Gastroenterology News and Research

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Gastroenterology is the branch of medicine where the digestive system and its disorders are studied.

Single-cell transcriptomics reveals new players in liver regeneration

The liver is remarkable for its ability to regenerate after injury, yet when this process fails, acute liver failure (ALF) carries devastating outcomes.

2 Sep 2025

Cellular purging process may help injured cells revert to stem cell-like state more rapidly

Now, a new study in mice led by researchers at Washington University School of Medicine in St. Louis and the Baylor College of Medicine reveals a previously unknown cellular purging process that may help injured cells revert to a stem cell-like state more rapidly.

29 Aug 2025

New global consensus offers hope for women with inflammatory bowel disease during pregnancy

For women with inflammatory bowel disease (IBD), pregnancy can be an uncertain time due to limited clinical data about how IBD medications impact pregnancy outcomes and infants who have been exposed to IBD medications in utero.

28 Aug 2025

Inflammatory bowel disease in Nigeria reveals unique clinical patterns and challenges

Inflammatory bowel disease (IBD) is a chronic condition with significant health implications worldwide. In Nigeria, data on its prevalence and characteristics are limited, highlighting the need for comprehensive studies to better understand its epidemiology and clinical features in the region.

28 Aug 2025

Longitudinal study reveals how GLP-2 analog therapy transforms the intestinal environment

Researchers from Japan discover that glucagon-like peptide-2 (GLP-2) analogs can deeply and beneficially reshape the intestinal environment.

27 Aug 2025

Transcutaneous vagal nerve stimulation shows promise for gastrointestinal disorders

Imbalanced autonomic function, characterized by reduced vagal activity and sympathetic dominance, is increasingly recognized in various gastrointestinal (GI) disorders.

27 Aug 2025

Healthy diet and physical activity reduce risk of alcohol-related liver-specific mortality

A novel study investigating how physical activity and diet quality interact with different levels and patterns of alcohol consumption shows that healthy eating and increased levels of physical activity significantly lower the risk of alcohol-attributable liver-related mortality.

27 Aug 2025

Shared gene signatures reveal metabolic dysfunction in liver cirrhosis and acute-on-chronic liver failure

Chronic liver cirrhosis (LC) and acute-on-chronic liver failure (ACLF) are interconnected hepatic disorders associated with substantial morbidity and mortality.

27 Aug 2025

Family history of liver disease significantly raises risk of severe alcohol-related hepatitis

In a groundbreaking study, research scientists from the Indiana University School of Medicine and Regenstrief Institute found that individuals with a parent who died from liver disease face more than double the risk of developing alcohol-associated hepatitis, one of the deadliest forms of alcohol-related liver disease, compared with similar heavy drinkers without that family history.

26 Aug 2025

Shame linked to lower quality of life in people with gut disorders

Feelings of shame are linked to reduced quality of life - as shown by the first study to measure shame as a factor influencing the connection between chronic gastrointestinal disorders and mental health.

25 Aug 2025

Carriers of colibactin-producing E. coli face threefold increase in colorectal cancer risk

Researchers from Kyoto Prefectural University of Medicine and collaborating Japanese institutions found that patients carrying colibactin-producing Escherichia coli (pks+ E. coli) in their colon polyps were more than three times as likely to have a history of colorectal cancer compared to those without the bacterium.

22 Aug 2025

Breakthroughs in diagnosis and therapy for transthyretin amyloidosis

Transthyretin amyloidosis (ATTR) is caused by the misfolding and aggregation of the transthyretin (TTR) protein, leading to multi-organ damage.

21 Aug 2025

Physician retention in New York reaches highest level in nearly a decade

The percentage of physicians who go on to practice in New York State after completing their residency training continues to climb.

19 Aug 2025

Landmark robotic spine surgery advances pediatric orthopedic care at Ochsner Children’s

Ochsner Children's has achieved a major milestone by performing the first robotic-assisted pediatric spine deformity surgery in Louisiana and the Gulf South.

18 Aug 2025

Better control of childhood EoE-associated inflammation reduces esophagus stiffening and complications

Researchers from Children's Hospital of Philadelphia (CHOP) and Children's Hospital Colorado have found that better control of chronic eosinophilic esophagitis (EoE)-associated inflammation during childhood leads to less stiffening of the esophagus, resulting in fewer disease complications.

18 Aug 2025

Helicobacter pylori eradication therapy linked to increased risk of reflux oesophagitis

The management of Helicobacter pylori (H. pylori), a globally prevalent gastric pathogen, has long been centered on its eradication to prevent peptic ulcers, gastric malignancies, and related gastrointestinal complications.

14 Aug 2025

Microbial DNA signature in the blood differentiates primary liver cancer from metastatic colorectal cancer

Determining whether a cancerous tumor originated in a given location or spread there from another tissue or organ in the body is important when assessing the likely course of a patient's disease.

14 Aug 2025

PFAS exposure increases risk of weight regain after adolescent bariatric surgery

Adolescents who undergo bariatric surgery face a higher risk of weight regain, which can undermine treatment success and long-term health, if they have elevated blood levels of per- and polyfluoroalkyl substances (PFAS) prior to the procedure, according to new USC research.

14 Aug 2025

AI use in colonoscopy may weaken doctors' detection skills over time

The introduction of artificial intelligence (AI) to assist colonoscopies is linked to a reduction in the ability of endoscopists (health professionals who perform colonoscopies) to detect precancerous growths (adenomas) in the colon without AI assistance, according to a paper published in The Lancet Gastroenterology & Hepatology journal.

13 Aug 2025

Blocking CREB may prevent alcohol-related pancreatic cancer

Despite increasing evidence linking alcohol consumption to cancer, little is known about the biological mechanisms behind the association.

12 Aug 2025

Gastroenterology News and Research

Further Reading

Single-cell transcriptomics reveals new players in liver regeneration

Cellular purging process may help injured cells revert to stem cell-like state more rapidly

New global consensus offers hope for women with inflammatory bowel disease during pregnancy

Inflammatory bowel disease in Nigeria reveals unique clinical patterns and challenges

Longitudinal study reveals how GLP-2 analog therapy transforms the intestinal environment

Transcutaneous vagal nerve stimulation shows promise for gastrointestinal disorders

Healthy diet and physical activity reduce risk of alcohol-related liver-specific mortality

Shared gene signatures reveal metabolic dysfunction in liver cirrhosis and acute-on-chronic liver failure

Family history of liver disease significantly raises risk of severe alcohol-related hepatitis

Shame linked to lower quality of life in people with gut disorders

Carriers of colibactin-producing E. coli face threefold increase in colorectal cancer risk

Breakthroughs in diagnosis and therapy for transthyretin amyloidosis

Physician retention in New York reaches highest level in nearly a decade

Landmark robotic spine surgery advances pediatric orthopedic care at Ochsner Children’s

Better control of childhood EoE-associated inflammation reduces esophagus stiffening and complications

Helicobacter pylori eradication therapy linked to increased risk of reflux oesophagitis

Microbial DNA signature in the blood differentiates primary liver cancer from metastatic colorectal cancer

PFAS exposure increases risk of weight regain after adolescent bariatric surgery

AI use in colonoscopy may weaken doctors' detection skills over time

Blocking CREB may prevent alcohol-related pancreatic cancer

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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