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Preexisting rhinovirus infection and IFN induction in epithelium of asthma patients decreases SARS-CoV-2 infection

In a recent study, researchers explored the effects of RV, HDM, and SARS-CoV-2 on differentiated primary human bronchial epithelial cells (HBECs) in vitro and in experimental in vivo RV infection in healthy subjects and asthmatic patients.

22 Nov 2021

Characterization of B-cell receptor repertoires in COVID-19 patients

In a new study published in the journal Human Immunology, scientists sought to better understand how B-cell immune repertoire changes over time during SARS-CoV-2 infection by comprehensively characterizing the dynamics of immunoglobin heavy chain (IGH) repertoire in COVID-19 patients.

22 Nov 2021

Donor cells with clonal hematopoiesis may improve bone marrow transplant outcomes

Clonal hematopoiesis, a condition in which mutations associated with blood cancers are found in the blood of healthy people, is common with aging.

22 Nov 2021

AI could help better diagnose blood diseases

How can we better diagnose blood diseases? A research group led by Helmholtz Munich aims to answer this question with artificial intelligence (AI).

22 Nov 2021

Physical activity may reduce immune cell activation to improve brain health in Alzheimer's disease

No one will disagree that an active lifestyle is good for you, but it remains unclear how physical activity improves brain health, particularly in Alzheimer's disease.

22 Nov 2021

Study identifies key factor sustaining malignant tumor state

In a study published in Nature Cancer, researchers led by Prof. Cedric Blanpain, WELBIO investigator, Director of the Laboratory of Stem Cells and Cancer and Professor at the Université libre de Bruxelles, Belgium, demonstrated that NR2F2 is an essential regulator of malignant tumor state by controlling cancer stem cell and tumor maintenance in mouse and human cancers.

22 Nov 2021

Clearing old, dysfunctional cells in fat alleviates diabetes

Eliminating old, dysfunctional cells in human fat also alleviates signs of diabetes, researchers from UConn Health report. The discovery could lead to new treatments for Type 2 diabetes and other metabolic diseases.

22 Nov 2021

Singapore researchers develop ultra-sensitive 2D material sensor to detect breast cancer cells

Cells can produce unique electrical signals. These signals can be linked to various cancers, such as the breast, lung, liver, brain, pancreas and prostate cancers, meaning that they can be used as indicators for early cancer diagnosis.

22 Nov 2021

Cryo-EM reveals how the DNA replication machinery assembles at DNA damage sites

Cryogenic electron microscopy (cryo-EM) has enabled researchers to study how the DNA replication machinery assembles at sites where DNA is damaged.

22 Nov 2021

Novel carbon dots exhibit antimicrobial activity against gram-negative bacteria

Researchers synthesize carbon dots using different precursors and studied their antimicrobial effects in gram-negative bacteria.

22 Nov 2021

Impact of ultraviolet disinfection on nosocomial transmission of SARS-CoV-2 and other infectious diseases

A new review article determines the role of UV disinfection for nosocomial transmission of COVID-19 and other infectious diseases.

22 Nov 2021

Study shows porcine deltacoronavirus (PDCoV) is capable of zoonotic transfer

A team of researchers describes the presence of PDCoV strains in plasma samples of three Haitian children with acute undifferentiated febrile illness.

22 Nov 2021

Monitoring cellular metabolism for NAFLD/NASH liver disease research

In this interview, Jolanta Vidugiriene, a Senior Research Scientist at Promega Corporation, talks to News-Medical about tools for studying metabolism in NAFLD/NASH research.

From Promega Corporation 22 Nov 2021

Bioinformatics analysis identifies pathways involved in intestinal SARS-CoV-2 infection

Researchers recently used bioinformatics analysis techniques to explore the diseases caused by SARS-CoV-2 infection in the human digestive tract.

22 Nov 2021

Red blood cell distribution width as a biomarker for COVID-19

A review highlights the prospects and challenges of RDW as a predictive biomarker for viral infections, with a special focus on COVID-19 and hepatitis.

22 Nov 2021

CoronaVac vaccine booster strengthens protection against SARS-CoV-2

In a recent study published on the preprint medRxiv* server, an international team of scientists tested CoronaVac as a booster shot and measured its effects on immunity. Their findings showed increases in neutralizing antibodies and T cell response.

21 Nov 2021

Importance of cross-neutralizing antibodies against SARS-CoV-2 variants

A new study published in the journal mBio investigates different antibodies from convalescent donors that bind three separate domains of the SARS-CoV-2 spike. The results of this study suggest that the individuals exposed to the SARS-CoV-2 from the first wave have neutralizing antibodies against current variants.

21 Nov 2021

Sheep at low-risk for infection with SARS-CoV-2

A team of scientists from the US has recently evaluated the susceptibility of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection in sheep. The findings reveal that sheep are generally less susceptible to SARS-CoV-2 infection. However, the susceptibility is relatively higher for the alpha variant of the virus. The study is currently available on the bioRxiv preprint server.

21 Nov 2021

Study explores connections between COVID-19 severity and gene expression in immune cells

New research shows how genetic variations linked to severe cases of COVID-19 affect our immune cells.

21 Nov 2021

TXA drug has minimal impact in controlling blood loss in severely injured trauma patients

A recent study found that the drug tranexamic acid has minimal impact in controlling blood loss in severely injured trauma patients at the standard doses given, according to researchers at Washington University School of Medicine in St. Louis.

21 Nov 2021

B Cell News and Research

Preexisting rhinovirus infection and IFN induction in epithelium of asthma patients decreases SARS-CoV-2 infection

Characterization of B-cell receptor repertoires in COVID-19 patients

Donor cells with clonal hematopoiesis may improve bone marrow transplant outcomes

AI could help better diagnose blood diseases

Physical activity may reduce immune cell activation to improve brain health in Alzheimer's disease

Study identifies key factor sustaining malignant tumor state

Clearing old, dysfunctional cells in fat alleviates diabetes

Singapore researchers develop ultra-sensitive 2D material sensor to detect breast cancer cells

Cryo-EM reveals how the DNA replication machinery assembles at DNA damage sites

Novel carbon dots exhibit antimicrobial activity against gram-negative bacteria

Impact of ultraviolet disinfection on nosocomial transmission of SARS-CoV-2 and other infectious diseases

Study shows porcine deltacoronavirus (PDCoV) is capable of zoonotic transfer

Monitoring cellular metabolism for NAFLD/NASH liver disease research

Bioinformatics analysis identifies pathways involved in intestinal SARS-CoV-2 infection

Red blood cell distribution width as a biomarker for COVID-19

CoronaVac vaccine booster strengthens protection against SARS-CoV-2

Importance of cross-neutralizing antibodies against SARS-CoV-2 variants

Sheep at low-risk for infection with SARS-CoV-2

Study explores connections between COVID-19 severity and gene expression in immune cells

TXA drug has minimal impact in controlling blood loss in severely injured trauma patients

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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