Estradiol News and Research

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Estradiol is a sex hormone. Mislabelled the "female" hormone, it is also present in males; it represents the major estrogen in humans. Estradiol has not only a critical impact on reproductive and sexual functioning, but also affects other organs including the bones.

Gut bacteria and pregnancy

Researchers from Bar-Ilan University have found that with pregnancy there is a change in the composition of gut bacteria in women. This could be associated with the changing hormonal status they speculate. The results of their study titled, “Progesterone Increases Bifidobacterium Relative Abundance during Late Pregnancy,” were published in the latest issue of the journal Cell Reports.

17 Apr 2019

Empathy and hormones could account for aggressive behavior in children, shows study

The research group in the Psychobiology section of the Department of Basic Psychological Processes and their Development of the UPV/EHU's Faculty of Psychology has spent many years studying aggressive behaviour in children.

17 Apr 2019

GC-MS/MS of dried urine is a ‘good surrogate’ for serum testing of hormones

Researchers have shown that analyzing dried urine extracts with GC-MS/MS to assess levels of reproductive hormones in pre-and post-menopausal women provides similar results to radioimmunoassays using serum samples.

5 Apr 2019

Higher levels of sex hormones in older men related to lower biological age

Older men tend to have lower biological age if they have higher levels of sex hormones, particularly the estradiol form of estrogen, a large new study from Australia finds.

26 Mar 2019

The high cost of sex: Insurers often don’t pay for drugs to treat problems

For some older people, the joy of sex may be tempered by financial concerns: Can they afford the medications they need to improve their experience between the sheets?

19 Feb 2019

New PET imaging agent may help measure efficacy or failure of hormone therapy for breast cancer

Physicians may soon have a new way to measure the efficacy or failure of hormone therapy for breast cancer patients, according to new research published in the February issue of The Journal of Nuclear Medicine.

12 Feb 2019

KU researcher studies how estrogen may protect menisci between thighbone and shinbone

More than 30 million Americans suffer from osteoarthritis of the knee, according to the Centers for Disease Control and Prevention.

9 Jan 2019

DHEA therapy may help prevent bone loss and increase muscle mass in older women

Women 55 and older have an increased risk of bone and muscle loss but therapy with the hormone Dehydroepiandrosterone may help prevent bone loss and increase muscle mass in older women, according to a new study led by Catherine M. Jankowski, PhD, FACSM, an exercise physiologist and associate professor at the University of Colorado College of Nursing at the Anschutz Medical Campus.

5 Dec 2018

Bariatric surgery increases testosterone levels in obese male patients

Men who have undergone bariatric surgery as a long-term way of losing weight might also benefit from increased testosterone levels post-surgery.

31 Oct 2018

TherapeuticsMD announces FDA approval of BIJUVA capsules to manage vasomotor symptoms of menopause

TherapeuticsMD, Inc., an innovative women's healthcare company, today announced that the United States Food and Drug Administration has approved BIJUVA (estradiol and progesterone) capsules, 1 mg/100 mg, the first and only FDA-approved bio-identical hormone therapy combination of estradiol and progesterone in a single, oral capsule for the treatment of moderate to severe vasomotor symptoms (commonly known as hot flashes or flushes) due to menopause in women with a uterus.

29 Oct 2018

Drugs approved for breast cancer treatment are effective and well tolerated in men

There is growing evidence that drugs approved for the treatment of breast cancer in women are also effective and well tolerated in men, according to the largest real-life study yet to investigate treatment and outcomes in men with breast cancer and two further studies to be reported at ESMO 2018.

23 Oct 2018

Zoledronic acid increases disease-free survival in premenopausal women with HR+ early breast cancer

Adjuvant treatment with the bone sparing drug zoledronic acid plus hormonal therapy with the aromatase inhibitor letrozole significantly increases disease-free survival compared to tamoxifen in premenopausal women with hormone receptor positive (HR+) early breast cancer, according to results reported at ESMO 2018 Congress in Munich.

22 Oct 2018

Study: Neurons regulating reproductive hormone release have different activity in epileptic mice

Mice with epilepsy have altered patterns of neuron activity in the portion of the brain that controls the reproductive endocrine system, University of Illinois researchers report in a new study. Furthermore, the differences in neuron activity in female mice fluctuate across the reproductive cycle, the team found.

15 Oct 2018

FDA approves first vaginal ring contraceptive that can be used for one year

The U.S. Food and Drug Administration today approved Annovera (segesterone acetate and ethinyl estradiol vaginal system), which is a combined hormonal contraceptive for women of reproductive age used to prevent pregnancy and is the first vaginal ring contraceptive that can be used for an entire year.

10 Aug 2018

New study demonstrates little effect of hormone therapy on artery thickness

Heart disease is still the number one killer of US women, and hormone therapy remains a top treatment for menopause symptoms.

18 Jul 2018

Hormone lab tests not necessary for most teens with gynecomastia

Routine assessment by an endocrinologist and laboratory tests to measure hormone levels aren't necessary in most adolescent boys with gynecomastia, concludes a study in the July issue of Plastic and Reconstructive Surgery, the official medical journal of the American Society of Plastic Surgeons.

30 Jun 2018

Study: Administration of endocrine disruptor causes epigenetic changes in pregnant sow's DNA

The public debate on endocrine disrupting chemicals- exogenous substances that have the same or similar effects as endogenous hormones - has been going on for some time.

30 Jun 2018

Estrogen may also play a role in migraine for men

While it has been known that estrogen plays a role in migraine for women, new research shows that the female sex hormone may also play a role in migraine for men, according to a small study published in the June 27, 2018, online issue of Neurology®, the medical journal of the American Academy of Neurology.

28 Jun 2018

Study identifies factors that contribute to vaginal dryness

It's a common problem that only gets worse during the menopause transition; yet, no one wants to talk about it, and even fewer women are doing anything to correct it.

20 Jun 2018

Study finds combination therapy to be safe, effective for treatment of male infertility

Two drugs that are commonly used off-label in the treatment of male infertility are clomiphene citrate (CC) and anastrozole (AZ); however, data are lacking on the use of combination CC+AZ therapy.

6 Jun 2018