Muscle Wasting News and Research

RSS

Terminally ill scientist replumbed as a Cyborg

A 61 year old British scientist suffering from a life threatening muscle wasting disease – motor neurone disease or MND, has managed to convert himself fully into a cyborg called Peter 2.0 making him the first to do so.

14 Nov 2019

UK’s first AI coaching tool to help people with chronic conditions

In an unprecedented partnership, a digital social enterprise and four UK health charities are coming together to harness the power of artificial intelligence for good– creating the UK’s first AI coaching tool of its kind to support long term health conditions.

25 Oct 2019

MDI Biological Laboratory scientist awarded federal grant for aging research

The MDI Biological Laboratory has announced that the U.S. Department of Health and Human Services has awarded a grant in the amount of $373,500 per year for five years to Aric Rogers, Ph.D., to support his research on the cellular and molecular mechanisms governing aging.

10 Oct 2019

New drug Aliskiren shows promise for heart failure patients

A study published in the International Journal of Molecular Sciences, as part of a special issue “Heart Failure: From Molecular Basis to Therapy”, in August 2019, shows that aliskiren, a drug approved by the US Food and Drug Administration (FDA), can improve survival for over 5 years, on average, and enhance life quality in patients who have been correctly diagnosed with heart failure.

9 Oct 2019

Aliskiren drug can delay progression of congestive heart failure, lengthen survival rates

Researchers at the University of Arizona College of Medicine - Phoenix have shown for the first time in preclinical studies that Aliskiren, a drug that inhibits the enzyme that regulates blood pressure, can delay the progression of congestive heart failure and lengthen survival rates.

8 Oct 2019

Researchers discover how cancer cells can trigger chronic muscle wasting condition

A solid tumor can cause muscle cells in the body to self-destruct. Many cancer patients die from the consequences. Now researchers are discovering more about how cancer cells in a tumor can take control of muscle cell wasting and trigger a chronic, serious condition.

19 Sep 2019

Prolonged opioid use linked to low testosterone

A new study has confirmed that a major effect of opioid overuse in adults is hypogonadism, or the abnormally low secretion of testosterone. This is associated with low sexual interest, loss of muscle and bone mass, increase in fatty tissue and infertility.

9 Sep 2019

Study examines screening and treatment of opioid-induced low testosterone in men

Long-term opioid use previously has been linked with low testosterone in men. What has been unclear is how many men taking opioids had been screened or treated for low testosterone.

8 Sep 2019

New improved model for cancer wasting syndrome cachexia

A new model of cancer-related cachexia promises to help scientists understand why patients with cancer show severe wasting, which in turn may drive the development of better therapies.

7 Aug 2019

New mouse model could lead to a better understanding of cachexia syndrome

A study published in Cell Reports Aug. 6 describes the generation of a new mouse model developed at Hollings Cancer Center that could lead to a better understanding of the cachexia syndrome. This wasting condition, characterized by excessive weight loss, has one of the highest incidences in pancreatic cancer patients.

6 Aug 2019

New book explains about the molecular mechanisms implicated in skeletal muscle aging

Sarcopenia, the progressive loss of muscle mass and associated muscle weakness during aging, affects the functional capacity and general health in adult people radically and renders frail elders susceptible to serious injury from sudden falls and fractures.

21 Jul 2019

Indigestion remedy improves survival in people with late-stage CKD

Defined as serum bicarbonate less than 22 mmol/L, metabolic acidosis is common in people with CKD stages 4-5 (eGFR < 30 ml/min/1.73 m2) and is directly related to worsening kidney function.

17 Jun 2019

Study uncovers trigger for cachexia

Among all major cancers, pancreatic cancer has the highest rate of death - 93 percent of patients die within five years of diagnosis.

13 Jun 2019

Scientists uncover unique set of genes that play a role in muscle cellular gene regulation

York University scientists have uncovered a unique set of genes that play a role in muscle cellular gene expression and differentiation which could lead to new therapeutic targets to prevent the spread of muscle cancer.

23 May 2019

Regular endurance exercise leads to high Nrf2 nuclear translocation, DNA binding activity

Skeletal muscle mass and function becomes progressively compromised with aging, chronic disease, and physical inactivity.

26 Apr 2019

Potential drug targets cause of adult-onset muscular dystrophy

People diagnosed with myotonic dystrophy type 1 have difficulty unclenching muscles due to a genetic defect that generates toxic material within their cells.

1 Apr 2019

Increased muscle mass could save your life

As far back as Ancient Greece, a sculptured physique has been heralded as the pinnacle of physical perfection. But now, researchers from Japan have found that increased muscle mass doesn't just make you look good, it could literally save your life.

4 Mar 2019

UCL and AIIMS collaborates to increase academic and student exchange

UCL and the All India Institute of Medical Sciences have entered into a new partnership which will enable much closer research collaboration and will explore opportunities to increase academic and student exchange between the institutions.

22 Feb 2019

Intense exercise, fasting and hormones can enhance waste-protein removal, study shows

The body's ability to adapt to changing conditions and shifting physiologic demands is essential to survival. To do so, each cell must be able to dispose of damaged or unnecessary proteins--a quality-control mechanism critical for cellular performance and for the health of the entire organism.

21 Feb 2019

Loss of muscle and body weight linked with disability in stroke patients

Loss of muscle and body weight is associated with disability after stroke, reports a study presented today at Heart & Stroke 2019, a meeting of the European Society of Cardiology Council on Stroke, and published in the Journal of Cachexia, Sarcopenia and Muscle.

25 Jan 2019