Liquid Chromatography News and Research

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Targeting obesity: findings reveal a new molecular pathway involved in energy homeostasis regulation

Study outlines molecular mechanisms to aid the development of new therapies to manage obesity and associated health disorders.

29 Mar 2023

High-resolution mass spectrometric rapid identification of Candida auris

A recent study published in the Journal of Fungi used a novel OrbitrapTM high-resolution mass spectrometric technology coupled with liquid chromatography to identify geographically different clades of Candida auris (C. auris) isolates. This proof-of-concept methodology could accurately detect C. auris in the microbiology laboratory.

23 Mar 2023

Zoonotic agent Erysipelothrix rhusiopathiae caused mass mortality of harbor porpoises

In a recent article published in the Emerging Infectious Diseases Journal, researchers in the Netherlands described a mortality event that killed hundreds of harbor porpoises (Phocoena phocoena), a small cetacean, along the Netherlands coastline, in August 2021.

22 Mar 2023

Study identifies link between oral and gut microbiomes and depression

Researchers investigate the role of the oral-gut-brain axis in anxiety and depression.

14 Mar 2023

EVOSEP and ReSyn Biosciences partner to integrate their technologies into new clinical proteomics solutions

The ability to process large and clinically relevant cohorts in a robust and high-throughput manner is important to unlocking the full potential of proteomics for precision medicine.

From Evosep 14 Mar 2023

Bispecific antibody shows improved efficacy against SARS-CoV-2 variants

Researchers from The University of Texas MD Anderson Cancer Center have developed fully human bispecific antibodies, as revealed in a recent study. These antibodies can bind to two distinct epitopes of the receptor binding domain (RBD) of the SARS-CoV-2 spike protein and have demonstrated the ability to neutralize various strains of the virus, including the Omicron variant.

14 Mar 2023

Hyperinflammation triggers long COVID headaches

Researchers characterize the immunological and metabolic alterations involved in chronic headache onset during post-acute sequelae of COVID-19.

13 Mar 2023

Mercury and urinary arsenobetaine in blood are strong biomarkers for seafood consumption among pregnant women

Mercury content in RBCs and arsenobetaine in urine could be considered seafood consumption biomarkers during pregnancy.

10 Mar 2023

Mass spectrometry-based identification of COVID-19 biomarkers

In a recent study published in the journal Metabolites, researchers reported that mass spectrometry (MS)-based metabolomic approaches have a high potential for biomarker discovery.

28 Feb 2023

Metabolomic differences in breast milk throughout lactation

Researchers characterize the cellular metabolome of breast milk throughout the course of lactation.

28 Feb 2023

Can the gut microbiota and metabolome explain variation in anti-SARS-CoV-2 vaccination responses in immunosuppressed IBD patients?

Researchers explored the connection between the metabolic function of the gut microbiota, its composition, and immune response to SARS-CoV-2 vaccination in IBD patients.

27 Feb 2023

New method to measure drugs and lipids in cells could lead to effective treatments for diseases

A new state-of-the-art method that measures the amounts of drugs and lipids (fats) in individual cells could help health professionals target more effective treatments for diseases such as tuberculosis (TB).

17 Feb 2023

Innovative method reveals new antioxidants in beef, chicken, and pork

Imidazole dipeptides (IDPs), which are abundant in meat and fish, are substances produced in the bodies of various animals, including humans, and have been reported to be effective in relieving fatigue and preventing dementia.

17 Feb 2023

How does previous diet impact the endocannabinoidome and microbiome response to a short-term Mediterranean diet intervention?

Researchers assessed the different impacts of diet on the gut microbiome.

15 Feb 2023

New analytical platform quantifies the structure of mRNA-based medicines

Researchers from Tokyo Metropolitan University and RIKEN CSRS have developed a new analytical platform based on liquid chromatography, mass spectrometry and software analysis that quantifies the structure of messenger RNA (mRNA) based medicines.

13 Feb 2023

New method for capturing moments during protein translation

Nascent polypeptide chains or polypeptidyl-tRNAs (pep-tRNAs) occur transiently during protein synthesis. The potential to study these intermediates and better understand their role in processes like gene regulation has been greatly enhanced by the development of a process termed PETEOS—short for peptidyl-tRNA enrichment using organic extraction and silica adsorption.

10 Feb 2023

Liquid Chromatography News and Research

Targeting obesity: findings reveal a new molecular pathway involved in energy homeostasis regulation

High-resolution mass spectrometric rapid identification of Candida auris

Zoonotic agent Erysipelothrix rhusiopathiae caused mass mortality of harbor porpoises

Study identifies link between oral and gut microbiomes and depression

EVOSEP and ReSyn Biosciences partner to integrate their technologies into new clinical proteomics solutions

Bispecific antibody shows improved efficacy against SARS-CoV-2 variants

Hyperinflammation triggers long COVID headaches

Mercury and urinary arsenobetaine in blood are strong biomarkers for seafood consumption among pregnant women

Mass spectrometry-based identification of COVID-19 biomarkers

Metabolomic differences in breast milk throughout lactation

Can the gut microbiota and metabolome explain variation in anti-SARS-CoV-2 vaccination responses in immunosuppressed IBD patients?

New method to measure drugs and lipids in cells could lead to effective treatments for diseases

Innovative method reveals new antioxidants in beef, chicken, and pork

How does previous diet impact the endocannabinoidome and microbiome response to a short-term Mediterranean diet intervention?

New analytical platform quantifies the structure of mRNA-based medicines

New method for capturing moments during protein translation

Diet, microbial metabolites, and cytokine levels correlate with depression and anxiety symptoms in obese individuals

Overweight people have a different vitamin D metabolism

Researchers identify plasma metabolomic markers for the Mediterranean diet among pregnant women

What impact does short-term sleep restriction have on gut microbiome?

Sensing a Healthier Future

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

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