortality across the country."

14 Feb 2013

Link between Jagged-1 protein and bone formation

Researchers from the University of Pennsylvania School of Veterinary Medicine have discovered that a protein called Jagged-1 stimulates human stem cells to differentiate into bone-producing cells.

14 Feb 2013

President Obama delivers SOTU address, mentioning trade agreements, AIDS-free generation

"President Barack Obama outlined an ambitious agenda in his State of the Union address Tuesday that included raising the minimum wage, increasing spending on infrastructure, attacking climate change and passing gun-control legislation," the Wall Street Journal reports.

14 Feb 2013

CELF6 genetic mutation may underlie common behaviors seen in people with autism

Scientists at Washington University School of Medicine in St. Louis have identified a genetic mutation that may underlie common behaviors seen in some people with autism, such as difficulty communicating and resistance to change.

14 Feb 2013

Targacept reports net loss of $15.9 million for fourth quarter 2012

Targacept, Inc., a clinical-stage biopharmaceutical company developing novel NNR Therapeutics, today reported its financial results for the fourth quarter and year ended December 31, 2012.

14 Feb 2013

Study demonstrates how CN2097 works to restore neural functions impaired by Angelman syndrome

In a new study in mice, a scientific collaboration centered at Brown University lays out in unprecedented detail a neurological signaling breakdown in Angelman syndrome, a disorder that affects thousands of children each year, characterized by developmental delay, seizures, and other problems.

14 Feb 2013

FDA grants orphan drug status to Lentigen’s LG631-CD34 for treatment of glioblastoma multiforme

Lentigen Corporation, a biotechnology company specializing in the development and manufacture of lentiviral gene delivery products, announced today that that the U.S. Food and Drug Administration (FDA) has granted orphan drug status to P140K methylguanine methyltransferase (MGMT) transduced human CD34 cells for bone marrow protection in the treatment of glioblastoma multiforme.

14 Feb 2013

Mindfulness practitioners gain enhanced control over sensory cortical alpha rhythms

Why does training in mindfulness meditation help patients manage chronic pain and depression? In a newly published neurophysiological review, Brown University scientists propose that mindfulness practitioners gain enhanced control over sensory cortical alpha rhythms that help regulate how the brain processes and filters sensations, including pain, and memories such as depressive cognitions.

14 Feb 2013

New paper advances scientific understanding of glycoproteins’ structure and function

A Simon Fraser University chemist is the lead author on a new paper that advances scientific understanding of the structure and function of glycoproteins, in particular the number and positioning of sugars on them.

14 Feb 2013

Triple-negative breast cancers more biologically diverse than previously believed

Triple-negative breast cancers are more biologically diverse than previously believed and classification should be expanded to reflect this heterogeneity, according to University of North Carolina researchers.

14 Feb 2013

Viewpoints: Obama prescription for Medicare is 'modest;' GOP doubts entitlement plan is serious

Somewhat more substantively, he called for a larger deficit-reduction deal built around loophole-closing tax reform and what he called "modest" reforms to Medicare and entitlements. In an apparent effort to rally Democrats to this cause, he called on "those of us who care deeply about programs like Medicare" to "embrace" reform.

14 Feb 2013

DBS can lead to long-term improvement in patients with neuropathic pain

For many patients with difficult-to-treat neuropathic pain, deep brain stimulation (DBS) can lead to long-term improvement in pain scores and other outcomes, according to a study in the February issue of Neurosurgery, official journal of the Congress of Neurological Surgeons.

14 Feb 2013

Tousled-like kinases play a key role in suppression and activation of herpesviruses

Kaposi's sarcoma-associated herpesvirus (KSHV) and Epstein-Barr virus (EBV) hide within the worldwide human population. While dormant in the vast majority of those infected, these active herpesviruses can develop into several forms of cancer.

14 Feb 2013

Dyax fourth quarter total revenues increase to $16.0 million

Dyax Corp. today announced financial results for the fourth quarter and year ended December 31, 2012.

14 Feb 2013

FDA allows Scioderm’s SD-101 IND application for Epidermolysis Bullosa to proceed

Scioderm announced that the US Food and Drug Administration (FDA) has reviewed and allowed the investigational new drug (IND) application for SD-101 to proceed. SD-101 is a topical treatment being developed for the treatment of Epidermolysis Bullosa (EB).

14 Feb 2013

Blood’s tendency to clot may contribute to white matter hyperintensities in post-menopausal women

New Mayo Clinic research suggests that blood may hold clues to whether post-menopausal women may be at an increased risk for areas of brain damage that can lead to memory problems and possibly increased risk of stroke. The study shows that blood's tendency to clot may contribute to areas of brain damage called white matter hyperintensities.

14 Feb 2013

Violence against pregnant women in India contributes to high maternal mortality, the Atlantic reports

The Atlantic examines the issue of violence against pregnant women in India. "In the aftermath of the high-profile gang rape of a 23-year-old medical student, discussions have raged in India about the regularity of violence against women," the magazine writes, adding, "As has been widely noted, the causes of the violence run deep. But they also are broad."

14 Feb 2013

CATT study clarifies value of genetic testing for age-related macular degeneration

New findings from a landmark clinical trial show that although certain gene variants may predict whether a person is likely to develop age-related macular degeneration (AMD), a potentially blinding eye disease that afflicts more than nine million Americans, these genes do not predict how patients will respond to Lucentis- and Avastin-, the two medications most widely used to treat the "wet" form of AMD.

13 Feb 2013

Examining politics of reaching NCD targets

Writing in the PLoS blog "Translational Global Health," Greg Paton, a public health consultant, discusses the history of and current discussions taking place surrounding global targets for non-communicable diseases (NCDs).

13 Feb 2013

AIDS.gov blog examines Global Fund's future

"During January's World Economic Forum, international leaders welcomed former U.S. Global AIDS Coordinator Mark Dybul as the new head of the Global Fund to Fight AIDS, Tuberculosis and Malaria," Deborah Derrick, president of Friends of the Global Fight Against AIDS, Tuberculosis and Malaria, writes in the AIDS.gov blog.

13 Feb 2013

Research News and Research

USAID blog reports on India's Call to Action Summit for Child Survival, Development

Link between Jagged-1 protein and bone formation

President Obama delivers SOTU address, mentioning trade agreements, AIDS-free generation

CELF6 genetic mutation may underlie common behaviors seen in people with autism

Targacept reports net loss of $15.9 million for fourth quarter 2012

Study demonstrates how CN2097 works to restore neural functions impaired by Angelman syndrome

FDA grants orphan drug status to Lentigen’s LG631-CD34 for treatment of glioblastoma multiforme

Mindfulness practitioners gain enhanced control over sensory cortical alpha rhythms

New paper advances scientific understanding of glycoproteins’ structure and function

Triple-negative breast cancers more biologically diverse than previously believed

Viewpoints: Obama prescription for Medicare is 'modest;' GOP doubts entitlement plan is serious

DBS can lead to long-term improvement in patients with neuropathic pain

Tousled-like kinases play a key role in suppression and activation of herpesviruses

Dyax fourth quarter total revenues increase to $16.0 million

FDA allows Scioderm’s SD-101 IND application for Epidermolysis Bullosa to proceed

Blood’s tendency to clot may contribute to white matter hyperintensities in post-menopausal women

Violence against pregnant women in India contributes to high maternal mortality, the Atlantic reports

CATT study clarifies value of genetic testing for age-related macular degeneration

Examining politics of reaching NCD targets

AIDS.gov blog examines Global Fund's future

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