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UCL scientists design symbolic AI digital twins to treat cancer

In a new paper published in Cell Reports Medicine, the UCL team outline how they, in collaboration with a University of Cambridge team, developed a new type of treatment-predicting computer program that uses an individual's detailed genetic fingerprint to explore which treatments, if any, may kill their cancer – especially when standard treatments have failed.

26 Oct 2026

Proteins linked to Alzheimer's found to assist sperm cells

Unexpectedly, a kind of protein that is usually linked with diseases in the brain may play a vital role in semen, helping shepherd genetic material into sperm cells, scientists at Columbia's Zuckerman Institute report today in the research journal Molecular Cell.

26 Oct 2026

Smart probe makes aggressive breast cancer cells glow during surgery

Surgical removal of a tumor remains the primary defense against most solid cancers. However, for surgeons in the operating room, differentiating between the outer edges of a tumor and healthy tissue is a challenge.

26 Oct 2026

KAIST team develops neural chip to track Alzheimer's drug response

What happens in the brain after an Alzheimer's drug is administered? A joint research team led by KAIST has used a small, implantable neural chip to wirelessly monitor real-time changes in a neurotransmitter involved in memory and learning.

26 Oct 2026

Researchers discover how faulty matrix structure leads to cell death in newly formed bone

Bone cells called osteocytes help maintain skeletal strength, but how newly formed osteocytes survive remains unclear.

26 Oct 2026

New archiving technique reveals past gene activity in cells

Information on what a cell did a few hours or days ago is generally unavailable to researchers, who can only measure the cell's current status.

26 Oct 2026

Next generation KRAS inhibitor divarasib significantly extends lung cancer survival

Patients with previously treated advanced KRAS G12C-mutant non-small cell lung cancer (NSCLC) lived significantly longer and saw improved disease control when treated with the next-generation KRAS targeted therapy divarasib, according to researchers from The University of Texas MD Anderson Cancer Center.

26 Oct 2026

Rome changed Iberia’s ancestry more than the migrations that followed

Researchers analyzed ancient DNA from 243 individuals who lived in Iberia between 100 and 800 CE, alongside data from 58 previously studied individuals, to examine how Roman rule and early medieval migrations affected population ancestry. They found substantial Eastern Mediterranean- and North African-related ancestry contributions during Roman times, while later migrations introduced Central-Northern European ancestry without widespread replacement of the Hispano-Roman population.

25 Oct 2026

PFAS levels in United States drinking water may be underestimated

Common ways of reporting perfluoroalkyl and polyfluoroalkyl substances (PFAS)-the man-made, so-called forever chemicals that pose environmental and health threats-could underestimate the concentration of PFAS in United States drinking water by as much as half, finds a study publishing October 23 in the Cell Press journal Cell Reports Sustainability.

24 Oct 2026

Nearly one third of patients with advanced melanoma saw tumors disappear completely after receiving TIL therapy plus pembrolizumab immunotherapy

Results from a clinical trial have revealed nearly one third (29.2 percent) of patients with advanced melanoma saw their tumors disappear completely on scans after receiving lifileucel TIL therapy alongside an immune checkpoint inhibitor, pembrolizumab, as a first-line treatment.

24 Oct 2026

Newly discovered protein controls the space between mitochondrial membranes

Mitochondria are the tiny powerpacks that supply most of the energy our cells need. Their ability to generate this energy relies on a distinctive architecture: two membranes, one tucked inside the other, separated by a narrow gap called the intermembrane space (IMS).

23 Oct 2026

Ancient virus may help explain differences in human and chimpanzee brains

Pandemics can arise wherever animal or human populations are sufficiently large, and they are not confined to the modern age.

23 Oct 2026

Six-gene score could improve survival predictions for acute myeloid leukemia

The activity of six different genes can help determine patient survival of acute myeloid leukemia (AML), according to a study published today in Science Advances.

23 Oct 2026

Study reveals how cancer cells survive chemotherapy in a zombie-like state

Scientists at Trinity College Dublin have made an important breakthrough in understanding how cancer cells can evade the cell-killing effects of chemotherapy and enter a "zombie-like state", called premature senescence, that can attract the wound healing properties of the immune system.

23 Oct 2026

Taurine helps regulate inflammation linked to aging, Yale study finds

Sustained low-level inflammation is a hallmark of the aging process. The accumulating damage persistently activates the innate immune system-the body's first line of defense-leading to what is known as inflammaging, functional decline and chronic diseases of old age.

23 Oct 2026

KRAS-targeting vaccine prompts immune responses in pancreatic cancer patients

An investigational vaccine helped the immune system recognize and respond to mutations that drive most pancreatic cancers, according to results from a randomized phase 2 clinical trial led by Mayo Clinic researchers.

23 Oct 2026

Shared meiosis proteins show surprising functional differences across animals

Every egg cell and sperm cell depends on meiosis, a tightly choreographed process in which chromosomes find their partners, exchange genetic material, and then divide.

23 Oct 2026

Targeted drug extends survival across diverse pancreatic cancer patient groups

A new analysis of a phase 3 clinical trial found that the targeted drug daraxonrasib improved survival compared with standard chemotherapy across multiple groups of patients with advanced pancreatic cancer, including those with different RAS mutations and those without an identified RAS mutation.

23 Oct 2026

PARP1 remodels nucleosomes to help cells repair damaged DNA

When DNA is damaged, cellular processes respond and repair the DNA. Inhibiting DNA damage repair can be therapeutically beneficial in cancers with genetic vulnerabilities related to DNA damage response.

23 Oct 2026