Heart Failure News and Research

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Heart failure (HF) is a condition in which a problem with the structure or function of the heart impairs its ability to supply sufficient blood flow to meet the body's needs. It should not be confused with cardiac arrest or myocardial infarction.

Muscle-specific molecular signal regulates how human heart cells produce and utilize critical energy

Researchers have identified a key protein that may help failing hearts regain function, offering new insight into why some hearts recover while others do not.

21 May 2026

Pregnancy magnifies heart risk, but age alone does not explain why

A large U.S. cohort-crossover study found that pregnancy and the postpartum period were linked to about a seven-fold higher relative risk of major adverse cardiovascular events compared with patients’ nonpregnant baseline risk. This relative risk increase did not vary by maternal age, suggesting pregnancy broadly amplifies existing cardiovascular risk rather than making older age itself the driver of pregnancy-specific cardiovascular complications.

20 May 2026

Patient intuition leads to urgent open-heart surgery at NYU Langone Hospital—Brooklyn

Shana Hale, a Brooklyn mother of two and a technology executive, noticed a mild burning sensation in her chest during her daily walks last summer.

20 May 2026

560-610 minutes of exercise a week linked to substantial cardiovascular health benefits

Adults should aim to do between 560 and 610 minutes a week of moderate to vigorous physical activity to achieve a substantial reduction in the risk of heart attacks and stroke, suggest the findings of an observational study published online in the British Journal of Sports Medicine.

19 May 2026

The Goldilocks sleep zone: study links too little and too much sleep to biological aging

The Nature study introduces “Sleep Chart,” a framework linking self-reported sleep duration with 23 biological aging clocks derived from MRI, plasma proteomics, and metabolomics. Across UK Biobank participants, the lowest biological age gaps generally appeared between 6.4 and 7.8 hours of sleep, while shorter and longer sleep were associated with higher disease and mortality risk.

14 May 2026

Study warns of rising cognitive impairment following a heart attack

The chance of developing cognitive impairment was significantly higher for people who have had a heart attack, according to a study published today in Stroke, the peer-reviewed scientific journal of the American Stroke Association, a division of the American Heart Association.

14 May 2026

New trial aims to improve ATTR-CM diagnosis in heart failure

Transthyretin amyloid cardiomyopathy (ATTR-CM) is an increasingly recognized yet frequently underdiagnosed cause of heart failure, particularly among older adults.

13 May 2026

Study improves prediction of dangerous outcomed from hypertrophic cardiomyopathy

A sweeping international study has identified ways to detect patients who are at serious risk of sudden death, heart failure or other dangerous outcomes from heart thickening known as hypertrophic cardiomyopathy.

13 May 2026

Two leading heart risk tools pass a major global test

A multinational Nature Medicine validation study found that PREVENT and SCORE2 cardiovascular risk equations performed generally well across 6.4 million people from observational cohorts and randomized trials. The findings support broader use of these tools for CVD risk stratification, while highlighting the need for local calibration and more validation in underrepresented regions.

11 May 2026

New model improves outcome predictions for patients with hypertrophic cardiomyopathy

Findings from a study supported in part by the National Institutes of Health (NIH) have identified a new model for predicting outcomes for hypertrophic cardiomyopathy (HCM), a heart condition with a prevalence of 1 in 500 people and a frequent cause of sudden cardiac death.

11 May 2026

Greater weight loss from GLP-1 drugs lowers health complication risk

New research to be presented at this year's European Congress on Obesity (ECO 2026, Istanbul, Turkey, 12-15 May) shows that, following treatment for obesity or diabetes or both using incretin-based drugs, losing more weight versus less weight, and losing a little weight versus gaining weight, both lead to relatively lower risk of obesity-related conditions.

10 May 2026

Heart disease risk prediction tool proves effective across global populations

A tool developed by the American Heart Association (AHA), proven to accurately predict heart disease risk for Americans, can be applied to the global population, a new study led by NYU Langone Health shows.

7 May 2026

Popular GLP-1 drugs significantly reduce major cardiovascular events,

Researchers evaluate the long-term cardiovascular safety and efficacy of GLP-1RAs in high-risk populations.

6 May 2026

KIF13B protects heart function during sepsis by regulating lipid metabolism

Sepsis, a life-threatening condition caused by dysregulated host response to infection, remains a major cause of global mortality.

5 May 2026

High-intensity interval exercise is most effective for heart patients

Endothelial dysfunction is a hallmark of cardiovascular disease (CVD) and plays a central role in vascular inflammation, thrombosis, and impaired vasodilation.

4 May 2026

GLP-1 drugs reduce risk of major adverse cardiovascular events

New research has shown that GLP‑1 weight-loss drugs deliver protection against heart attacks, strokes and premature death over a sustained period of time.

30 Apr 2026

Meth use accounts for nearly 1 in 6 heart attacks, California study shows

Methamphetamine (meth) use accounted for nearly 15% of heart attacks for a decade in a northern California study, published today in the Journal of the American Heart Association, an open access, peer-reviewed journal of the American Heart Association.

30 Apr 2026

New scientific statement defines brain health across life

Brain health isn't determined only by genetics or what happens later in life. A growing body of research shows that a range of factors-from mental health and sleep to environment, lifestyle and social conditions-play a powerful role in shaping how the brain functions and ages.

28 Apr 2026

Ablation can lead to better outcomes for patients with advanced atrial fibrillation

A minimally invasive heart procedure may be a better first-line treatment than medication for people living with advanced forms of atrial fibrillation, according to a major international clinical trial led by researchers at the University of British Columbia.

27 Apr 2026

Twice-yearly blood pressure treatment could reshape hypertension care, but doctors warn against a “fire-and-forget” approach

Long-acting RNA interference therapy for hypertension could shift blood pressure control from daily pill-taking to scheduled, system-led protection. But the authors warn that this “vaccine-like” model must preserve lifestyle support, monitoring, and follow-up to avoid clinical disengagement.