Ear News and Research

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Gene editing restores hearing and balance in adult mice with DFNA41 deafness

Zheng-Yi Chen, DPhil, associate scientist at the Eaton-Peabody Laboratories, and Ines and Fredrick Yeatts Chair in Otolaryngology, at Mass Eye and Ear, is the senior and co-corresponding author of a paper published in the Journal of Clinical Investigation, "Single Dose Genome Editing Therapy Rescues Auditory and Vestibular Functions in Adult Mice with DFNA41 Deafness."

14 Aug 2025

Prenatal acetaminophen linked to higher risk of autism and ADHD

Researchers at the Icahn School of Medicine at Mount Sinai have found that prenatal exposure to acetaminophen may increase the risk of neurodevelopmental disorders, including autism spectrum disorder and attention-deficit/hyperactivity disorder (ADHD), in children.

14 Aug 2025

Mount Sinai receives major grant for new initiative dedicated to reducing cancer care disparities

The American Cancer Society (ACS) has awarded The Tisch Cancer Institute at the Icahn School of Medicine at Mount Sinai a $4.08 million grant to establish the Cancer Health Research Center at Mount Sinai, a new initiative dedicated to reducing cancer-related health inequities across New York City.

12 Aug 2025

New subcutaneous EEG device offers breakthrough in epilepsy monitoring

New research from the Institute of Psychiatry, Psychology & Neuroscience (IoPPN) at King's College London in partnership with the Mayo Clinic and UNEEG medical, has found that an electronic device placed under the scalp is an effective and feasible means of accurately tracking epilepsy.

11 Aug 2025

Brain aging may be slower and more layered than previously thought

The human brain ages less than thought and in layers – at least in the area of the cerebral cortex responsible for the sense of touch.

11 Aug 2025

Hypoglossal nerve stimulator shows promise for treating sleep apnea in children with Down syndrome

Sleep apnea, or difficulty breathing at night, is common among children with Down syndrome-affecting up to 80% compared to just 5% of the general pediatric population.

5 Aug 2025

Vagus nerve stimulation enhances the effects of compassion meditation training

Stimulating the vagus nerve with a device attached to the outer ear can help make compassion meditation training more effective at boosting people's capacity for self-kindness and mindfulness, finds a new study led by University College London (UCL) researchers.

5 Aug 2025

Mapping the brain’s serotonin switch could lead to better antidepressants

In a discovery that could guide the development of next-generation antidepressants and antipsychotic medications, researchers at the Icahn School of Medicine at Mount Sinai have developed new insights into how a critical brain receptor works at the molecular level and why that matters for mental health treatments.

1 Aug 2025

Hearing loss impacts employment and income among young adults

Hearing loss is the most common form of sensory disability. Approximately 1.6 billion people around the world currently live with from some degree of hearing loss, and the WHO has forecast that this number will rise to 2.5 billion by 2050.

1 Aug 2025

Updated guideline aims to identify quality improvement opportunities in managing adult sinusitis

The American Academy of Otolaryngology–Head and Neck Surgery Foundation (AAO-HNSF) published the Clinical Practice Guideline (CPG): Adult Sinusitis Update today in Otolaryngology–Head and Neck Surgery.

31 Jul 2025

The Mount Sinai Hospital named among nation’s top 20 for care excellence

The Mount Sinai Hospital, the flagship hospital of Mount Sinai Health System, was listed among the nation's top 20 hospitals for care excellence by U.S. News & World Report for 2025-26, marking the 10th consecutive year the hospital has been listed on the publication's "Honor Roll."

29 Jul 2025

New imaging tool measures inner ear fluid to assess hearing loss

Optical coherence tomography (OCT), a tool routinely used to diagnose and plan treatment for eye diseases, has now been modified to collect images of the inner ear.

23 Jul 2025

Zebrafish reveal how two genes independently drive sensory organ regeneration

Researchers identified that two cyclin D genes, ccndx and ccnd2a, independently regulate distinct stem and progenitor cell populations during zebrafish sensory organ regeneration. The findings reveal that regeneration can proceed via alternative pathways even when one gene is disrupted, providing new insight into tissue repair mechanisms.

20 Jul 2025

Niigata University team reports novel treatment for IDH2-mutant brainstem glioma

A group led by the Department of Neurosurgery at the Brain Research Institute, Niigata University, has successfully treated a patient with a brainstem glioma harboring a rare IDH2 mutation.

17 Jul 2025

Routine vaccines may be the key to fighting antibiotic resistance

A study reveals that rising vaccine coverage in children is linked to reduced antibiotic prescriptions, suggesting a shift in the fight against drug resistance.

16 Jul 2025

Brain's tiny region dictates how memories are formed and separated

Life may unfold as a continuous stream, but our memories tell a different story. We do not recall the past as one long, unbroken text. Instead, we remember it as a series of meaningful events, like how sentences are structured with grammar and punctuation.

16 Jul 2025

Blocking Epac1 protein slows lung fibrosis in preclinical models

Researchers at the Icahn School of Medicine at Mount Sinai and collaborators have identified a previously overlooked protein, Epac1, as a key driver of idiopathic pulmonary fibrosis (IPF), a chronic and progressive lung-scarring disease.

15 Jul 2025

Nasal antibody spray shields mice from pollen-triggered allergies and asthma

Intranasal delivery of a monoclonal IgG1 antibody targeting mugwort pollen protected mice from allergic rhinitis and asthma symptoms, without lowering systemic IgE levels. This localized, non-invasive approach dampened Th2 inflammation and preserved healthy airway tissue in sensitized mice.

14 Jul 2025

Scientists discover how two distinct genes guide regeneration of sensory cells in zebrafish

While humans can regularly replace certain cells, like those in our blood and gut, we cannot naturally regrow most other parts of the body. For example, when the tiny sensory hair cells in our inner ears are damaged, the result is often permanent hearing loss, deafness, or balance problems.

14 Jul 2025

Monoclonal antibody delivered through the nose blocks hay fever in mice

Approximately 40% of the European population are allergic to pollen, and their symptoms cause an estimated loss of 100 million school- and workdays every year.

11 Jul 2025