Biomarker News and Research

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A biomarker is a biological molecule found in blood, other body fluids, or tissues that is a sign of a normal or abnormal process, or of a condition or disease. A biomarker may be used to see how well the body responds to a treatment for a disease or condition. Also called molecular marker and signature molecule.

Patient-derived organoids uncover new targets for chronic pancreatitis treatment

Around three million people worldwide struggle with chronic pancreatitis, a condition wherein the pancreas becomes inflamed, scarred, and painful.

14 Jul 2026

Experimental gene therapy reverses fragile X symptoms in mice

A gene therapy designed to replace the missing protein that causes fragile X syndrome restored several disease-relevant traits in a mouse model, according to a new study published in Gene Therapy.

14 Jul 2026

New review highlights astrocytes' role in chronic traumatic encephalopathy

Researchers from Kansas City University School of Medicine have published a scoping review examining the role of astrocytes in chronic traumatic encephalopathy (CTE).

14 Jul 2026

New report highlights top ten brain health breakthroughs for clinicians

"Understanding Breakthroughs in Brain Health: Top 10 Articles of 2025" - the latest "Top 10" report in the Gerontological Society of America's Insights & Implications in Gerontology series - presents a curated collection of the year's most impactful research on cognitive decline, dementia detection, and brain health across the lifespan, with a focus on actionable insights for primary care providers.

14 Jul 2026

Bifidobacterium-based oral vaccine enhances anti-tumor immunity in clinical study

A novel oral vaccine platform using genetically engineered Bifidobacterium could enhance anti-tumor immunity.

14 Jul 2026

Ultrasensitive biosensor detects early-stage liver fibrosis using small amount of blood

A research team led by Professor Jinsung Park of the Department of Biomechatronic Engineering at Sungkyunkwan University(SKKU), working jointly with Professor Pil-Soo Sung of the College of Medicine at the Catholic University of Korea and Professor Si-Hyun Bae, President of Eunpyeong St. Mary's Hospital, has developed an ultrasensitive electrochemical biosensor capable of accurately detecting "early-stage liver fibrosis"—a condition in which the liver progressively hardens—using only a small amount of blood.

14 Jul 2026

Researchers propose simple finger prick test to track metabolic health

Researchers writing in Frontiers in Science propose using simple tests to track metabolic health in non-communicable diseases, which cause three in four deaths worldwide.

14 Jul 2026

Dysregulation of immune regulator NF-κB drives major human diseases

NF‑κB controls genes involved in inflammation, immunity, cell survival, and proliferation. Triggered by cytokines (TNF‑α, IL‑1β), microbial products, or cellular stress, it translocates to the nucleus and induces pro‑inflammatory mediators.

13 Jul 2026

Novogene Europe launches Untargeted Metabolomics Service at Cambridge Omics Centre

Novogene Europe, a multiomics research services partner, today announced that it has strengthened its position as a multiomics partner with the launch of its Untargeted Metabolomics Service through its Cambridge Omics Centre.

From Novogene Europe 13 Jul 2026

Animal-free lung model unlocks better treatments for RSV in babies

Future therapies for respiratory syncytial virus (RSV) must target both the virus and its immune response to ensure babies get the best possible outcomes, finds a new study by researchers at UCL and Great Ormond Street Hospital for Children (GOSH).

13 Jul 2026

New generation approaches revive BET protein inhibitors in solid tumors

BET proteins, especially BRD4, drive oncogenic transcription in solid tumours. First‑generation inhibitors (JQ1, molibresib, birabresib) showed preclinical promise but failed clinically due to modest efficacy, dose‑limiting thrombocytopenia, and resistance (isoform switching, compensatory PI3K/AKT/WNT signalling).

11 Jul 2026

Damaged myelin alters sleep brain rhythms in neurological diseases

Scientists have discovered how damage to the myelin sheath – the insulating layer around nerve fibres – affects brain activity during sleep.

9 Jul 2026

UCSF and Samsung launch remote study on aging brain health

An innovative new study from the Neuroscape research center at UCSF, and consumer electronics giant Samsung seeks to understand decade-by-decade changes in brain health.

9 Jul 2026

Spear Bio to unveil novel Alzheimer’s disease immunoassays and fully automated instrument platform at AAIC 2026

Spear Bio, an innovator in ultrasensitive protein biomarker detection, today announced plans to unveil new SPEAR immunoassay and instrument innovations at the Alzheimer’s Association International Conference® 2026, taking place July 12–15 in London, UK.

From Spear Bio 9 Jul 2026

Direct-to-definitive toxicology screening: Moving beyond immunoassays in clinical toxicology

Discover expert insights into toxicology screening with mass spectrometry, reducing false results and improving patient safety in clinical toxicology.

From Waters Advanced Diagnostics 9 Jul 2026

Maternal diet may subtly shape breast milk immune signals

Research indicates that maternal dietary patterns can subtly affect the immune composition of breast milk, with implications for infant immune development.

9 Jul 2026

Study links PTSD to accelerated biological aging and chronic disease

Post-Traumatic Stress Disorder (PTSD) remains a common condition affecting World Trade Center (WTC) responders 25 years after the attack on the Twin Towers.

8 Jul 2026

LEAP2 hormone may predict anorexia nervosa relapse risk

People with anorexia nervosa have unusually high levels of a hormone called LEAP2 in their blood when they are in the acute phase of the disorder, according to research presented today (Thursday) at the Federation of European Neuroscience Societies (FENS) Forum 2026.

8 Jul 2026

Weill Cornell Medicine receives federal grant to study new gene therapy for Alzheimer's disease

The National Institute on Aging of the National Institutes of Health has awarded a five-year grant initially worth $8.37 million for Weill Cornell Medicine researchers to study a new gene therapy for Alzheimer's disease in people who have a high genetic risk of developing the condition.

8 Jul 2026

Study reveals how glial cells regulate brain injury and recovery

Traumatic brain injury (TBI) affects millions of people worldwide every year and remains a major cause of long-term disability, cognitive decline, and neurological complications.

8 Jul 2026