Confocal microscopy News and Research

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Hyperbranched polylysine nanopolymer as potential broad-spectrum antiviral against SARS-CoV-2

The findings from this study suggest that HPNs may inhibit viral replication and budding.

27 Sep 2021

New 3D pancreatic cancer model could be used to develop and test targeted treatments

An international team of scientists have created a three-dimensional (3D) pancreatic cancer tumour model in the laboratory, combining a bioengineered matrix and patient-derived cells that could be used to develop and test targeted treatments.

24 Sep 2021

Research offers insights to restore blood vessel integrity during sepsis, other conditions

Sepsis occurs when the body works so hard to fight an infection that the over-activated immune system harms a patient's own tissues as collateral damage.

31 Aug 2021

Scientists identify the main components driving amyloid beta-associated synapse degeneration

Healthy adult brains are endowed with a vast number of synapses, structures that relay signals across nerve cells to enable communications, information processing and storage throughout the nervous system.

18 Aug 2021

Activation of integrins by SARS-CoV-2 may be key to infection

A new study describes the key role of membrane proteins called integrins, which are present in epithelia, in the entry and propagation of SARS-CoV-2.

25 Jul 2021

Novel optical device could open new avenues in advanced microscopy

What if a microscope allowed us to explore the 3D microcosm of blood vessels, nerves, and cancer cells instantaneously in virtual reality? What if it could provide views from multiple directions in real time without physically moving the specimen and worked up to 100 times faster than current technology?

1 Jul 2021

Study examines SARS-CoV-2 replication in cells using super-resolution microscopy

Despite tremendous efforts by the global scientific community to curb the spread of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), by developing more efficient testing protocols, therapies, and vaccines at a rapid pace, relatively little is known about the dynamics of SARS-CoV-2 replication within cells.

18 Jun 2021

New transparent material can capture respiratory droplets effectively from air

Although plexiglass barriers are seemingly everywhere these days -- between grocery store lanes, around restaurant tables and towering above office cubicles -- they are an imperfect solution to blocking virus transmission.

17 Jun 2021

Smoking and vaping increase ACE2 levels and virus spike binding in airway epithelium

A new bioRxiv preprint attempts to make some sense of why certain people experience more severe forms of COVID-19 as compared to others by pointing to the increase in virus binding that occurs in the presence of smoking or vaping.

9 Jun 2021

Two repurposed drugs inhibit SARS-CoV-2 entry factors in a synergistic manner

A preprint paper uploaded to the bioRxiv* server shows how combining drugs targeting different entry factors of the host cell may prevent infection by the virus.

3 Jun 2021

Phosphatidic acid is a key common substrate for hepatitis C and SARS-CoV-2 replication

A new study, released as a preprint on the bioRxiv* server, focuses on the lipid molecule called phosphatidic acid (PA), showing its crucial role in the replication of this virus, and thus its potential as a target for therapeutic intervention.

13 May 2021

Ravi Sheth receives 2020 Hertz thesis prize for transforming microbial research

Hertz Fellow Ravi Sheth says his lab in the Brooklyn Navy Yard is "like a Willy Wonka factory of microbes" geared toward improving the taste and safety of food and beverages.

4 May 2021

A new 3D model for myotonic dystrophy

Myotonic dystrophy is a hereditary degenerative neuromuscular disease that occurs mainly in adults, affecting about 50,000 people only in Spain.

4 May 2021

$High-resolution imaging, 3D computer modeling reveal the fractal nature of neurons$

High-resolution imaging, 3D computer modeling reveal the fractal nature of neurons

High-resolution imaging and 3D computer modeling show that the dendrites of neurons weave through space in a way that balances their need to connect to other neurons with the costs of doing so.

3 Mar 2021

Commonly used sweeteners may promote antibiotic resistance

Researchers in Australia have conducted a study showing that commonly used nonnutritive sweeteners can promote the spread of antibiotic-resistant genes in the intestine.

28 Feb 2021

New N501Y SARS-CoV-2 mutations increase binding to host cell receptor

A team of researchers used several assays, atomic force microscopy, and simulations to determine that the N501Y mutation in the virus’s receptor-binding domain (RBD) increased the interaction of the virus with the angiotensin-converting enzyme 2 (ACE2) receptor.

17 Feb 2021

Confocal microscopy News and Research

Hyperbranched polylysine nanopolymer as potential broad-spectrum antiviral against SARS-CoV-2

New 3D pancreatic cancer model could be used to develop and test targeted treatments

Research offers insights to restore blood vessel integrity during sepsis, other conditions

Scientists identify the main components driving amyloid beta-associated synapse degeneration

Activation of integrins by SARS-CoV-2 may be key to infection

Novel optical device could open new avenues in advanced microscopy

Study examines SARS-CoV-2 replication in cells using super-resolution microscopy

New transparent material can capture respiratory droplets effectively from air

Smoking and vaping increase ACE2 levels and virus spike binding in airway epithelium

Two repurposed drugs inhibit SARS-CoV-2 entry factors in a synergistic manner

Phosphatidic acid is a key common substrate for hepatitis C and SARS-CoV-2 replication

Ravi Sheth receives 2020 Hertz thesis prize for transforming microbial research

A new 3D model for myotonic dystrophy

High-resolution imaging, 3D computer modeling reveal the fractal nature of neurons

Commonly used sweeteners may promote antibiotic resistance

New N501Y SARS-CoV-2 mutations increase binding to host cell receptor

Webinar: High-Content Imaging on Human Pluripotent Stem Cell Research

Study finds locations of early prion protein accumulation in the eye

Avalanching nanoparticles may advance real-time bioimaging of cell's organelles and proteins

Copper gluconate supplementation could reduce SARS-CoV-2 infection in vitro

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